{"id":151998,"date":"2018-08-28T06:28:10","date_gmt":"2018-08-27T22:28:10","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=151998"},"modified":"2018-08-28T09:02:35","modified_gmt":"2018-08-28T01:02:35","slug":"%e7%ba%a6%e7%bf%b0%e9%9c%8d%e6%99%ae%e9%87%91%e6%96%af%e5%a4%a7%e5%ad%a6adv-funct-mater-%ef%bc%9a%e7%8e%af%e7%b3%8a%e7%b2%be%e8%b0%83%e5%88%b6%e7%9a%84i%e5%9e%8b%e8%83%b6%e5%8e%9f%e8%9b%8b%e7%99%bd","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=151998","title":{"rendered":"\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66Adv. Funct. Mater.\uff1a\u73af\u7cca\u7cbe\u8c03\u5236\u7684I\u578b\u80f6\u539f\u86cb\u767d\u81ea\u7ec4\u88c5\u6765\u5236\u5907\u4eff\u751f\u89d2\u819c\u690d\u5165\u7269"},"content":{"rendered":"<p><strong>\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n<p>I\u578b\u80f6\u539f\u86cb\u767d\u662f\u4eba\u4f53\u5185\u6700\u5e38\u89c1\u7684\u4e00\u79cd\u86cb\u767d\uff0c\u5728\u5f88\u591a\u7ec4\u7ec7\u4e2d\u53d1\u6325\u7740\u7ed3\u6784\u57fa\u5143\u7684\u91cd\u8981\u89d2\u8272\u3002\u5728\u89d2\u819c\u4e2d\uff0c\u80f6\u539f\u86cb\u767d\u5f62\u6210\u76f4\u5f84\u7ea636\u7eb3\u7c73\u7684\u7ea4\u7ef4\uff0c\u5e76\u4e14\u7ea4\u7ef4\u8fdb\u4e00\u6b65\u5e73\u884c\u6392\u5217\u5f97\u5230\u5c42\u72b6\u7ed3\u6784\uff0c\u4ece\u800c\u6ee1\u8db3\u4e86\u575a\u56fa\u3001\u900f\u660e\u7ec4\u7ec7\u7684\u529f\u80fd\u9700\u8981\u3002\u4e34\u5e8a\u4e0a\uff0c\u5f00\u53d1\u89d2\u819c\u66ff\u4ee3\u7269\u6765\u4ee3\u66ff\u4eba\u4f53\u5668\u5b98\u79fb\u690d\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002\u76ee\u524d\u5df2\u7ecf\u6709\u57fa\u4e8e\u805a\uff08\u7532\u57fa\u4e19\u70ef\u9178\u7532\u916f\uff09\u548c\u805a\uff082-\u7f9f\u4e59\u57fa\u4e19\u70ef\u9178\u7532\u916f\uff09\u7b49\u5408\u6210\u805a\u5408\u7269\u7684\u73b0\u6210\u89d2\u819c\u66ff\u4ee3\u54c1\uff0c\u4f46\u662f\u8fd9\u4e9b\u79fb\u690d\u7269\u4e0d\u80fd\u6709\u6548\u4e0e\u5468\u56f4\u7ec4\u7ec7\u878d\u4e3a\u4e00\u4f53\u5e76\u6700\u7ec8\u4f1a\u88ab\u6392\u51fa\u773c\u5916\u3002\u6700\u8fd1\uff0c\u80f6\u539f\u86cb\u767d\u57fa\u7684\u751f\u7269\u89d2\u819c\u66ff\u4ee3\u7269\u4e5f\u5f97\u4ee5\u6210\u529f\u5408\u6210\uff0c\u76f8\u5bf9\u4e8e\u805a\u5408\u7269\u6765\u8bf4\u5b83\u4eec\u5177\u6709\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\uff0c\u7136\u800c\u7f3a\u4e4f\u7ed3\u6784\u7ec4\u7ec7\u9650\u5236\u4e86\u5176\u529f\u80fd\u7279\u6027\u3002\u56e0\u6b64\uff0c\u4ece\u5f00\u53d1\u89d2\u819c\u66ff\u4ee3\u7269\u7684\u89d2\u5ea6\u6765\u8bf4\uff0c\u83b7\u5f97\u5408\u9002\u7684\u6750\u6599\u673a\u68b0\u6027\u8d28\u4ee5\u540c\u65f6\u6ee1\u8db3\u7f1d\u5408\u548c\u89c6\u529b\u900f\u660e\u5ea6\u7684\u8981\u6c42\u4ecd\u662f\u4e00\u4e2a\u4e25\u5cfb\u7684\u6311\u6218\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c<strong>\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66<\/strong><strong>Jennifer H. Elisseeff<\/strong><strong>\u6559\u6388\u3001<\/strong><strong>Anirudha Sing<\/strong><strong>\u6559\u6388<\/strong>\u4e0e<strong>\u90ed\u743c\u7389\u6559\u6388<\/strong>\u5408\u4f5c\uff0c\u5229\u7528\u73af\u7cca\u7cbe\u5b9e\u73b0\u4e86\u80f6\u539f\u86cb\u767d\u7ea4\u7ef4\u5316\u548c\u7ea4\u7ef4\u6392\u5217\u7684\u8c03\u5236\uff0c\u6210\u529f\u5f97\u5230\u4e86\u4e00\u79cd\u9ad8\u5ea6\u900f\u660e\u4e14\u673a\u68b0\u5f3a\u5ea6\u9ad8\u7684\u80f6\u539f\u86cb\u767d\u73bb\u7483\u80f6\u79fb\u690d\u7269\uff0c\u8be5\u79fb\u690d\u7269\u5177\u6709\u6a21\u62df\u5929\u7136\u89d2\u819c\u7684\u8d85\u5fae\u7ed3\u6784\u3002\u7814\u7a76\u8868\u660e\uff0c\u73af\u7cca\u7cbe\u80fd\u591f\u4e0e\u80f6\u539f\u86cb\u767d\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\uff0c\u4ece\u800c\u5f71\u54cd\u73bb\u7483\u5316\u8fc7\u7a0b\u5e76\u4fc3\u4f7f\u80f6\u539f\u86cb\u767d\u539f\u7ea4\u7ef4\u5f62\u6210\u7247\u72b6\u7ed3\u6784\u3002\u8be5\u6210\u679c\u4ee5\u9898\u4e3a&#8221;<strong>Cyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants&#8221;<\/strong>\u53d1\u8868\u5728<strong>Advanced Functional Materials<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe<\/strong><strong>1<\/strong><strong>\u73af\u7cca\u7cbe\u8c03\u8282\u539f\u7ea4\u7ef4\u5f62\u6210\u548c\u6392\u5217<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-151999 size-full\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/1-52.jpg\" alt=\"\" width=\"600\" height=\"362\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/1-52.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/1-52-300x181.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>(a) \u73af\u7cca\u7cbe\u4e0e\u80f6\u539f\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u793a\u610f\u56fe\uff1b<\/p>\n<p>(b) 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src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/2-51.jpg\" alt=\"\" width=\"600\" height=\"479\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/2-51.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/2-51-300x240.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>(a) \u901a\u8fc7\u6df7\u5408\u7b49\u4f53\u79ef\u7684\u80f6\u539f\u86cb\u767d\u548c\u73af\u7cca\u7cbe\u7f13\u51b2\u6db2\u6765\u5236\u5907\u80f6\u539f\u86cb\u767d\u73bb\u7483\u80f6\uff0c\u8fc7\u7a0b\u6d89\u53ca\u51dd\u80f6\u5316\u3001\u5fae\u539f\u7ea4\u7ef4\u7ec4\u88c5\u4ee5\u53ca\u5728\u73bb\u7483\u5316\u8fc7\u7a0b\u4e2d\u539f\u7ea4\u7ef4\u751f\u957f\u548c\u91cd\u7ec4\uff1b<\/p>\n<p>(b) \u80f6\u539f\u86cb\u767d\u3001\u03b2\u73af\u7cca\u7cbe\/\u80f6\u539f\u86cb\u767d\u3001\u03b2\u73af\u7cca\u7cbe-\u7425\u73c0\u9170\/\u80f6\u539f\u86cb\u767d\u4ee5\u53ca\u5929\u7136\u5154\u89d2\u819c\u7684TEM\u548cSEM\u56fe\u50cf\uff1b<\/p>\n<p>(c) \u6709\u65e0\u73af\u7cca\u7cbe\u7684\u80f6\u539f\u86cb\u767d\u73bb\u7483\u80f6\u5728\u53ef\u89c1\u5149\u8c31\u8303\u56f4\u5185\u7684\u5149\u900f\u5c04\uff1b<\/p>\n<p>(d) \u6768\u6c0f\u6a21\u91cf\u548c\u65ad\u88c2\u5e94\u53d8\u6d4b\u91cf\u4ee5\u76d1\u6d4b\u73af\u7cca\u7cbe\u63ba\u5165\u540e\u73bb\u7483\u80f6\u7684\u62c9\u4f38\u6027\u80fd\uff1b<\/p>\n<p>(e) \u73af\u7cca\u7cbe\u529f\u80fd\u5316\u524d\u540e\u80f6\u539f\u86cb\u767d\u73bb\u7483\u80f6\u7684\u632f\u8361\u6d41\u53d8\u6027\u8d28\uff1b<\/p>\n<p>(f) \u5dee\u793a\u626b\u63cf\u91cf\u70ed\u6cd5\u5206\u6790\u56fe\u4ee5\u786e\u5b9a\u73af\u7cca\u7cbe\u63ba\u5165\u5bf9\u73bb\u7483\u80f6\u70ed\u7a33\u5b9a\u6027\u7684\u5f71\u54cd\u3002<\/p>\n<p><strong>\u56fe3 \u80f6\u539f\u86cb\u767d\u4e0e\u73af\u7cca\u7cbe\u95f4\u7684\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u53ca\u5176\u5bf9\u539f\u7ea4\u7ef4\u5f62\u6210\u7684\u5f71\u54cd<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-152001 size-full\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/3-51.jpg\" alt=\"\" width=\"600\" height=\"625\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/3-51.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/3-51-288x300.jpg 288w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>(a) \u5706\u4e8c\u8272\u5149\u8c31\u7528\u6765\u8bc1\u660e\u53ef\u6eb6\u6027\u80f6\u539f\u86cb\u767d\u548c\u03b2\u73af\u7cca\u7cbe\u76f8\u4e92\u4f5c\u7528\u540e\u70ed\u7a33\u5b9a\u6027\u7684\u53d8\u5316\uff1b<\/p>\n<p>(b) \u6709\u65e0\u73af\u7cca\u7cbe\u6761\u4ef6\u4e0b\u80f6\u539f\u86cb\u767d\u4e09\u87ba\u65cb\u7ed3\u6784\u7684\u5706\u4e8c\u8272\u5149\u8c31\uff1b<\/p>\n<p>(c) \u5c06\u03b2\u73af\u7cca\u7cbe\u548c\u03b2\u73af\u7cca-\u7425\u73c0\u9170\u52a0\u5165\u53ef\u6eb6\u6027\u80f6\u539f\u86cb\u767d\u540e\uff0c\u7d2b\u5916-\u53ef\u89c1\u5149\u8c31\u5438\u6536\u5cf0\u503c\u7684\u504f\u79fb\uff1b<\/p>\n<p>(d) 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\u4eff\u751f\u80f6\u539f\u86cb\u767d-\u73af\u7cca\u7cbe\u690d\u5165\u7269\u7684\u529f\u80fd\u517c\u5bb9\u6027\u548c\u624b\u672f\u4f53\u5185\u6027\u80fd<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-152002 size-full\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/4-48.jpg\" alt=\"\" width=\"600\" height=\"250\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/4-48.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2018\/08\/4-48-300x125.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>(a) \u4f53\u5916\u5154\u89d2\u819c\u4e2d\u73af\u7cca\u7cbe\/\u80f6\u539f\u86cb\u767d\u6750\u6599\u7684\u690d\u5165\u793a\u610f\u56fe\uff1b<\/p>\n<p>(b) \u901a\u8fc7\u8367\u5149\u7d20\u67d3\u8272\u89c2\u5bdf\u768472\u5c0f\u65f6\u540e\u89d2\u819c\u4e0a\u76ae\u521b\u9762\u6108\u5408\u60c5\u51b5\uff1b<\/p>\n<p>(c) \u5229\u7528H&amp;E\u7ec4\u7ec7\u5b66\u572872\u5c0f\u65f6\u89c2\u5bdf\u5230\u7684\u690d\u5165\u7269\u4e2d\u4e0a\u76ae\u7ec6\u80de\u589e\u6b96\u60c5\u51b5\uff1b<\/p>\n<p>(d) \u901a\u8fc7\u690d\u5165\u7684\u4f53\u5916\u89d2\u819c\u5207\u7247\u7684\u514d\u75ab\u7ec4\u7ec7\u5316\u5b66DAPI\uff08\u84dd\u8272\uff09\u548cK-14\uff08\u7ea2\u8272\uff09\u67d3\u8272\u6765\u5b9e\u73b0\u7ec6\u80de\u6210\u719f\u548c\u529f\u80fd\u4e0a\u76ae\u7ec6\u80de\u7684\u53ef\u89c6\u5316\uff1b<\/p>\n<p>(e) \u7528\u4e8e\u5236\u9020\u5177\u6709\u6240\u9700\u66f2\u7387\u690d\u5165\u7269\u7684\u5b9a\u5236\u6a21\u5177\uff1b<\/p>\n<p>(f) \u5177\u6709\u5065\u5eb7\u89d2\u819c\u66f2\u7387\u7684\u900f\u955c\u72b6\u03b2\u73af\u7cca\u7cbe\/\u80f6\u539f\u86cb\u767d\u89d2\u819c\u690d\u5165\u7269\uff1b<\/p>\n<p>(g) \u4f7f\u7528\u95f4\u65ad\u7f1d\u5408\u7684\u89d2\u819c\u690d\u5165\u7269\u7684\u4f53\u5185\u690d\u5165\u548c\u9644\u7740\u7684\u793a\u610f\u56fe\uff1b<\/p>\n<p>(h) 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href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/adfm.201804076\" target=\"_blank\" rel=\"noopener\">Cyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants\u00a0<\/a>\u00a0(Adv. Funct. Mater. 2018, DOI: 10.1002\/adfm.201804076)<\/strong><\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u5b66\u672f\u7ec4biotech\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u5ba1\u6838\u6574\u7406\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n<p>\u6295\u7a3f\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaokefu\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 I\u578b\u80f6\u539f\u86cb\u767d\u662f\u4eba\u4f53\u5185\u6700\u5e38\u89c1\u7684\u4e00\u79cd\u86cb\u767d\uff0c\u5728\u5f88\u591a\u7ec4\u7ec7\u4e2d\u53d1\u6325\u7740\u7ed3\u6784\u57fa\u5143\u7684\u91cd\u8981\u89d2\u8272\u3002\u5728\u89d2\u819c\u4e2d\uff0c\u80f6\u539f\u86cb\u767d\u5f62\u6210\u76f4\u5f84\u7ea636\u7eb3\u7c73\u7684\u7ea4\u7ef4\uff0c\u5e76\u4e14\u7ea4\u7ef4\u8fdb\u4e00\u6b65\u5e73\u884c\u6392\u5217\u5f97\u5230\u5c42\u72b6&#8230;<\/p>\n","protected":false},"author":7746,"featured_media":151999,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[3538,2903],"class_list":["post-151998","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-3538","tag-2903"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/151998"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/7746"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=151998"}],"version-history":[{"count":2,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/151998\/revisions"}],"predecessor-version":[{"id":152011,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/151998\/revisions\/152011"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/media\/151999"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=151998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=151998"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=151998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}