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\u8fd1\u65e5\uff0c\u4e4c\u5f97\u52d2\u652f\u5927\u5b66Wigard P. Kloosterman\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u56e2\u961f\u4f7f\u7528MinION\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u4eea\u548c\u4e00\u79cd\u65b0\u7684\u8ba1\u7b97\u6d41\u7a0b-NanoSV\u5206\u6790\u4e86\u4e24\u540d\u5148\u5929\u6027\u5f02\u5e38\u60a3\u8005\u7684\u57fa\u56e0\u7ec4\u3002\u7814\u7a76\u53d1\u73b0\u7eb3\u7c73\u5b54\u8bfb\u957f\u76f8\u6bd4\u4e8e\u8bfb\u77ed\u5728\u68c0\u6d4b\u67d3\u8272\u4f53\u91cd\u6392\u65b9\u9762\u7565\u5360\u4f18\u52bf\uff0c\u540c\u65f6\u8bfb\u957f\u4e5f\u80fd\u591f\u6709\u6548\u5730\u8c03\u6574\u9057\u4f20\u53d8\u5f02\uff0c\u53ef\u4ee5\u5229\u7528\u8fd9\u4e9b\u9057\u4f20\u53d8\u5f02\u6765\u786e\u5b9a\u6240\u6709\u67d3\u8272\u4f53\u91cd\u6392\u65ad\u70b9\u7684\u4eb2\u672c\u6765\u6e90\u5e76\u89e3\u6790\u8fd9\u4e9b\u590d\u6742\u91cd\u6392\u7684\u7ed3\u6784\u3002\u53e6\u5916\uff0c\u5168\u57fa\u56e0\u7ec4\u76d1\u6d4b\u9057\u4f20\u6027SVs\u63ed\u793a\u4e86\u65b0\u7684\u53d8\u79cd\uff0c\u5728\u8bfb\u77ed\u6570\u636e\u7ec4\u4e2d\u7f3a\u5931\uff0c\u5176\u4e2d\u5f88\u5927\u4e00\u90e8\u5206\u662f\u9006\u8f6c\u5f55\u8f6c\u5ea7\u5b50\u63d2\u5165\u3002\u76f8\u5173\u6210\u679c\u4ee5\u9898\u4e3a\u201cMapping and phasing of structural variation in patient genomes using nanopore sequencing<\/strong>\u201d\u53d1\u8868\u5728\u4e86Nature Communications<\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

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\"\"<\/p>\n

a\uff09\u60a3\u80051\u548c\u60a3\u80052\u7684Circos\u56fe<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

a\uff09\u76f8\u4f4d\u5757\u957f\u5ea6\u7684\u5206\u5e03<\/p>\n

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\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

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\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Mapping and phasing of structural variation in patient genomes using nanopore sequencing<\/a>\uff08Nat.Commun,2017,DOI:10.1038\/s41467-017-01343-4\uff09<\/p>\n

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