{"id":110369,"date":"2017-11-09T06:30:38","date_gmt":"2017-11-08T22:30:38","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=110369"},"modified":"2017-11-09T12:02:16","modified_gmt":"2017-11-09T04:02:16","slug":"acs-nano%ef%bc%9a%e9%80%9a%e8%bf%87znopdargdc%e7%ba%b3%e7%b1%b3%e6%a3%92%e7%9a%84%e9%80%89%e6%8b%a9%e6%80%a7%e7%89%a9%e7%90%86%e7%a9%bf%e5%88%ba%e5%92%8c%e7%94%9f%e7%89%a9%e5%8a%9f%e8%83%bd%e5%8c%96","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=110369","title":{"rendered":"ACS Nano\uff1a\u901a\u8fc7ZnO\/PDA\/RGDC\u7eb3\u7c73\u68d2\u7684\u9009\u62e9\u6027\u7269\u7406\u7a7f\u523a\u548c\u751f\u7269\u529f\u80fd\u5316\u5e73\u8861\u7ec6\u83cc-\u6210\u9aa8\u7ec6\u80de\u7ade\u4e89"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u9aa8\u79d1\u624b\u672f\u540e\u6709\u91cf\u5927\u5e76\u53d1\u75c7\uff0c\u5373\u611f\u67d3\u548c\u4e0d\u5145\u5206\u7684\u9aa8\u6574\u5408\uff0c\u5e76\u56e0\u6b64\u5bfc\u81f4\u79cd\u690d\u4f53\u677e\u52a8\u3001\u9aa8\u6298\u7578\u5f62\u6108\u5408\u6216\u4e0d\u6108\u5408\u4ee5\u53ca\u690d\u5165\u5931\u8d25\u3002\u611f\u67d3\u901a\u5e38\u662f\u7531\u4e8e\u79cd\u690d\u4f53\u8868\u9762\u7ec6\u83cc\u7c98\u9644\u548c\u751f\u7269\u819c\u5f62\u6210\u3002\u7531\u4e8e\u80fd\u591f\u62b5\u6297\u5bbf\u4e3b\u9632\u5fa1\u548c\u6297\u751f\u7d20\uff0c\u4e00\u4e2a\u6210\u719f\u7684\u7ec6\u83cc\u751f\u7269\u819c\u53ef\u4ee5\u4f7f\u57fa\u4e8e\u7cfb\u7edf\u6027\u6297\u751f\u7d20\u7684\u4f20\u7edf\u6cbb\u7597\u65b9\u6cd5\u65e0\u6548\u3002\u5728\u4e25\u91cd\u7684\u60c5\u51b5\u4e0b\uff0c\u9700\u8981\u4e8c\u6b21\u624b\u672f\u79fb\u53bb\u690d\u5165\u7269\u3002\u8fd9\u4e0d\u4ec5\u589e\u52a0\u60a3\u8005\u521b\u4f24\u4e5f\u63d0\u9ad8\u4e86\u8d39\u7528\u3002\u56e0\u6b64\uff0c\u6709\u5fc5\u8981\u4f7f\u4eba\u5de5\u690d\u5165\u6750\u6599\u5177\u6709\u6709\u6548\u7684\u81ea\u6211\u6297\u83cc\u80fd\u529b\u3002\u76ee\u524d\u591a\u79cd\u65b9\u6cd5\u88ab\u5e94\u7528\u4e8e\u6b64\uff0c\u5305\u62ec\u6297\u83cc\u7ed3\u6784\u3001\u6297\u83cc\u80bd\u3001\u94f6\u7eb3\u7c73\u9897\u7c92\u7b49\u6280\u672f\u3002\u7136\u800c\uff0c\u5f53\u6297\u83cc\u5242\u52a0\u5165\u4ee5\u63d0\u9ad8\u6297\u83cc\u6027\u7684\u65f6\u5019\uff0c\u9aa8\u8bf1\u5bfc\u6027\u5f80\u5f80\u964d\u4f4e\u800c\u6bd2\u6027\u4e0a\u5347\u3002\u56e0\u6b64\uff0c\u5173\u952e\u662f\u5728\u6291\u5236\u7ec6\u83cc\u7684\u540c\u65f6\uff0c\u5141\u8bb8\u8db3\u591f\u7684\u6210\u9aa8\u7ec6\u80de\u751f\u957f\uff0c\u4e5f\u5c31\u662f\u5e73\u8861\u7ec6\u83cc\u548c\u6210\u9aa8\u7ec6\u80de\u4e4b\u95f4\u7684\u7ade\u4e89\u3002\u7ec6\u80de\u548c\u7ec6\u83cc\u7684\u7c98\u9644\u53ef\u4ee5\u901a\u8fc7\u4e0d\u540c\u7ed3\u6784\u7684\u8868\u9762\u5f62\u8c8c\u6765\u8c03\u8282\u3002\u7531\u4e8e\u6210\u9aa8\u7ec6\u80de\u7684\u5927\u5c0f\u6bd4\u7ec6\u83cc\u5927\u4e00\u4e2a\u6570\u91cf\u7ea7\uff0c\u6210\u9aa8\u7ec6\u80de\u548c\u7ec6\u83cc\u5bf9\u7eb3\u7c73\u68d2\u9635\u5217\u7684\u654f\u611f\u6027\u6709\u5f88\u5927\u7684\u5dee\u522b\u3002\u751f\u7269\u6750\u6599\u4e0e\u9002\u5f53\u7684\u950c\u7ed3\u5408\uff0c\u53ef\u4fc3\u8fdb\u4f53\u5916\u548c\u4f53\u5185\u7684\u521d\u59cb\u7ec6\u80de\u7c98\u9644\u3001\u94fa\u5c55\u3001\u589e\u6b96\u3001\u6210\u9aa8\u5206\u5316\u3001\u9aa8\u5f62\u6210\u548c\u77ff\u5316\u3002\u867d\u7136\u7eb3\u7c73\u6c27\u5316\u950c\u5177\u6709\u826f\u597d\u7684\u6297\u83cc\u6d3b\u6027\uff0c\u4f46\u7531\u4e8e\u5927\u91cf\u7684Zn2+\u5bf9\u7ec6\u80de\u751f\u957f\u548c\u7ec4\u7ec7\u5f62\u6210\u4ea7\u751f\u4e0d\u5229\u5f71\u54cd\uff0c\u6d3b\u6027\u6c27\uff08ROS\uff09\u53ef\u8bf1\u5bfc\u7ec6\u80de\u51cb\u4ea1\uff0c\u56e0\u6b64\u5177\u6709\u660e\u663e\u7684\u7ec6\u80de\u6bd2\u4f5c\u7528\u3002\u56e0\u6b64\uff0c\u63a7\u5236\u950c\u79bb\u5b50\u7684\u91ca\u653e\u548c\u7eb3\u7c73\u6c27\u5316\u950c\u7684\u751f\u6210\u662f\u5e73\u8861\u6297\u83cc\u6d3b\u6027\u548c\u7ec6\u80de\u6bd2\u6027\u7684\u5173\u952e\u3002\u805a\u591a\u5df4\u80fa\uff08PDA\uff09\u5177\u6709\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u3001\u751f\u7269\u964d\u89e3\u6027\u3001\u4eb2\u6c34\u6027\u3002\u6b64\u5916\uff0cPDA\u5177\u6709\u8f83\u5f3a\u7684\u6297\u6c27\u5316\u4f5c\u7528\uff0c\u53ef\u6e05\u9664\u53cd\u5e94\u6027\u81ea\u7531\u57fa\u3002PDA\u4e0e\u80fa\u548c\/\u6216\u542b\u786b\u9187\u5206\u5b50\u4e4b\u95f4\u7684\u53cd\u5e94\u6709\u5229\u4e8e\u751f\u7269\u6d3b\u6027\u5206\u5b50\u7684\u63a5\u679d\u3002\u7c7b\u4f3c\u7684\u7cbe\u6c28\u9178\u7518\u6c28\u9178-\u5929\u51ac\u6c28\u9178\uff08RGD\uff09\u3001RGD cysteine\uff08RGDC\uff09\u662f\u63d0\u9ad8\u8bb8\u591a\u7c7b\u578b\u7684\u7ec6\u80de\u9644\u7740\u5230\u4e0d\u540c\u7684\u57fa\u677f\uff0c\u53ef\u4ee5\u6709\u6548\u6fc0\u6d3b\u7ec6\u80de\u6574\u5408\u7d20\u7684\u7c98\u9644\u53d7\u4f53\uff0c\u56e0\u6b64\uff0c\u5bf9\u80bd\u5171\u4ef7\u7ed3\u5408\u662f\u4e00\u4e2a\u53ef\u884c\u7684\u7b56\u7565\u6765\u63d0\u9ad8\u7ec6\u80de\u7684\u7c98\u9644\u548c\u589e\u6b96\u7684\u6210\u9aa8\u6027\u80fd\u7684\u63d0\u9ad8\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u6e56\u5317\u5927\u5b66\u3001\u5929\u6d25\u5927\u5b66\u3001\u9999\u6e2f\u57ce\u5e02\u5927\u5b66\u4ee5\u53ca\u9999\u6e2f\u5927\u5b66\u7684\u79d1\u7814\u56e2\u961f<\/strong>\u5408\u4f5c\u8bbe\u8ba1\u4e86\u6c27\u5316\u950c\/\u805a\u591a\u5df4\u80fa\uff08PDA\uff09\/\u7cbe\u6c28\u9178\u7518\u6c28\u9178\u5929\u51ac\u6c28\u9178\u534a\u80f1\u6c28\u9178-\u534a\u80f1\u6c28\u9178\uff08RGDC\uff09\u7eb3\u7c73\u68d2\uff08NR\uff09\u9635\u5217\u5e76\u5c06\u5176\u7528\u4e8e\u949b\uff08Ti\uff09\u690d\u5165\u7269\uff0c\u4e0d\u4ec5\u63d0\u9ad8\u4e86\u9aa8\u8bf1\u5bfc\u6027\u540c\u65f6\u8fd8\u80fd\u6709\u6548\u6740\u6b7b\u7ec6\u83cc\u3002\u8fd9\u90fd\u5f52\u56e0\u4e8e\u5728\u7ec6\u83cc\u4e0e\u6210\u9aa8\u7ec6\u80de\u4e4b\u95f4\u7ade\u4e89\u4e2d\uff0cZnO\/ PDA \/RGDC\u7eb3\u7c73\u68d2\u7684\u9009\u62e9\u6027\u7269\u7406\u7a7f\u523a\u548c\u751f\u7269\u529f\u80fd\u5316\u3002\u7531\u4e8e\u6210\u9aa8\u7ec6\u80de\u7684\u5c3a\u5bf8\u6bd4\u7ec6\u83cc\u5927\u5f97\u591a\uff0c\u590d\u5408\u7eb3\u7c73\u68d2\u53ef\u4ee5\u7a7f\u523a\u7ec6\u83cc\u800c\u4e0d\u635f\u4f24\u6210\u9aa8\u7ec6\u80de\u3002\u540c\u65f6\uff0c\u901a\u8fc7\u6291\u5236\u6d3b\u6027\u6c27\u548c\u9ad8\u950c\u79bb\u5b50\u6d53\u5ea6\uff0c\u8986\u76d6\u7684PDA\u548cRGDC\u63d0\u9ad8\u4e86\u7ec6\u80de\u76f8\u5bb9\u6027\u3002\u4f53\u5916\u5b9e\u9a8c\u8bc1\u5b9e\u4e86\u7ec6\u83cc\u819c\u7684\u9009\u62e9\u6027\u7a7f\u523a\u548c\u66f4\u597d\u7684\u6210\u9aa8\u6d3b\u6027\u3002\u4f53\u5185\u8bd5\u9a8c\u4e5f\u901a\u8fc7\u5468\u56f4\u7ec4\u7ec7\u4e2d\u66f4\u5c11\u7684\u4e2d\u6027\u7c92\u7ec6\u80de\u5206\u53f6\u548c\u7ec6\u83cc\u7c98\u9644\u663e\u793a\u51fa\u66f4\u9ad8\u7684\u6297\u83cc\u6548\u679c\u3002\u6b64\u5916\uff0c\u5373\u4f7f\u5728\u6ce8\u5c04\u4e86\u7ec6\u83cc\u7684\u60c5\u51b5\u4e0b\uff0c\u590d\u5408\u7eb3\u7c73\u68d2\u4e5f\u52a0\u5feb\u4e86\u65b0\u9aa8\u7ec4\u7ec7\u5f62\u6210\uff08\u6bd4\u7eaf\u949b\u9ad820.1%\uff09\u4ee5\u53ca\u690d\u5165\u7269\u548c\u4e0e\u65b0\u5f62\u6210\u7ec4\u7ec7\u7684\u9aa8\u6574\u5408\uff08\u6bd4\u7eaf\u949b\u9ad832%\uff09\u3002\u76f8\u5173\u6210\u679c\u4ee5\u9898\u4e3a\u201cBalancing Bacteria\u2212Osteoblast Competition through Selective Physical Puncture and Biofunctionalization of ZnO\/Polydopamine\/ Arginine-Glycine-Aspartic Acid-Cysteine Nanorods \u201d<\/strong>\u53d1\u8868\u5728\u4e86ACS Nano<\/strong>\u4e0a\u3002\u8bba\u6587\u7684\u901a\u8baf\u4f5c\u8005<\/strong>\u4e3a\u5434\u6c34\u6797\u6559\u6388<\/strong>\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u793a\u610f\u56fe1 \u901a\u8fc7ZnO\/PDA\/RGDC\u6df7\u5408\u7eb3\u7c73\u68d2\u9635\u5217\u5e73\u8861\u79cd\u949b\u690d\u4f53\u8868\u9762\u7ec6\u83cc-\u6210\u9aa8\u7ec6\u80de\u7ade\u4e89\u7684\u793a\u610f\u56fe<\/strong><\/p>\n

\"\"<\/p>\n

\u56fe1 \u6750\u6599\u7684\u5236\u5907\u4e0e\u8868\u5f811<\/strong><\/p>\n

\"\"<\/p>\n

(A)\u5236\u5907\u949b\u8868\u9762\u6df7\u5408ZnO\/PDA\/RGDC\u7eb3\u7c73\u9635\u5217\u7684\u793a\u610f\u56fe\uff1b<\/p>\n

FE-SEM\u56fe(B) Ti- ZnOs (\u6bd4\u4f8b\u5c3a=100 nm)\uff0c(C) Ti-ZnO, (D)Ti-ZnO\/PDA, (E) Ti-ZnO\/PDA\/RGDC\uff1b<\/p>\n

(E1) Ti-ZnO\/PDA\/ RGDC \u6a2a\u65ad\u9762\uff1b<\/p>\n

(E2) Ti-ZnO\/PDA\/ RGDC\u5143\u7d20\u6620\u5c04 (\u6bd4\u4f8b\u5c3a=100 nm(\u63d2\u5165\u56fe=1 \u03bcm))<\/p>\n

\u56fe2 \u6750\u6599\u7684\u5236\u5907\u4e0e\u8868\u5f812<\/strong><\/p>\n

\"\"<\/p>\n

(A) Ti, Ti-ZnOs, Ti-ZnO, Ti-ZnO\/PDA\u548cTi-ZnO\/PDA\/RGDC\u7684XRD\u5206\u6790\uff1b<\/p>\n

(B) Ti-ZnO\/PDA \u548cTi- ZnO\/PDA\/RGDC\u7684\u5085\u91cc\u53f6\u5206\u6790\uff1b<\/p>\n

(C) Ti-ZnO, Ti-ZnO\/PDA, \u548cTi-ZnO\/PDA\/RGDC\u7684XPS\u5206\u6790\uff1b<\/p>\n

(C1) Ti-ZnO\/PDA\u5cf0 (C2) Ti-ZnO\/PDA\/RGDC\u5cf0;<\/p>\n

(D) Ti, Ti-ZnOs, Ti-ZnO, Ti-ZnO\/PDA, \u548cTi-ZnO\/PDA\/RGDC\u4e0a\u7684\u6c34\u63a5\u89e6\u89d2\u53ca\u793a\u610f\u56fe\u3002<\/p>\n

\u8bef\u5dee\u6761\u8868\u793a\u5747\u503c\u00b1 \u6807\u51c6\u5dee: *P < 0.05 and ***P < 0.001 (t\u68c0\u9a8c)<\/p>\n

\u56fe3 \u6750\u6599\u7684\u5236\u5907\u4e0e\u8868\u5f813<\/strong><\/p>\n

\"\"<\/p>\n

(A) Ti-ZnO, Ti-ZnO\/PDA,\u548cTi-ZnO\/PDA\/RGDC\u7684\u950c\u79bb\u5b50\u7d2f\u79ef\u91ca\u653e\u91cf\uff1b<\/p>\n

(A1) \u77ed\u671f\u91ca\u653e\uff1b<\/p>\n

(B)\u5bf9\u5e94A1\u7684\u6eb6\u6db2pH\u503c\uff1bPDA\u7684\u964d\u89e3<\/p>\n

(C)\u7d2b\u5916\u53ef\u89c1\u5438\u6536\u5149\uff1b<\/p>\n

(D) \u5bf9\u5e94\u7167\u7247, (E) \u5bf9PDA\u5316\u5b66\u964d\u89e3\u9014\u5f84\uff08R\u7ec4\u56feS5\uff09\u63d0\u51fa\u7684\u5316\u5b66\u516c\u5f0f\uff1b<\/p>\n

(F) Ti, Ti-ZnOs, Ti-ZnO, Ti-ZnO\/PDA\u548cTi-ZnO\/PDA\/RGDC\u7684ESR\u8c31\uff1b<\/p>\n

(G) PDA\u548cPDA\/ZnO\u76841H HMR\u8c31\uff1b<\/p>\n

(H) Zn-PDA\u590d\u5408\u7269\u7684\u7ed3\u6784\u3002<\/p>\n

\u56fe4 \u6750\u6599\u7684\u6297\u83cc\u6027\u6d4b\u8bd51<\/strong><\/p>\n

\"\"<\/p>\n

(A) \u591a\u79cd\u8868\u9762\u7ecf\u91d1\u8461\u83cc\u548c\u5927\u80a0\u6746\u83cc\u5904\u7406\u540e\u7684\u8367\u5149\u56fe\u50cf(\u6bd4\u4f8b\u5c3a = 50 \u03bcm)\uff1b<\/p>\n

(B) \u5927\u80a0\u6746\u83cc\u548c\u91d1\u8461\u83cc\u79cd\u4e8e\u591a\u79cd\u8868\u9762\u7684FE- SEM\u56fe(\u6bd4\u4f8b\u5c3a = 100 nm). \u4e0d\u540c\u6837\u672c\u6297\u83cc\u6027\uff1a\u5728\u743c\u8102\u677f\u4e0a\u518d\u57f9\u517b\u7684\u7ec6\u83cc\u514b\u9686\u83cc\u843d\uff1b<\/p>\n

(C) \u91d1\u8461\u83cc\u548c\u5927\u80a0\u6746\u83cc\u5728\u4e0d\u540c\u8868\u9762\u79cd\u690d\u7684\u6d53\u5ea6\u4e3a 107 CFU\/mL\uff1b<\/p>\n

(D) \u91d1\u8461\u83cc\u548c\u5927\u80a0\u6746\u83cc\u4ece\u4e0d\u540c\u8868\u9762\u5206\u79bb\u540e\u518d\u57f9\u517b\u4e8e\u743c\u8102\u7cd6\uff1b<\/p>\n

(E) \u5bf9\u7ec6\u83cc\u7ec6\u80de\u819c\u7684\u901a\u900f\u6027ONPG\u6c34\u89e3\u6cd5\u6d4b\u5b9a\uff1b<\/p>\n

(F)\u4e0d\u540c\u6837\u54c1\u5904\u7406\u5927\u80a0\u6746\u83cc\u548c\u91d1\u9ec4\u8272\u8461\u8404\u7403\u83cc\u7684\u86cb\u767d\u8d28\u6e17\u6f0f\u5206\u6790\u548c(G)ATP\u6c34\u5e73\uff1b<\/p>\n

\u8bef\u5dee\u6761\u8868\u793a\u5747\u503c\u00b1 \u6807\u51c6\u5dee: *P < 0.05 and ***P < 0.001 (t\u68c0\u9a8c)<\/p>\n

\u56fe5 \u6750\u6599\u7684\u6297\u83cc\u6027\u6d4b\u8bd52<\/strong><\/p>\n

\"\"<\/p>\n

(A) \u901a\u8fc7\u51cf\u5c11\u7684\u767e\u5206\u6bd4\u6765\u8868\u793a\u7684Ti-ZnOs\/PDA\/RGDC\u548cTi-ZnO\/PDA\/RGDC\u7684\u6297\u83cc\u6027\uff1b<\/p>\n

\u91d1\u8461\u83cc\u548c\u5927\u80a0\u6746\u83cc\u4ece\u4e0d\u540c\u8868\u9762\u5206\u79bb\u540e\u518d\u57f9\u517b\u4e8e\u743c\u8102\u7cd6\uff1b<\/p>\n

(B)Ti-ZnOs\/PDA\/RGDC\u548cTi-ZnO\/ PDA\/RGDC\u7684\u7d2f\u79ef\u950c\u79bb\u5b50\u91ca\u653e\u66f2\u7ebf\uff1b<\/p>\n

(C) Ti, Ti-ZnOs\/PDA\/RGDC\u548cTi-ZnO\/PDA\/RGDC\u7684ESR\u8c31\uff1b<\/p>\n

(D) \u91d1\u8461\u83cc\u548c\u5927\u80a0\u6746\u83cc\u5904\u7406\u4e8eTi, Ti-ZnOs\/PDA\/RGDC\u548cTi-ZnO\/ PDA\/RGDC TEM\u8868\u9762\u540e\u7684\u8d85\u8584\u5207\u7247\u7535\u955c\u56fe\u50cf(\u7ea6 70 nm) \u548c\u5bf9\u5e94\u7684EDS\u8c31 (\u6bd4\u4f8b\u5c3a = 500 nm). \u8bef\u5dee\u6761\u8868\u793a\u5747\u503c\u00b1 \u6807\u51c6\u5dee: *P < 0.05 and ***P < 0.001 (t\u68c0\u9a8c)<\/p>\n

\u56fe6 \u6750\u6599\u5728\u4f53\u5916\u7684\u6210\u9aa8\u6027\u80fd\u6d4b\u5b9a<\/strong><\/p>\n

\"\"<\/p>\n

(A) \u5bf9\u57f9\u517b\u4e0e\u4e0d\u540c\u6837\u672c24\u5c0f\u65f6\u7684MC3T3-El\u7ec6\u80de\u8fdb\u884c\u7684F-actin\u67d3\u8272(\u7eff\u8272) \u548c\u7ec6\u80de\u6838\u67d3\u8272 (\u84dd\u8272) (\u6bd4\u4f8b\u5c3a = 50 \u03bcm)\uff1b<\/p>\n

(B) 1\uff0c3\uff0c7\u5929\u7ecfMTT\u6cd5\u5bf9\u4e0d\u540c\u8868\u9762\u7ec6\u80de\u5b58\u6d3b\u7387\u7684\u6d4b\u5b9a\uff1b<\/p>\n

(C) 1\uff0c3\uff0c7\u5929\u5bf9\u4e0d\u540c\u8868\u9762\u7ec6\u80de\u78b1\u6027\u78f7\u9178\u9176\u6d3b\u6027\u7684\u6d4b\u5b9a\uff1b<\/p>\n

(D)7\u5929\u548c14\u5929\u7684\u831c\u7d20\u7ea2\u67d3\u8272\u5b9a\u91cf\u5206\u6790 \uff1b<\/p>\n

7\u5929\u548c14\u5929\u4e0d\u540c\u6837\u672c\u6210\u9aa8\u76f8\u5173\u57fa\u56e0(E) ALP, (F) RUNX2\u548c(G) OCN \u7684\u5b9a\u91cf\u5206\u6790<\/p>\n

\u8bef\u5dee\u6761\u8868\u793a\u5747\u503c\u00b1 \u6807\u51c6\u5dee: *P < 0.05 and ***P < 0.001 (t\u68c0\u9a8c)<\/p>\n

\u56fe7 H&E\u67d3\u8272(\u6bd4\u4f8b\u5c3a = 50 \u03bcm) and Giemsa\u67d3\u8272 (\u6bd4\u4f8b\u5c3a = 5 \u03bcm) \u56fe\u50cf\u663e\u793a\u672f\u540e2\u5468\u548c4\u5468\u8f6f\u7ec4\u7ec7\u548c\u9aa8\u7ec4\u7ec7\u7684\u611f\u67d3\u60c5\u51b5<\/strong><\/p>\n

\"\"<\/p>\n

\u56fe8 \u6750\u6599\u5728\u4f53\u5185\u7684\u6210\u9aa8\u6027\u80fd\u6d4b\u5b9a<\/strong><\/p>\n

\"\"<\/p>\n

(A) Micro-CT \u663e\u793a\u672f\u540e\u56db\u5468\u5154\u80a1\u9aa8\u4e2dTi\u548cTi-ZnO\/PDA\/RGDC\u690d\u5165\u7269\u5468\u56f4\u65b0\u9aa8\u5f62\u6210\u76842D\u548c3D\u56fe\u50cf\uff1b<\/p>\n

(B) \u5bf9\u9aa8\u91cd\u5efa\u7684micro-CT 3D\u56fe\u50cf\u5b9a\u91cf\u5206\u6790\uff1b<\/p>\n

(C) VG\u67d3\u8272\u663e\u793a\u7684\u9aa8-\u690d\u5165\u7269\u8868\u9762\u7684\u7ec4\u7ec7\u5b66\u7279\u5f81(\u6bd4\u4f8b\u5c3a = 200 \u548c 100 \u03bcm)\uff1b<\/p>\n

(D) \u901a\u8fc7\u7ec4\u7ec7\u5b66\u6d4b\u5b9a\u7684\u65b0\u9aa8\u533a\u57df\u6bd4\u4f8b\u548c\u9aa8-\u690d\u5165\u7269\u63a5\u89e6The error bars indicate means \u00b1 standard deviations: *P < 0.05, **P < 0.05, and ***P < 0.001 (t test)<\/p>\n

\u8bef\u5dee\u6761\u8868\u793a\u5747\u503c\u00b1 \u6807\u51c6\u5dee: *P < 0.05 and ***P < 0.001 (t\u68c0\u9a8c)<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u7814\u7a76\u4eba\u5458\u63d0\u51fa\u4e86\u4e00\u79cd\u5168\u65b0\u7684\u690d\u5165\u7269\u8868\u9762\u590d\u5408\u6750\u6599\u6c27\u5316\u950c\/\u805a\u591a\u5df4\u80fa\/\u7cbe\u6c28\u9178\u7518\u6c28\u9178\u5929\u51ac\u6c28\u9178\u534a\u80f1\u6c28\u9178-\u534a\u80f1\u6c28\u9178\u7eb3\u7c73\u68d2\uff0c\u901a\u8fc7\u5176\u9009\u62e9\u6027\u7269\u7406\u7a7f\u523a\u548c\u751f\u7269\u529f\u80fd\u5316\u6765\u5e73\u8861\u7ec6\u83cc-\u6210\u9aa8\u7ec6\u80de\u7ade\u4e89\uff0c\u80fd\u591f\u6709\u6548\u7684\u6291\u5236\u7ec6\u83cc\u540c\u65f6\u964d\u4f4e\u6bd2\u6027\u5e76\u63d0\u9ad8\u6210\u9aa8\u3002\u8fd9\u9879\u5de5\u4f5c\u63d0\u4f9b\u4e86\u4e00\u79cd\u690d\u5165\u7269\u8868\u9762\u7684\u8bbe\u8ba1\u7b56\u7565\uff0c\u4f7f\u5f97\u79cd\u690d\u4f53\u540c\u65f6\u62e5\u6709\u7406\u60f3\u7684\u9aa8\u6574\u5408\u80fd\u529b\u548c\u6297\u611f\u67d3\u80fd\u529b\u3002\u8fd9\u5c06\u5728\u9aa8\u79d1\u548c\u53e3\u8154\u79d1\u4e2d\u5177\u6709\u5de8\u5927\u7684\u5e94\u7528\u6f5c\u529b\u3002<\/p>\n

\u6587\u732e\u4fe1\u606f\uff1a<\/strong>Li J, Tan L, Liu X, et al. Balancing Bacteria-Osteoblasts Competition through Selective Physical Puncture and Biofunctionalization of ZnO\/Polydopamine\/Arginine-Glycine-Aspartic Acid-Cysteine Nanorods[J]. ACS nano, 2017.<\/p>\n

\u3010\u56e2\u961f\u4ecb\u7ecd\u3011<\/strong><\/p>\n

\u5929\u6d25\u5927\u5b66\u4e0e\u6e56\u5317\u5927\u5b66\u751f\u7269\u6750\u6599\u8054\u5408\u5b9e\u9a8c\u5ba4\uff0c\u76ee\u524d\u4e3b\u8981\u81f4\u529b\u4e8e\u751f\u7269\u6750\u6599\u7279\u522b\u662f\u533b\u7528\u690d\u5165\u4f53\u5305\u62ec\u949b\u5408\u91d1\u6750\u6599\u7684\u8868\u9762\u529f\u80fd\u5316\u6539\u6027\uff0c\u4f8b\u5982\u63d0\u9ad8\u8868\u9762\u7684\u539f\u4f4d\u6297\u83cc\u6027\u80fd\u548c\u957f\u671f\u7684\u9884\u9632\u7ec6\u83cc\u611f\u67d3\u529f\u80fd\uff0c\u540c\u65f6\u8c03\u63a7\u8868\u9762\u7ec6\u80de\u884c\u4e3a\uff0c\u4fc3\u8fdb\u7ec4\u7ec7\u518d\u751f\u3002<\/p>\n

\u56e2\u961f\u6240\u53d1\u8868\u7684\u5173\u4e8e\u6297\u83cc\u548c\u7ec4\u7ec7\u4fee\u590d\u4e3b\u9898\u7cfb\u5217\u6587\u7ae0\uff1a<\/strong><\/p>\n

ACS Nano, DOI: 10.1021\/acsnano.7b05620\uff0c 2017<\/p>\n

ACS Nano, 2017, 11 (9), pp 9010\u20139021<\/p>\n

ACS Applied Materials and Interfaces, DOI: 10.1021\/acsami.7b10818\uff0c2017<\/p>\n

ACS Biomater. Sci. Eng. 2017, 3, 816\u2212825<\/p>\n

Materials Science and Engineering C 79 (2017) 629\u2013637<\/p>\n

Materials & Design 130 (2017) 403\u2013412<\/p>\n

ACS Applied Materials and Interfaces, vol. 9, no. 31, pp. 26417 \u2013 26428 (2017).<\/p>\n

Applied Surface Science 400 (2017) 14\u201323<\/p>\n

ACS Appl. Mater. Interfaces, 2017, 9 (22), pp 19248\u201319257<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u751f\u7269\u6750\u6599\u7ec4\u5b59\u82d7\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n

\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c\u70b9\u6211\u52a0\u5165\u6750\u6599\u4eba\u7f16\u8f91\u90e8<\/a>\u3002\u53c2\u4e0e\u751f\u7269\u6750\u6599\u8bdd\u9898\u8ba8\u8bba\u6216\u4e86\u89e3\u751f\u7269\u6750\u6599\u5c0f\u7ec4\u62db\u52df\u8be6\u60c5\uff0c\u8bf7\u52a0\u5165\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u4ea4\u6d41\u7fa4\uff08124806506\uff09\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n

\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1aRDD-2011-CHERISH , \u4efb\u4e39\u4e39\uff0c\u6211\u4eec\u4f1a\u9080\u8bf7\u5404\u4f4d\u8001\u5e08\u52a0\u5165\u4e13\u5bb6\u7fa4\u3002<\/p>\n

\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a\u6d4b\u8bd5\u8c37<\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u9aa8\u79d1\u624b\u672f\u540e\u6709\u91cf\u5927\u5e76\u53d1\u75c7\uff0c\u5373\u611f\u67d3\u548c\u4e0d\u5145\u5206\u7684\u9aa8\u6574\u5408\uff0c\u5e76\u56e0\u6b64\u5bfc\u81f4\u79cd\u690d\u4f53\u677e\u52a8\u3001\u9aa8\u6298\u7578\u5f62\u6108\u5408\u6216\u4e0d\u6108\u5408\u4ee5\u53ca\u690d\u5165\u5931\u8d25\u3002\u611f\u67d3\u901a\u5e38\u662f\u7531\u4e8e\u79cd\u690d\u4f53\u8868\u9762\u7ec6\u83cc\u7c98\u9644\u548c\u751f\u7269\u819c\u5f62\u6210\u3002…<\/p>\n","protected":false},"author":721,"featured_media":110372,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[75],"class_list":["post-110369","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-biomaterial"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/110369"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/721"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=110369"}],"version-history":[{"count":10,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/110369\/revisions"}],"predecessor-version":[{"id":111019,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/110369\/revisions\/111019"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/media\/110372"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=110369"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=110369"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=110369"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}