{"id":101726,"date":"2017-09-18T06:30:27","date_gmt":"2017-09-17T22:30:27","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=101726"},"modified":"2017-09-18T11:46:04","modified_gmt":"2017-09-18T03:46:04","slug":"%e5%a4%8f%e5%b9%bc%e5%8d%97adv-mater-%e4%b8%80%e5%a4%ab%e5%bd%93%e5%85%b3%ef%bc%8c%e4%b8%87%e5%a4%ab%e8%8e%ab%e5%bc%80%e8%bf%91%e7%ba%a2%e5%a4%96%e6%8e%a7%e5%88%b6%e7%9a%84","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=101726","title":{"rendered":"\u590f\u5e7c\u5357Adv. Mater.: \u201c\u4e00\u592b\u5f53\u5173\uff0c\u4e07\u592b\u83ab\u5f00\u201d\u8fd1\u7ea2\u5916\u63a7\u5236\u7684\u5171\u6676\u5929\u7136\u8102\u80aa\u9178\u76f8\u53d8\u5f15\u53d1\u836f\u7269\u91ca\u653e"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u667a\u80fd\u91ca\u836f\u7cfb\u7edf\u8fd1\u5e74\u6765\u53d1\u5c55\u8fc5\u731b\u3002\u5b83\u80fd\u5feb\u901f\u54cd\u5e94\u5916\u90e8\u523a\u6fc0\uff0c\u5e76\u6309\u9700\u91ca\u653e\u8d1f\u8f7d\u836f\u7269\u3002\u5728\u4f17\u591a\u4f53\u7cfb\u4e2d\uff0c\u4ee5\u5149\u54cd\u5e94\u523a\u6fc0\u7684\u5e94\u7528\u6700\u4e3a\u5e7f\u6cdb\uff0c\u56e0\u4e3a\u5b83\u53ef\u4ee5\u8fdc\u7a0b\u53d1\u6325\u9ad8\u7a7a\u95f4\u548c\u65f6\u95f4\u5206\u8fa8\u7387\u80fd\u529b\uff0c\u800c\u5176\u4e2d\u8fd1\u7ea2\u5916\u5149\u5177\u6709\u8f83\u597d\u7684\u8f6f\u7ec4\u7ec7\u7a7f\u900f\u6027\uff0c\u7814\u7a76\u5de5\u4f5c\u8005\u4eec\u5df2\u7ecf\u5f00\u53d1\u4e86\u591a\u79cd\u8fd1\u7ea2\u5916\u54cd\u5e94\u4f53\u7cfb\u3002\u76ee\u524d\u62a5\u9053\u7684\u5927\u591a\u6570\u8fd1\u7ea2\u5916\u54cd\u5e94\u7684\u667a\u80fd\u8f7d\u836f\u7cfb\u7edf\u90fd\u662f\u57fa\u4e8e\u9ad8\u5206\u5b50\u6e29\u654f\u6027\u7684\u6784\u8c61\u53d8\u5316\uff0c\u7136\u800c\u8fd9\u4e9b\u4f53\u7cfb\u7a0b\u5e8f\u590d\u6742\uff0c\u964d\u89e3\u80fd\u529b\u4f4e\u4e14\u6bd2\u6027\u4e0d\u53ef\u5ffd\u7565\uff0c\u56e0\u6b64\u65e0\u6cd5\u6ee1\u8db3\u4e34\u5e8a\u5e94\u7528\u7684\u8981\u6c42\u3002<\/p>\n

\u6709\u673a\u76f8\u53d8\u6750\u6599\u662f\u6700\u8fd1\u5174\u8d77\u7684\u4e00\u7c7b\u529f\u80fd\u6750\u6599\uff0c\u5b83\u4eec\u5177\u6709\u8f83\u9ad8\u7684\u7194\u5316\u6f5c\u70ed\uff0c\u5e76\u4e14\u80fd\u5728\u8f83\u7a84\u7684\u6e29\u5ea6\u8303\u56f4\u5185\u5b9e\u73b0\u56fa-\u6db2\u53ef\u9006\u53d8\u5316\uff0c\u4f46\u662f\u5728\u751f\u7406\u6761\u4ef6\u4e0b(37\u2103)\u7684\u53d8\u5316\u8fd8\u5e76\u672a\u88ab\u5b9e\u73b0\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u4f50\u6cbb\u4e9a\u7406\u5de5\u5b66\u9662\u590f\u5e7c\u5357\u6559\u6388\u56e2\u961f\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u8bbe\u8ba1\u5236\u5907\u4e86\u4e00\u79cd\u65b0\u578b\u7eb3\u7c73\u8f7d\u836f\u6750\u6599\uff0c\u8be5\u6750\u6599\u4ee5\u4e24\u79cd\u8102\u80aa\u9178\u5f62\u6210\u7684\u5171\u6676\u6df7\u5408\u7269\u80fd\u5feb\u901f\u54cd\u5e94\u8fd1\u7ea2\u5916\u5149\u7167\uff0c\u5b9e\u73b0\u836f\u7269\u63a7\u91ca\u3002\u8be5\u6750\u6599\u5177\u6709\u8f83\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u6e29\u63a7\u91cd\u590d\u6027\u3002\u540c\u65f6\u5728\u8d1f\u8f7dDOX\u548cIR780\u65f6\uff0c\u4f53\u5916\u5b9e\u9a8c\u548c\u7ec6\u80de\u5b9e\u9a8c\u90fd\u80fd\u5f88\u597d\u5730\u8fbe\u5230\u9884\u671f\u7684\u6548\u679c\u2014\u54cd\u5e94\u8fd1\u7ea2\u5916\u5149\u7167\u5feb\u901f\u91ca\u653e\u836f\u7269\uff0c\u8fbe\u5230\u5feb\u901f\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u7684\u76ee\u7684\u3002\u8be5\u7814\u7a76\u6210\u679c\u4ee5\u9898\u4e3a\u201cA Eutectic Mixture of Natural Fatty Acids Can Serve as the Gating Material for Near-Infrared-Triggered Drug Release<\/strong>\u201d\u53d1\u5e03\u5728\u56fd\u9645\u8457\u540d\u671f\u520aAdv. Mater.<\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe\u4e00\uff1a<\/strong>\u56fe\u6587\u6458\u8981<\/strong><\/p>\n

\"\"<\/p>\n

\u4e24\u79cd\u8102\u80aa\u9178\u5f62\u6210\u7684\u5171\u6676\u76f8\u53d8\u7eb3\u7c73\u7c92\u5b50\u54cd\u5e94\u8fd1\u7ea2\u5916\u5149\u7167\u5f15\u53d1\u836f\u7269\u5206\u5b50\u91ca\u653e\u3002<\/p>\n

\u56fe\u4e8c\uff1a<\/strong>\u76f8\u53d8\u6750\u6599\u4e0e\u5bf9\u5e94\u7eb3\u7c73\u7c92\u5b50\u7684\u8868\u5f81<\/strong><\/p>\n

\"\"<\/p>\n

(A) \u4e0d\u540c\u6bd4\u4f8b\u7684\u6708\u6842\u9178\u548c\u786c\u8102\u9178\u7684DSC\u66f2\u7ebf\uff1b<\/p>\n

(B) \u76f8\u53d8\u6750\u6599\u7eb3\u7c73\u7c92\u5b50\u7684TEM\u56fe\u50cf\uff1b<\/p>\n

(C) \u901a\u8fc7DLS\u89c2\u6d4b\u7684\u7eb3\u7c73\u7c92\u5b50\u7684\u7c92\u5f84\u5206\u5e03\uff1b<\/p>\n

(D) \u4e0d\u540c\u7269\u8d28\u7684\u7d2b\u5916-\u53ef\u89c1\u5149\u5438\u6536\uff08DOX-\u7ea2\u8272\uff0cIR780-\u84dd\u8272\uff0cDOX\/IR780\u7eb3\u7c73\u7c92\u5b50-\u7ea2\u8272\uff09\u3002<\/p>\n

\u56fe\u4e09\uff1a<\/strong>DOX\/IR780<\/strong>\u7eb3\u7c73\u7c92\u5b50\u7684\u5149\u70ed\u6548\u5e94<\/strong><\/p>\n

\"\"<\/p>\n

(A) 808 nm\u8fd1\u7ea2\u5916\u6fc0\u5149\uff080.4W cm-2<\/sup>\uff09\u7167\u5c04\u4e0b\u6c34\u3001\u9971\u548cIR780\u6eb6\u6db2\u548cDOX\/IR780\u7eb3\u7c73\u7c92\u5b50\u60ac\u6d6e\u6db2\u7684\u6e29\u5ea6\u53d8\u5316\uff1b<\/p>\n

(B) \u6c34\u3001\u9971\u548cIR780\u6eb6\u6db2\u548cDOX\/IR780\u7eb3\u7c73\u7c92\u5b50\u60ac\u6d6e\u6db2\u5728\u4e0d\u540c\u91cd\u590d\u6b21\u6570\u7684\u5149\u70ed\u6548\u5e94\u5bf9\u6bd4\uff1b<\/p>\n

(C) \u6fc0\u5149\u7167\u5c04\u4e0b\u6e38\u79bbIR780\u548cDOX\/IR780 NPs\u6fc0\u6d3b\u7684DCFH\u7684\u8367\u5149\u589e\u5f3a\u6bd4\uff080.4W cm-2<\/sup>\uff09\uff1b<\/p>\n

(D) \u6fc0\u5149\u7167\u5c04\u524d\u540eDOX\/IR780 \u7eb3\u7c73\u7c92\u5b50\u7d2f\u79efDOX\u91ca\u653e\u91cf\u3002<\/p>\n

\u56fe\u56db\uff1a<\/strong>DOX\/IR780 NPs<\/strong>\u7684\u7ec6\u80de\u6444\u53d6\u548c<\/strong>NIR<\/strong>\u5f15\u53d1\u7684\u836f\u7269\u91ca\u653e\u7684\u8bc1\u660e<\/strong><\/p>\n

\"\"<\/p>\n

\u8367\u5149\u56fe\u50cf\u663e\u793a\u5b75\u80b23\u5c0f\u65f6\u540eA549\u7ec6\u80de\u4e2dDOX\/IR780 NPs\u7684\u4f4d\u7f6e\uff1aHoechst 33342\uff08\u84dd\u8272\uff09\uff08A\uff09\uff0cLysotracker\uff08\u7eff\u8272\uff09\uff08B\uff09\uff0cDOX\uff08\u7ea2\u8272\uff09\uff08C\uff09\u548c\u5408\u5e76\u56fe\u50cf\uff08D\uff09\u3002E-G\uff1a\u4e0d\u540c\u65f6\u95f4\u7684DOX\u91ca\u653e\u5bf9\u6bd4\u3002\u523b\u5ea6\uff1a10\u03bcm\u3002<\/p>\n

\u56fe\u4e94\uff1a\u7ec6\u80de\u6bd2\u6027<\/strong><\/p>\n

\"\"<\/p>\n

\u5728\u4e0d\u540c\u7684DOX\/IR780\u7eb3\u7c73\u7c92\u5b50\u6d53\u5ea6\u4e0b\u7528\u4e0d\u540c\u7684\u6fc0\u5149\u7167\u5c04\u5b75\u80b28min\u7684A549\u7ec6\u80de\u7684\u7ec6\u80de\u5b58\u6d3b\u80fd\u529b\uff080.2W cm-2<\/sup>\uff09\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u672c\u6587\u4f5c\u8005\u8bbe\u8ba1\u5408\u6210\u4e86\u4e00\u79cd\u53ef\u8fd1\u7ea2\u5916\u89e6\u53d1\u836f\u7269\u91ca\u653e\u7684\u8102\u80aa\u9178\u76f8\u53d8\u7eb3\u7c73\u6750\u6599\u3002\u4e3a\u4e86\u786e\u4fdd\u5176\u8f83\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\uff0c\u5728\u5916\u7aef\u4fee\u9970\u4e86FDA\u6279\u51c6\u7684\u751f\u7269\u76f8\u5bb9\u6027\u805a\u5408\u7269\u3002\u540e\u671f\u5c06DOX\u548cIR780\u52a0\u5165\u5230\u76f8\u53d8\u6750\u6599\uff08PCM\uff09\u57fa\u8d28\u4e2d\u65f6\uff0c\u6750\u6599\u5177\u6709\u5f88\u597d\u7684\u5149\u70ed\u6548\u5e94\u548c\u5feb\u901f\u54cd\u5e94\u91ca\u653e\u80fd\u529b\uff0c\u7ec6\u80de\u5b9e\u9a8c\u8bc1\u660e\u5176\u5177\u6709\u8f83\u597d\u7684\u54cd\u5e94\u6027\u6297\u80bf\u7624\u80fd\u529b\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>A Eutectic Mixture of Natural Fatty Acids Can Serve as the\u00a0<\/a>Gating Material for Near-Infrared-Triggered Drug Release<\/a> (Adv. Mater., 2017, DOI: 10.1002\/adma.201703702)<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u674e\u5175\u7f16\u8bd1\uff0c\u8d75\u98de\u9f99\u5ba1\u6838\uff0c\u70b9\u6211\u52a0\u5165\u6750\u6599\u4eba\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n

\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c<\/strong>\u4e0a<\/strong>\u6d4b\u8bd5\u8c37<\/strong><\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u667a\u80fd\u91ca\u836f\u7cfb\u7edf\u8fd1\u5e74\u6765\u53d1\u5c55\u8fc5\u731b\u3002\u5b83\u80fd\u5feb\u901f\u54cd\u5e94\u5916\u90e8\u523a\u6fc0\uff0c\u5e76\u6309\u9700\u91ca\u653e\u8d1f\u8f7d\u836f\u7269\u3002\u5728\u4f17\u591a\u4f53\u7cfb\u4e2d\uff0c\u4ee5\u5149\u54cd\u5e94\u523a\u6fc0\u7684\u5e94\u7528\u6700\u4e3a\u5e7f\u6cdb\uff0c\u56e0\u4e3a\u5b83\u53ef\u4ee5\u8fdc\u7a0b\u53d1\u6325\u9ad8\u7a7a\u95f4\u548c\u65f6\u95f4\u5206\u8fa8\u7387\u80fd…<\/p>\n","protected":false},"author":230,"featured_media":101727,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215,2],"tags":[],"class_list":["post-101726","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","category-keji"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/101726"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/230"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=101726"}],"version-history":[{"count":2,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/101726\/revisions"}],"predecessor-version":[{"id":102537,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/101726\/revisions\/102537"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/media\/101727"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=101726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=101726"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=101726"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}