{"id":102402,"date":"2017-09-19T14:00:18","date_gmt":"2017-09-19T06:00:18","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=102402"},"modified":"2017-09-18T21:07:14","modified_gmt":"2017-09-18T13:07:14","slug":"%e8%8b%8f%e5%b7%9e%e5%a4%a7%e5%ad%a6%e5%88%98%e5%ba%84angew-chem-int-ed-%ef%bc%9a%e5%8f%af%e7%94%9f%e7%89%a9%e9%99%8d%e8%a7%a3%e7%9a%84%e5%a4%9a%e5%8a%9f%e8%83%bd%e6%97%a0%e6%9c%ba%e7%ba%b3","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=102402","title":{"rendered":"\u82cf\u5dde\u5927\u5b66\u5218\u5e84Angew. Chem. Int. Ed.\uff1a\u53ef\u751f\u7269\u964d\u89e3\u7684\u591a\u529f\u80fd\u65e0\u673a\u7eb3\u7c73\u80bf\u7624\u8bca\u7597\u8bd5\u5242"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u5149\u70ed\u7597\u6cd5\uff08PTT\uff09\uff0c\u4f5c\u4e3a\u4e00\u79cd\u975e\u4f20\u7edf\u7684\u80bf\u7624\u6cbb\u7597\u624b\u6bb5\uff0c\u4f9d\u8d56\u5728\u8fd1\u7ea2\u5916\u5904\u5f3a\u5438\u6536\u7684\u8bd5\u5242\u5c06\u5149\u80fd\u8f6c\u53d8\u4e3a\u70ed\u80fd\uff0c\u4ece\u800c\u5b9e\u73b0\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u7684\u76ee\u7684\u3002\u622a\u6b62\u76ee\u524d\uff0c\u5df2\u7ecf\u7814\u7a76\u51fa\u4e86\u8bb8\u591a\u6b64\u7c7b\u8bd5\u5242\u5e94\u7528\u5230\u4e86\u5149\u70ed\u6cbb\u7597\u4e2d\u3002\u53e6\u5916\uff0c\u7814\u7a76\u8005\u4eec\u8fd8\u53d1\u73b0\u5c06\u6210\u50cf\u6280\u672f\u540c\u5149\u70ed\u6cbb\u7597\u76f8\u7ed3\u5408\u53ef\u4ee5\u5927\u5927\u63d0\u9ad8\u80bf\u7624\u6cbb\u7597\u7684\u9776\u5411\u6027\u548c\u7075\u654f\u6027\u3002\u7136\u800c\uff0c\u53ef\u5b9e\u73b0\u8fd9\u4e00\u529f\u80fd\u7684\u65e0\u673a\u7eb3\u7c73\u8bd5\u5242\u7684\u751f\u7269\u4e0d\u53ef\u964d\u89e3\u6027\u6781\u5927\u5730\u963b\u788d\u4e86\u4e34\u5e8a\u53d1\u5c55\u3002\u591a\u5e74\u6765\uff0c\u4eba\u4eec\u4e00\u76f4\u81f4\u529b\u4e8e\u7814\u7a76\u51fa\u4e00\u79cd\u591a\u529f\u80fd\u7684\u751f\u7269\u53ef\u964d\u89e3\u7684\u65e0\u673a\u7eb3\u7c73\u8bd5\u5242\uff0c\u5176\u4e2d\u6700\u5e38\u89c1\u7684\u83ab\u8fc7\u4e8e\u8d85\u5c0f\u7eb3\u7c73\u9897\u7c92\uff0c\u867d\u7136\u89e3\u51b3\u4e86\u65e0\u6cd5\u6392\u51fa\u7684\u95ee\u9898\uff0c\u4f46\u591a\u6570\u65f6\u5019\u8fd9\u662f\u4ee5\u529f\u80fd\u5927\u5e45\u524a\u5f31\u4e3a\u4ee3\u4ef7\u7684\u3002\u56e0\u6b64\uff0c\u53d1\u5c55\u4e00\u79cd\u53ef\u751f\u7269\u964d\u89e3\u7684\u591a\u529f\u80fd\u65e0\u673a\u7eb3\u7c73\u8bd5\u5242\u5bf9\u4e8e\u80bf\u7624\u8bca\u7597\u7814\u7a76\u662f\u5f88\u6709\u610f\u4e49\u7684\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u6700\u8fd1\uff0c\u82cf\u5dde\u5927\u5b66\u5218\u5e84\u6559\u6388<\/strong>\u548c\u7a0b\u4eae\u526f\u6559\u6388\uff08\u5171\u540c\u901a\u8baf\uff09<\/strong>\u5728Angewandte Chemie International Edition<\/strong>\u4e0a\u53d1\u8868\u4e86\u9898\u4e3a\u201cDegradable Vanadium Disulfide Nanostructures with Unique Optical and Magnetic Functions for Cancer Theranostics\u201d<\/strong>\u7684\u7814\u7a76\u8bba\u6587\uff0c\u6587\u4e2d\u62a5\u9053\u4e86\u4e00\u79cd\u57fa\u4e8eVS2<\/sub>\u7684\u53ef\u964d\u89e3\u7eb3\u7c73\u8bd5\u5242\uff0c\u4ed6\u4eec\u5229\u7528PEG\u4fee\u9970\u7684\u8102\u8d28\u5c0f\u56ca\u5305\u88f9VS2<\/sub>\u7eb3\u7c73\u70b9\u5236\u5907\u4e86\u4e00\u79cd\u517c\u5177\u5149\u70ed\u8f6c\u6362\u548c\u591a\u6a21\u6210\u50cf\u529f\u80fd\u7684\u7eb3\u7c73\u8bd5VS2<\/sub>@lipid-PEG\uff0c\u6700\u91cd\u8981\u7684\u662f\u8be5\u8bd5\u5242\u5177\u6709\u751f\u7269\u53ef\u964d\u89e3\u6027\u4e14\u65e0\u660e\u663e\u6bd2\u526f\u4f5c\u7528\u3002\u6587\u4e2d\u4f5c\u8005\u5229\u7528VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u7c92\u5b50\uff0c\u8bc1\u5b9e\u4e86\u57fa\u4e8eVS2<\/sub>\u7684\u4f53\u5185\u78c1\u5171\u632f\u6210\u50cf\u3001\u5149\u58f0\u6210\u50cf\u548c\u5355\u7535\u5b50\u53d1\u5c04\u8ba1\u7b97\u673a\u65ad\u5c42\u626b\u63cf\u6210\u50cf\uff0c\u5e76\u5b9e\u73b0\u4e86VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u7c92\u5b50\u5e94\u7528\u4e8e\u591a\u6a21\u6210\u50cf\u6307\u5bfc\u7684\u5149\u70ed\u6cbb\u7597\u4e2d\uff0c\u4e14\u6548\u679c\u663e\u8457\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe1\uff1aVS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684\u5408\u6210\u4e0e\u8868\u5f81<\/strong>
\n \"\"
\n \uff08a\uff09VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684\u6784\u5efa\u8fc7\u7a0b\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09VS2<\/sub>\u7eb3\u7c73\u7247\u7684TEM\u56fe\u7247\uff1b
\n \uff08c\uff09VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684TEM\u56fe\u7247\uff1b
\n \uff08d\uff09VS2<\/sub>\u7eb3\u7c73\u7247\u548cVS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684\u7d2b\u5916\u53ef\u89c1\u8fd1\u7ea2\u5916\u5438\u6536\u5149\u8c31\uff1b
\n \uff08e\uff09\u4e0d\u540c\u6d53\u5ea6VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u5728\u6fc0\u5149\uff08808 nm\uff0c0.6 W\/cm2<\/sup>\uff09\u7167\u5c04\u4e0b\u7684\u5347\u6e29\u66f2\u7ebf\uff1b
\n \uff08f\uff09VS2<\/sub>@lipid-PEG (200 mgmL-1<\/sup>)\u7eb3\u7c73\u9897\u7c92\u6fc0\u5149\u7167\u5c045 min\u540e\u5173\u95ed\u7684\u5149\u70ed\u8f6c\u6362\u6548\u7387\uff1b
\n \uff08g\uff09\u6fc0\u5149\u7167\u5c04\u4e0b\uff0cVS2<\/sub>@lipid-PEG (200 mgmL-1<\/sup>)\u7eb3\u7c73\u9897\u7c92\u7684\u5149\u70ed\u7a33\u5b9a\u6027\u3002<\/p>\n

\u56fe2\uff1a\u4f53\u5185\u591a\u6a21\u6210\u50cf\u53ca\u5149\u70ed\u6cbb\u7597<\/strong>
\n \"\"
\n \uff08a\uff09\u78c1\u5171\u632fT1<\/sub>\u52a0\u6743\u50cf\u548cr1\u5f1b\u8c6b\u901f\u7387\u968fVS2<\/sub>@lipid-PEG\u6eb6\u6db2\u4e2dV\u6469\u5c14\u6d53\u5ea6\u7684\u53d8\u5316\u66f2\u7ebf\uff1a
\n \uff08b\uff09\u6ce8\u5c04VS2<\/sub>@lipid-PEG\u76844T1\u80bf\u7624\u5c0f\u9f20\u5728\u4e0d\u540c\u65f6\u95f4\u70b9\u7684\u78c1\u5171\u632fT1\u52a0\u6743\u50cf\uff1b
\n \uff08c\uff09\u4e0d\u540c\u65f6\u95f4\u70b9\u80bf\u7624\u5904\u78c1\u5171\u632f\u4fe1\u53f7\u7684\u5b9a\u91cf\u6bd4\u8f83\uff1b
\n \uff08d\uff09\u80bf\u7624\u5c0f\u9f20\u5728\u6ce8\u5c04\u524d\u4ee5\u53ca\u6ce8\u5c04VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c926\u5c0f\u65f6\u548c24\u5c0f\u65f6\u540e\u7684\u5149\u58f0\u6210\u50cf\uff08PA\uff09\uff1b
\n \uff08e\uff09\u80bf\u7624\u4f4d\u70b9\u5149\u58f0\u4fe1\u53f7\u7684\u5b9a\u91cf\u6bd4\u8f83\uff1b
\n \uff08f\uff09\u6ce8\u5c0499m<\/sup>Tc-VS2<\/sub>@lipid-PEG (500 mCi)\u540e\u4e0d\u540c\u65f6\u95f4\u70b94T1\u80bf\u7624\u5c0f\u9f20\u7684SPECT\u6210\u50cf\uff1b
\n \uff08g\uff09\u6ce8\u5c0424\u5c0f\u65f6\u540eVS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u5728\u4f53\u5185\u7684\u751f\u7269\u5206\u5e03\uff1b
\n \uff08h\uff09\u6ce8\u5c04VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c9224\u5c0f\u65f6\u8fdb\u884c\u6fc0\u5149\u7167\u5c04\u7684\u7ea2\u5916\u70ed\u81f4\u6210\u50cf\u56fe\uff1b
\n \uff08i\uff09\u6ce8\u5c04VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c9224\u5c0f\u65f6\u8fdb\u884c\u6fc0\u5149\u7167\u5c04\u7684\u80bf\u7624\u6e29\u5ea6\u968f\u65f6\u95f4\u53d8\u5316\u66f2\u7ebf\uff1b
\n \uff08j\uff09\u4e0d\u540c\u5b9e\u9a8c\u7ec4\u5c0f\u9f20\u5728\u7ecf\u8fc7\u4e0d\u540c\u7684\u6cbb\u7597\u540e\u80bf\u7624\u4f53\u79ef\u7684\u53d8\u5316\u66f2\u7ebf\u3002<\/p>\n

\u56fe3\uff1a VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684\u4f53\u5185\u6e05\u9664\u884c\u4e3a\u4e0e\u673a\u7406<\/strong>
\n \"\"
\n \uff08a\uff091\uff0c7\uff0c14\uff0c30\u5929\u540eVS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u5728\u5c0f\u9f20\u4f53\u5185\u7684\u751f\u7269\u5206\u5e03\uff1b
\n \uff08b\uff09\u6ce8\u5c041\uff0c7\uff0c14\uff0c30\u5929\u540e\u7caa\u4fbf\u53ca\u5c3f\u6db2\u4e2d\u6d4b\u5f97\u7684V\u7684\u8d28\u91cf\uff1b
\n \uff08c\uff09VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u5728\u7a7a\u6c14\u4e2d\u66b4\u97321\uff0c7\uff0c14\uff0c30\u5929\u540e\u7684\u7d2b\u5916\u53ef\u89c1\u8fd1\u7ea2\u5916\u5438\u6536\u5149\u8c31\uff1b
\n \uff08d\uff09VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u5728\u7a7a\u6c14\u4e2d\u66b4\u97321\uff0c7\uff0c14\uff0c30\u5929\u540e\u7684\u6570\u7801\u7167\u7247\uff1b
\n \uff08e\uff09VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c9230\u5929\u964d\u89e3\u524d\u540e\u7684TEM\u56fe\u7247\uff1b
\n \uff08f\uff09\u65b0\u5236VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684XPS\u8c31\u56fe\uff1b
\n \uff08g\uff09\u964d\u89e314\u5929\u540eVS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u7684XPS\u8c31\u56fe\uff1b
\n \uff08h\uff09VS2<\/sub>@lipid-PEG\u7eb3\u7c73\u9897\u7c92\u5728\u4f53\u5185\u6c27\u5316\u3001\u964d\u89e3\u3001\u6392\u51fa\u7684\u673a\u7406\u89e3\u91ca\u793a\u610f\u56fe\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u672c\u6587\u5236\u5907\u4e86\u4e00\u79cd\u57fa\u4e8eVS2<\/sub>\u7684\u53ef\u751f\u7269\u964d\u89e3\u7684\u65e0\u673a\u7eb3\u7c73\u8bd5\u5242\u5e76\u5c06\u5176\u5e94\u7528\u4e8e\u591a\u6a21\u6001\u6210\u50cf\u548c\u80bf\u7624\u5149\u70ed\u6cbb\u7597\u4e2d\uff0c\u8868\u73b0\u51fa\u5f88\u597d\u7684\u80bf\u7624\u6cbb\u7597\u6548\u679c\uff0c\u63a8\u52a8\u4e86\u80bf\u7624\u5149\u70ed\u6cbb\u7597\u7814\u7a76\u7684\u53d1\u5c55\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Degradable Vanadium Disulfide Nanostructures with Unique Optical and Magnetic Functions for Cancer Theranostics.<\/a> (Angew. Chem. Int. Ed., 2017, DOI: 10.1002\/anie.201707128)<\/p>\n

\u56e2\u961f\u4ecb\u7ecd\uff1a<\/strong><\/p>\n

\u5218\u5e84\u6559\u6388\u4e8e2004\u5e74\u5728\u5317\u4eac\u5927\u5b66\u83b7\u5b66\u58eb\u5b66\u4f4d\uff1b2008\u5e74\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\u83b7\u535a\u58eb\u5b66\u4f4d\uff1b2009\u5e746\u6708\u52a0\u5165\u82cf\u5dde\u5927\u5b66\u529f\u80fd\u7eb3\u7c73\u4e0e\u8f6f\u7269\u8d28\u7814\u7a76\u9662\u3002\u8fd1\u5e74\u6765\u5728\u7eb3\u7c73\u751f\u7269\u533b\u5b66\u6750\u6599\u4e0e\u80bf\u7624\u7eb3\u7c73\u6280\u672f\u9886\u57df\u4ece\u4e8b\u7814\u7a76\uff0c\u5171\u53d1\u8868\u5b66\u672f\u8bba\u6587200\u4f59\u7bc7\uff0c\u8bba\u6587\u603b\u5f15\u7528\u8d85\u8fc729,000\u6b21\uff0cSCI H-index = 82\u30022012\u5e74\u83b7\u57fa\u91d1\u59d4\u4f18\u79c0\u9752\u5e74\u57fa\u91d1\u8d44\u52a9\uff1b2013\u5e74\u5165\u9009\u767e\u5343\u4e07\u4eba\u624d\u5de5\u7a0b\u56fd\u5bb6\u7ea7\u4eba\u9009\uff1b 2015\u5e74\u83b7\u56fd\u5bb6\u6770\u51fa\u9752\u5e74\u57fa\u91d1\u8d44\u52a9\uff1b2015\u5e74\u5165\u9009\u4e2d\u7ec4\u90e8\u4e07\u4eba\u8ba1\u5212\u201c\u9752\u5e74\u62d4\u5c16\u4eba\u624d\u201d\uff1b2016\u5e74\u5165\u9009\u79d1\u6280\u90e8\u201c\u4e2d\u9752\u5e74\u79d1\u6280\u521b\u65b0\u9886\u519b\u4eba\u624d\u201d\uff1b2016\u5e74\u83b7\u6c5f\u82cf\u7701\u79d1\u5b66\u6280\u672f\u4e00\u7b49\u5956\uff08\u7b2c\u4e00\u5b8c\u6210\u4eba\uff09\uff1b2017\u5e74\u83b7Biomaterials Science Lectureship\u30022015\u5e74\u53d7\u9080\u6210\u4e3a\u82f1\u56fd\u7687\u5bb6\u5316\u5b66\u4f1aFellow\uff1b2015\u30012016\u5e74\u8fde\u7eed\u5165\u9009Thomson Reuters\u53d1\u5e03\u7684\u201c\u5168\u7403\u9ad8\u5f15\u7528\u79d1\u5b66\u5bb6\u540d\u5f55\u201d\uff08Highly Cited Researchers\uff09\uff08\u5316\u5b66\u3001\u6750\u6599\uff09\uff1b\u62c5\u4efb\u751f\u7269\u6750\u6599\u9886\u57df\u56fd\u9645\u8457\u540d\u671f\u520aBiomaterials\u6742\u5fd7\u526f\u4e3b\u7f16\u548c\u591a\u4e2a\u56fd\u9645\u4e3b\u6d41\u671f\u520a\u7f16\u59d4\u3002<\/p>\n

\u7a0b\u4eae\u526f\u6559\u6388\u4e8e2012\u5e746\u6708\u5728\u82cf\u5dde\u5927\u5b66\u83b7\u535a\u58eb\u5b66\u4f4d\uff0c\u4e4b\u540e\u7559\u6821\u5de5\u4f5c\u3002\u8fd1\u5e74\u6765\u4e3b\u8981\u7814\u7a76\u65b9\u5411\u662f\u529f\u80fd\u7eb3\u7c73\u6750\u6599\u8bbe\u8ba1\u53ca\u5176\u5728\u751f\u7269\u6210\u50cf\u548c\u764c\u75c7\u6cbb\u7597\u7b49\u65b9\u9762\u7684\u5e94\u7528\u3002\u5728\u56fd\u9645\u5b66\u672f\u671f\u520a\u5171\u53d1\u8868\u5b66\u672f\u8bba\u6587\u5171100\u4f59\u7bc7\uff0c\u5176\u4e2d\u7b2c\u4e00\u6216\u901a\u8baf\u4f5c\u8005\u8bba\u658740\u4f59\u7bc7\uff0c\u90e8\u5206\u53d1\u8868\u5728Chem Rev, Angew Chem, Adv Mater, ACS Nano, Adv Funct Mater, Biomaterials\u7b49\u4e0a\u3002\u8bba\u6587\u603b\u5f15\u7528\u8d85\u8fc76000\u6b21\uff0cH-index\u56e0\u5b50\u4e3a44\uff0c\u5e76\u83b7\u5f97\u591a\u9879\u79d1\u7814\u9879\u76ee\u8d44\u52a9\u3002<\/p>\n

\u56e2\u961f\u8fd1\u671f\u4ee3\u8868\u6027\u5de5\u4f5c\uff1a<\/strong><\/p>\n

1. Chen, Q.; Xu, L.; Liang, C.; Wang, C.; Peng, R.; Liu, Z. Photothermal Therapy with Immune-adjuvant Nanoparticles together with Checkpoint Blockade for Effective Cancer Immunotherapy. Nature Communications 2016, 7, 13193.
\n 2. Chen, Q.; Liang, C.; Sun, X.; Chen, J.; Yang, Z.; Zhao, H.; Feng, L.; Liu, Z. H2O2-Responsive Liposomal Nanoprobe for Photoacoustic Inflammation Imaging and Tumor Theranostics via in vivo Chromogenic Assay. Proceedings of the National Academy of Sciences 2017, 114, 5343-5348.
\n 3. Song, G.; Cheng, L.; Chao, Y.; Yang, K.; Liu, Z. Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy. Advanced Materials, 2017, DOI:10.1002\/adma.201700996.
\n 4. Gao, M.; Liang, C.; Song, X.; Chen, Q.; Jin, Q.; Wang, C.; Liu, Z. Erythrocyte-Membrane-Enveloped Perfluorocarbon as Nanoscale Artificial Red Blood Cells to Relieve Tumor Hypoxia and Enhance Cancer Radiotherapy. Advanced Materials, 2017, DOI: 10.1002\/adma.201701429
\n 5. Yang, Y.; Zhu, W.; Dong, Z.; Chao, Y.; Xu, L.; Chen, M.; Liu, Z. 1D Coordination Polymer Nanofibers for Low-Temperature Photothermal Therapy. Advanced Materials, 2017. DOI: 10.1002\/adma.201703588
\n 6. Chen, Y.; Cheng, L.; Dong, Z.; Chao, Y.; Lei, H.; Zhao, H.; Wang, J.; Liu, Z. Degradable Vanadium Disulfide Nanostructures with Unique Optical and Magnetic Functions for Cancer Theranostics. Angewandte Chemie International Edition, 2017, DOI: 10.1002\/anie.201707128
\n 7. Shen, S.; Jiang, D.; Cheng, L.; Chao, Y.; Nie, K.; Dong, Z.; Kutyreff, C. J.; Engle, J. W.; Huang, P.; Cai, W.; Liu, Z. Renal-Clearable Ultrasmall Coordination Polymer Nanodots for Chelator-Free 64Cu-Labeling and Imaging-Guided Enhanced Radiotherapy of Cancer. ACS Nano 2017, DOI: 10.1021\/acsnano.7b03857
\n 8. Feng, L.; Cheng, L.; Dong, Z.; Tao, D.; Barnhart, T. E.; Cai, W.; Chen, M.; Liu, Z. Theranostic Liposomes with Hypoxia-Activated Prodrug to Effectively Destruct Hypoxic Tumors Post-Photodynamic Therapy. ACS Nano 2017, 11, 927-937.
\n 9. Xu, J.; Xu, L.; Wang, C.; Yang, R.; Zhuang, Q.; Han, X.; Dong, Z.; Zhu, W.; Peng, R.; Liu, Z. Near-Infrared-Triggered Photodynamic Therapy with Multitasking Upconversion Nanoparticles in Combination with Checkpoint Blockade for Immunotherapy of Colorectal Cancer. ACS Nano 2017, 11, 4463-4474.<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u751f\u7269\u6750\u6599\u7ec4Jing\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n

\u53c2\u4e0e\u751f\u7269\u6750\u6599\u8bdd\u9898\u8ba8\u8bba\u6216\u4e86\u89e3\u751f\u7269\u6750\u6599\u5c0f\u7ec4\u62db\u52df\u8be6\u60c5\uff0c\u8bf7\u52a0\u5165\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u4ea4\u6d41\u7fa4\uff08124806506\uff09\u3002<\/p>\n

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