{"id":148853,"date":"2018-08-05T14:00:15","date_gmt":"2018-08-05T06:00:15","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=148853"},"modified":"2018-08-02T21:14:48","modified_gmt":"2018-08-02T13:14:48","slug":"adv-mater-%e5%b0%81%e9%9d%a2-%e6%96%b0%e5%9e%8b%e7%ba%b3%e7%b1%b3%e8%8d%af%e7%89%a9%e5%9c%a8%e8%82%bf%e7%98%a4%e5%86%85%e6%b0%a7%e5%8c%96%e8%bf%98%e5%8e%9f-%e9%85%b6%e5%8f%8c%e9%87%8d%e5%93%8d","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=148853","title":{"rendered":"Adv. Mater. \u5c01\u9762: \u65b0\u578b\u7eb3\u7c73\u836f\u7269\u5728\u80bf\u7624\u5185\u6c27\u5316\u8fd8\u539f\/\u9176\u53cc\u91cd\u54cd\u5e94\u91ca\u653eNO\u5b9e\u73b0\u7279\u5f02\u6027\u3001\u9ad8\u6548\u4f4e\u6bd2\u764c\u75c7\u6cbb\u7597"},"content":{"rendered":"<p><strong>\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n<p>\u7531\u4e8e\u5e38\u89c4\u7684\u5316\u5b66\u6cbb\u7597\u8bd5\u5242\u5b58\u5728\u975e\u7279\u5f02\u6027\u5206\u5e03\u3001\u751f\u7269\u5229\u7528\u5ea6\u5dee\u3001\u8840\u6db2\u6e05\u9664\u5feb\u901f\u548c\u751f\u7406\u73af\u5883\u4e2d\u6eb6\u89e3\u6027\u5dee\u7684\u7f3a\u70b9\uff0c\u56e0\u6b64\u836f\u7269\u5b66\u5bb6\u81f4\u529b\u4e8e\u7814\u7a76\u5728\u4f53\u5185\u4ee3\u8c22\u65e0\u6d3b\u6027\u7684\u5171\u4ef7\u5408\u7269\u524d\u4f53\u836f\u7269\uff0c\u901a\u8fc7\u4e3b\u8981\u5b58\u5728\u4e8e\u764c\u7ec6\u80de\u4e2d\u7684\u4e00\u4e9b\u7279\u5b9a\u9176\u6216\u5916\u52a0\u50ac\u5316\u5242\u7684\u4f5c\u7528\u4ee5\u91ca\u653e\u836f\u7269\u6d3b\u6027\u6210\u5206\u3002\u524d\u4f53\u836f\u7269\u662f\u4e00\u79cd\u80fd\u591f\u5728\u7279\u5b9a\u73af\u5883\u4e0b\u91ca\u653e\u751f\u7269\u6d3b\u6027\u7ec4\u5206\u7684\u836f\u7269\uff0c\u5df2\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u6297\u80bf\u7624\u836f\u7269\u7684\u7814\u7a76\u4e2d\u3002\u4e00\u6c27\u5316\u6c2e\uff08NO\uff09\u4e5f\u662f\u5176\u4e2d\u4e00\u79cd\uff0c\u5728\u9ad8\u6d53\u5ea6\u65f6\u80fd\u591f\u6709\u6548\u5730\u6291\u5236\u80bf\u7624\u7ec6\u80de\u751f\u957f\u3001\u5f15\u8d77\u7ec6\u80de\u51cb\u4ea1\uff0c\u4ece\u800c\u8868\u73b0\u51fa\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u56e0\u6b64\uff0c\u80fd\u591f\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7279\u5f02\u6027\u91ca\u653eNO\u7684\u524d\u4f53\u836f\u7269\u5177\u6709\u5de8\u5927\u7684\u7814\u7a76\u548c\u5e94\u7528\u4ef7\u503c\u3002\u7136\u800c\uff0c\u76ee\u524d\u7684NO\u524d\u836f\u4ecd\u7136\u5b58\u5728\u6613\u88ab\u5feb\u901f\u6e05\u9664\u3001\u8fc7\u65e9\u964d\u89e3\u548c\u6bd2\u526f\u4f5c\u7528\u5927\u7684\u7f3a\u70b9\u3002\u800c\u7eb3\u7c73\u836f\u7269\u7684\u80bf\u7624\u9776\u5411\u9012\u9001\u548c\u80bf\u7624\u5185\u523a\u6fc0\u6027\u836f\u7269\u91ca\u653e\u88ab\u8ba4\u4e3a\u5728\u89e3\u51b3\u8fd9\u4e9b\u95ee\u9898\u65b9\u9762\u5177\u6709\u5f88\u5927\u7684\u6f5c\u529b\u3002\u56e0\u6b64\uff0c\u5229\u7528\u80bf\u7624\u5fae\u73af\u5883\u4e0e\u6b63\u5e38\u7ec4\u7ec7\u5728pH\u503c\u3001\u9176\u3001\u6c27\u5316\u8fd8\u539f\u7535\u52bf\u7b49\u65b9\u9762\u5b58\u5728\u7684\u5dee\u5f02\uff0c\u8bbe\u8ba1\u5177\u6709\u523a\u6fc0\u54cd\u5e94\u91ca\u653e\u836f\u7269\u7279\u6027\u7684\u667a\u80fd\u7eb3\u7c73\u836f\u7269\u5df2\u6210\u4e3a\u76ee\u524d\u7814\u7a76\u7684\u70ed\u70b9\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c<strong>\u534e\u4e1c\u7406\u5de5\u5927\u5b66\u7684\u674e\u6c38\u751f\u6559\u6388\u548c\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u7684\u9ec4\u5f20\u5efa\u6559\u6388\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u62a5\u9053\u4e86\u4e00\u79cd\u65b0\u578b\u7684\u4ee5\u542b\u6709\u4e8c\u786b\u952e\u7684\u6709\u673a-\u65e0\u673a\u6742\u5316\u7eb3\u7c73\u80f6\u675fPDHNs\u4e3a\u8f7d\u4f53\u7684\u7eb3\u7c73\u836f\u7269\uff08QM-NPQ @ PDHNs\uff09\uff0c\u901a\u8fc7\u5305\u8f7d\u5177\u6709\u9176\u54cd\u5e94\u7684\u65b0\u578bNO\u524d\u836fNPQ\uff0c\u4f7f\u5f97QM-NPQ @ PDHNs\u5177\u6709\u6c27\u5316\u8fd8\u539f\/\u9176\u53cc\u91cd\u54cd\u5e94\u91ca\u653eNO\u3002\u8be5\u7eb3\u7c73\u836f\u7269\u5f88\u597d\u7684\u907f\u514dNO\u63d0\u524d\u91ca\u653e\uff0c\u63d0\u9ad8NO\u524d\u836f\u5728\u8840\u6db2\u5faa\u73af\u4e2d\u7684\u751f\u7406\u7a33\u5b9a\u6027\uff1b\u80bf\u7624\u7ec6\u80de\u4e2d\u8fc7\u91cf\u8868\u8fbe\u7684\u8c37\u80f1\u7518\u80bdGSH\u548c\u8c37\u80f1\u7518\u80bd\u8f6c\u79fb\u9176GST\u03c0\u53ef\u4ee5\u6fc0\u6d3bNPQ\u91ca\u653eNO\uff0c\u4ee5\u5b9e\u73b0\u7279\u5f02\u6027\u6740\u4f24\u80bf\u7624\u7ec6\u80de\uff0c\u4e0d\u5f71\u54cd\u4f53\u5185\u7684\u6b63\u5e38\u5668\u5b98\uff0c\u4ece\u800c\u5b9e\u73b0\u9ad8\u6548\u3001\u4f4e\u6bd2\u7684\u764c\u75c7\u6cbb\u7597\u3002\u6b64\u9879\u7814\u7a76\u5c55\u793a\u4e86\u5177\u6709\u80bf\u7624\u5185\u6c27\u5316\u8fd8\u539f\/\u9176\u53cc\u91cd\u54cd\u5e94\u91ca\u653eNO\u7684\u7eb3\u7c73\u836f\u7269\u7528\u4e8e\u80bf\u7624\u7279\u5f02\u6027\u548c\u9ad8\u6548\u6cbb\u7597\u764c\u75c7\u7684\u8303\u4f8b\u3002\u7814\u7a76\u6210\u679c\u4ee5\u9898\u4e3a<strong>\u201cDual Intratumoral Redox\/Enzyme -Responsive NO-Releasing Nanomedicine for the Specifc, High-Effcacy, and Low-Toxic Cancer Therapy\u201d<\/strong>\u53d1\u5e03\u5728\u56fd\u9645\u8457\u540d\u671f\u520a<strong>Adv. Mater.<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u672c\u6587\u7b2c\u4e00\u4f5c\u8005\u4e3a\u534e\u4e1c\u7406\u5de5\u5927\u5b66\u7684\u8d3e\u6653\u535a\u535a\u58eb<\/strong>\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001QM-NPQ@PDHNs\u7684\u5236\u5907\u548c\u4f5c\u7528\u673a\u5236\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-148204\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/1.webp_-1.jpg\" alt=\"\" width=\"600\" height=\"364\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/1.webp_-1.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/1.webp_-1-300x182.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><\/p>\n<p>\uff08a\uff09 QM-NPQ @ PDHNs\u7684\u5236\u5907\u793a\u610f\u56fe\uff1b<\/p>\n<p>\uff08b\uff09 NPQ \u548cQM-2\u7684\u5316\u5b66\u7ed3\u6784\uff1b<\/p>\n<p>\uff08c\uff09 HCC\u80de\u5185\u8fc7\u8868\u8fbe\u7684GSH\u548cGST\u03c0\u4f5c\u7528\u4e0bQM-NPQ@PDHNs\u7684\u6cbb\u7597\u673a\u5236\u3002<\/p>\n<p><strong>\u56fe\u4e8c\u3001QM-NPQ @ PDHNs\u7684\u7406\u5316\u8868\u5f81\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-148205\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/2-86.jpg\" alt=\"\" width=\"600\" height=\"368\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/2-86.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/2-86-300x184.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><\/p>\n<p>\uff08a\uff09 PDHNs\u7684TEM\u56fe\uff1b<\/p>\n<p>\uff08b\uff09 PDHNs\u7684\u5143\u7d20\u6620\u5c04\u56fe\u50cf\uff1b<\/p>\n<p>\uff08c\uff09 QM-NPQ@PDHNs\u7684\u5438\u6536\u5149\u8c31\u548c\u8367\u5149\u5149\u8c31\uff1b<\/p>\n<p>\uff08d\uff09 \u4e0d\u540c\u6d53\u5ea6\u7684GSH\u5728\u6c34\u548cPBS\u4e2dPDHNs\u7684DLS\uff1b<\/p>\n<p>\uff08e-f\uff09 PDHNs\u572810\u00d710-3M GSH\u7684PBS\u4e2d\u5b75\u80b21d\u548c7d\u7684TEM\uff1b<\/p>\n<p>\uff08g\uff09\u785d\u9178\u76d0\/\u4e9a\u785d\u9178\u76d0\u6d4b\u5b9aQM-NPQ@PDHNs\uff0840\u00d710<sup>-6<\/sup> M NPQ\uff09\u5728\u4f53\u5916\u54cd\u5e94\u4e0d\u540c\u6d53\u5ea6\u7684GST\u03c0\u548c10\u00d710<sup>-3<\/sup> M GSH\u5728\u542b\u67095\uff05DMSO\u7684PBS\u4e2dNO\u7684\u91ca\u653e\u3002<\/p>\n<p><strong>\u56fe\u4e09\u3001QM-NPQ @ PDHNs\u7684\u7ec6\u80de\u5b9e\u9a8c\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-148206\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/3.webp_-2.jpg\" alt=\"\" width=\"600\" height=\"429\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/3.webp_-2.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/3.webp_-2-300x215.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><\/p>\n<p>\uff08a\uff09 NPQ\u3001NPQ@PDHNs\u548cQM-NPQ@PDHNs\u5206\u522b\u4e0eSMMC-7721\u3001Bel-7402\u548cLO2\u7ec6\u80de\u5b75\u80b26 h\u540e\u7ec6\u80de\u6d41\u5f0f\u5206\u6790\uff1b<\/p>\n<p>\uff08b\uff09 NPQ\u548cQM-NPQ@PDHNs\u5b75\u80b2\u7684SMMC-7721\u7ec6\u80de\u4e2dNO-DAF\u884d\u751f\u8367\u5149\u5f3a\u5ea6\u548cQM-2\u8367\u5149\u5f3a\u5ea6\u968f\u65f6\u95f4\u53d8\u5316\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08c\uff09 \u4e0d\u540c\u65f6\u95f4\u7684NPQ\u3001NPQ@PDHNs\u548cQM-NPQ@PDHNs\u5bf9SMMC-7721\u3001Bel-7402\u548cLO2\u7ec6\u80de\u7684IC50\u503c\uff1b<\/p>\n<p>\uff08d\uff09 QM-NPQ@PDHNs\u5b75\u80b2SMMC-7721\u7ec6\u80de6 h\u540e\u7684CLSM\u56fe\u3002<\/p>\n<p><strong>\u56fe\u56db\u3001QM-NPQ @ PDHNs\u7684\u5c0f\u9f20\u4f53\u5185\u8367\u5149\u6210\u50cf\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-148207\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/4.webp_-1.jpg\" alt=\"\" width=\"600\" height=\"633\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/4.webp_-1.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/4.webp_-1-284x300.jpg 284w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><\/p>\n<p>\uff08a\uff09 \u9759\u8109\u6ce8\u5c04QM-NPQ@PDHNs 24 h\u540e(\u6ce8\u5c04\u5242\u91cf\u4e3a10 mg\/kg\u7684NPQ)\u8377\u7624\u5c0f\u9f20\u76843D\u8367\u5149\u56fe\u50cf\uff1b<\/p>\n<p>\uff08b\uff09 \u9759\u8109\u6ce8\u5c04QM-NPQ@PDHNs 24 h\uff08\u4ece\u4e0a\u5230\u4e0b\uff1a\u5fc3\u810f\u3001\u809d\u810f\u3001\u813e\u810f\u3001\u80ba\u810f\u3001\u80be\u810f\u548c\u80bf\u7624\uff09\u7684\u5668\u5b98\u79bb\u4f53\u8367\u5149\u56fe\u50cf\uff1b<\/p>\n<p>\uff08c\uff09 QM-NPQ@PDHNs\u5728\u6ce8\u5c04\u540e24 h\u5904\u6b7b\u5c0f\u9f20\u7684\u80bf\u7624\u548c\u5185\u810f\u5668\u5b98\u7684\u603b\u8367\u5149\u5f3a\u5ea6\u548c\u5e73\u5747\u8367\u5149\u5f3a\u5ea6\u3002<\/p>\n<p><strong>\u56fe\u4e94\u3001QM-NPQ @ PDHNs\u7684\u5c0f\u9f20\u4f53\u5185\u5b9e\u9a8c\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-148208\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/5.webp_-2.jpg\" alt=\"\" width=\"600\" height=\"626\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/5.webp_-2.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/07\/5.webp_-2-288x300.jpg 288w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><\/p>\n<p>\uff08a\uff09 \u9759\u8109\u6ce8\u5c04QM-NPQ @ PDHNs\u7684\u8840\u6db2\u5faa\u73af\u66f2\u7ebf\u548c\u8840\u6db2\u4e2d\u7684\u8367\u5149\u5f3a\u5ea6\uff1b<\/p>\n<p>\uff08b\uff09 ln\uff08I<sub>610<\/sub>\uff09-T\u5173\u7cfb\u4ece\u8840\u6db2\u5faa\u73af\u66f2\u7ebf\u9759\u8109\u6ce8\u5c04QM-NPQ @ PDHNs\u7684\u6d88\u9664\u7387\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08c\uff09 \u9759\u8109\u6ce8\u5c0420 mg\/kg NPQ\u7684NPQ\u548cQM-NPQ @ PDHNs\u540e\u5e73\u5747\u6536\u7f29\u538b\uff08\u0394MSBP\uff09\u7684\u53d8\u5316\uff1b<\/p>\n<p>\uff08d\uff09 NPQ\u548cQM-NPQ @ PDHNs\u5904\u740621 d\u540e\u4ece\u52a8\u7269\u5207\u9664\u6240\u5f97\u80bf\u7624\uff1b<\/p>\n<p>\uff08e\uff09 \u4e94\u7ec4\u3001\u6bcf\u7ec4\u516b\u53ea\u5c0f\u9f20\u7684\u80bf\u7624\u5757\uff0c\u6bcf\u4e2a\u67f1\u72b6\u56fe\u4ee3\u8868\u5e73\u5747\u503c\u00b1S.D\uff1b<\/p>\n<p>\uff08f\uff09 \u63a5\u79cdSMMC-7721\u7ec6\u80de\u7684\u88f8\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u7684\u53d8\u5316\uff08\u6bcf2 d\u6d4b\u91cf\u548c\u8ba1\u7b97\u4e00\u6b21\uff09\uff1b<\/p>\n<p>\uff08g\uff09 \u6bcf2 d\u6d4b\u91cf\u88f8\u9f20\u4f53\u91cd\u7684\u53d8\u5316\u3002<\/p>\n<p>\n <strong>\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n<p>\u7814\u7a76\u4e86\u542b\u6709\u4e8c\u786b\u952e\u7684\u6709\u673a-\u65e0\u673a\u7684\u6742\u5316\u80f6\u675f(PDHNs)\u4e2d\u5305\u8f7d\u65b0\u578bNO-\u524d\u836fNPQ\u548cAIE gen QM-2\uff0c\u6210\u529f\u5236\u5907\u4e86\u5177\u6709\u80bf\u7624\u5185GSH\u3001GST\u03c0\u548c\u6c27\u5316\u8fd8\u539f\u53cc\u54cd\u5e94\u91ca\u653eNO\u7684\u65b0\u578b\u7eb3\u7c73\u836f\u7269\u3002\u5236\u5907\u7684QM-NPQ @ PDHNs\u5177\u6709\u826f\u597d\u7684\u88ab\u52a8\u80bf\u7624\u9776\u5411\u80fd\u529b\uff0c\u56e0\u6b64\u5305\u8f7d\u7684NPQ\u88ab\u6709\u6548\u5730\u8fd0\u9001\u5230\u80bf\u7624\u7ec4\u7ec7\u5904\uff0c\u800c\u80bf\u7624\u5904\u8fc7\u8868\u8fbe\u7684GSH\u8bf1\u5bfc\u4e8c\u786b\u952e\u7684\u88c2\u89e3\u91ca\u653eNPQ\u3002\u5728\u80bf\u7624\u90e8\u4f4d\u9ad8\u6d53\u5ea6\u7684GST\u03c0\u548cGSH\u50ac\u5316NPQ\u91ca\u653e\u5927\u91cfNO\u4ee5\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u3002\u4e0e\u6e38\u79bbNPQ\u836f\u7269\u76f8\u6bd4\uff0cQM-NPQ@ 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Mater., <strong>2018<\/strong>, DOI: 10.1002\/adma.201704490\uff09<\/p>\n<p><strong>\u3010\u4f5c\u8005\u7b80\u4ecb\u3011<\/strong><\/p>\n<p><strong>\u674e\u6c38\u751f\u6559\u6388<\/strong>\uff1a2010\u5e74\u5165\u9009\u6559\u80b2\u90e8\u65b0\u4e16\u7eaa\u4f18\u79c0\u4eba\u624d\u652f\u6301\u8ba1\u5212\u30012011\u5e74\u5165\u9009\u4e0a\u6d77\u5e02\u66d9\u5149\u5b66\u8005\u8ba1\u5212\u3002\u73b0\u62c5\u4efb\u534e\u4e1c\u7406\u5de5\u5927\u5b66\u56fd\u9645\u5408\u4f5c\u4e0e\u4ea4\u6d41\u5904\u5904\u957f\uff0c\u66fe\u62c5\u4efb\u534e\u4e1c\u7406\u5de5\u5927\u5b66\u6750\u6599\u5b66\u9662\u526f\u9662\u957f\uff0c\u8d1f\u8d23\u5b66\u9662\u7814\u7a76\u751f\u6559\u80b2\u5de5\u4f5c\u3002\u5df2\u5728\u56fd\u5185\u5916SCI\u5b66\u672f\u520a\u7269\u53d1\u8868\u8bba\u6587\u8fd170\u7bc7\uff0c\u4ed6\u4eba\u5f15\u75281800\u4f59\u6b21\uff0c\u5176\u4e2d\u4ee5\u7b2c\u4e00\u6216\u901a\u8baf\u4f5c\u8005J. Am. Chem. Soc., Nano Letters, Adv. Mater., Adv. Funct. Mater., Biomaterials \u7b49\u6742\u5fd7\u4e0a\u53d1\u8868\u8bba\u6587\u8fd150\u7bc7\u3001\u5355\u7bc7\u6700\u9ad8\u5f15\u7528200\u4f59\u6b21\u3002 \u7814\u7a76\u65b9\u5411\u4e3a\u7eb3\u7c73\u6750\u6599\u4e0e\u65e0\u673a\u529f\u80fd\u6750\u6599\u3002<\/p>\n<p><strong>\u4e3b\u8981\u7814\u7a76\u9886\u57df\u5305\u62ec: 1\u3001\u65b0\u578b\u7ed3\u6784\u7eb3\u7c73\u4e0e\u591a\u5b54\u590d\u5408\u6750\u6599\u7684\u5236\u5907\u4e0e\u5f62\u8c8c\u63a7\u5236\u3002 2\u3001\u6838-\u58f3\u7ed3\u6784\u7eb3\u7c73\u529f\u80fd\u6750\u6599\u7684\u5236\u5907\u53ca\u5728\u764c\u75c7\u7684\u8bca\u65ad\u3001\u836f\u7269\u7684\u9776\u5411\u4f20\u8f93\u4e0e\u6cbb\u7597\u7b49\u751f\u7269\u533b\u836f\u65b9\u9762\u7684\u5e94\u7528\u7814\u7a76\u30023\u3001\u73af\u5883\u53cb\u597d\u50ac\u5316\u4e0e\u80fd\u6e90\u751f\u4ea7\u7528\u50ac\u5316\u6750\u6599<\/strong>\u3002<\/p>\n<p><strong>\u9ec4\u5f20\u5efa\u6559\u6388<\/strong>\uff1a 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