{"id":175663,"date":"2019-05-19T06:18:17","date_gmt":"2019-05-18T22:18:17","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=175663"},"modified":"2019-05-18T18:19:07","modified_gmt":"2019-05-18T10:19:07","slug":"%e9%83%91%e5%b7%9e%e5%a4%a7%e5%ad%a6%e5%bc%a0%e6%8c%af%e4%b8%ad%e6%95%99%e6%8e%88%e8%af%be%e9%a2%98%e7%bb%84nano-lett-%e8%bf%9e%e7%bb%ad%e7%bb%86%e8%83%9e%e9%97%b4%e7%ba%b3%e7%b1%b3%e9%80%92%e9%80%81","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=175663","title":{"rendered":"\u90d1\u5dde\u5927\u5b66\u5f20\u632f\u4e2d\u6559\u6388\u8bfe\u9898\u7ec4Nano Lett.:\u8fde\u7eed\u7ec6\u80de\u95f4\u7eb3\u7c73\u9012\u9001\u7cfb\u7edf\u7528\u4e8e\u589e\u5f3aROS\u8bf1\u5bfc\u7684\u6297\u80bf\u7624\u6cbb\u7597"},"content":{"rendered":"

\u3010\u5f15\u8a00<\/strong>\u3011<\/p>\n

\u6d3b\u6027\u6c27\uff08ROS\uff09\uff0c\u5305\u62ec\u5355\u7ebf\u6001\u6c27\uff081<\/sup>O2<\/sub>\uff09\u3001\u8d85\u6c27\u81ea\u7531\u57fa\uff08O2<\/sub>\u2022-<\/sup>\uff09\u3001\u7f9f\u57fa\u81ea\u7531\u57fa\uff08\u2022OH\uff09\u548c\u8fc7\u6c27\u5316\u7269\uff08O2<\/sub>2-<\/sup>\uff09\uff0c\u5728\u7ec6\u80de\u751f\u547d\u5468\u671f\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\u3002\u8f83\u4f4e\u6d53\u5ea6\u65f6\uff0cROS\u53ef\u4f5c\u4e3a\u7ec6\u80de\u5185\u7684\u5173\u952e\u4fe1\u53f7\u5206\u5b50\u4ee5\u8c03\u8282\u7ec6\u80de\u7684\u751f\u957f\u3001\u589e\u6b96\u548c\u5206\u5316\u3002\u7136\u800c\uff0c\u7ec6\u80de\u5185\u7684ROS\u5f02\u5e38\u4ea7\u751f\u5c06\u5bfc\u81f4\u8102\u8d28\u3001\u86cb\u767d\u8d28\u6216\u548cDNA\u7684\u6c27\u5316\u635f\u4f24\u3002\u6b63\u5e38\u60c5\u51b5\u4e0b\uff0c\u7ec6\u80de\u80fd\u591f\u5e73\u8861\u8fd9\u79cd\u6c27\u5316\u635f\u4f24\u4ee5\u4fdd\u62a4\u7ec6\u80de\u514d\u4e8e\u6b7b\u4ea1\u3002\u4f46\u662f\uff0c\u8fc7\u91cf\u7684ROS\u4ea7\u751f\u5c06\u6253\u7834\u8fd9\u79cd\u6c27\u5316\u5e73\u8861\uff0c\u4ece\u800c\u5bf9\u7ec6\u80de\u4ea7\u751f\u4e0d\u53ef\u9006\u7684\u6c27\u5316\u635f\u4f24\u5e76\u6700\u7ec8\u5bfc\u81f4\u7ec6\u80de\u51cb\u4ea1\u3002\u7a81\u7834ROS\u5e73\u8861\u7684\u9608\u503c\u4ee5\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u6b7b\u4ea1\u5df2\u5e7f\u6cdb\u5e94\u7528\u4e8e\u764c\u75c7\u7684\u6cbb\u7597\u3002\u5149\u52a8\u529b\u7597\u6cd5\uff08PDT\uff09\u4f5c\u4e3a\u4e00\u79cd\u4ee3\u8868\u6027\u7684\u5229\u7528ROS\u8fdb\u884c\u764c\u75c7\u6cbb\u7597\u7684\u65b9\u6cd5\uff0c\u5176\u5177\u6709\u5de8\u5927\u7684\u6297\u80bf\u7624\u6cbb\u7597\u6f5c\u529b\uff0c\u540c\u65f6\u5177\u6709\u8f83\u4f4e\u6bd2\u526f\u4f5c\u7528\uff0c\u4e14\u4e0d\u6613\u4ea7\u751f\u8010\u836f\u3002\u5c3d\u7ba1\u65e9\u5df2\u88abFDA\u6279\u51c6\u7528\u4e8e\u4e34\u5e8a\u4e0a\u764c\u75c7\u7684\u6cbb\u7597\uff0c\u4f46\u5927\u591a\u6570\u60c5\u51b5\u4e0bPDT\u4ecd\u96be\u4ea7\u751f\u8db3\u591f\u7684\u6cbb\u7597\u6548\u7387\u4ee5\u4f5c\u4e3a\u4e00\u7ebf\u7684\u764c\u75c7\u6cbb\u7597\u624b\u6bb5\u3002<\/p>\n

\u7f3a\u6c27\u4f5c\u4e3a\u8bb8\u591a\u5b9e\u4f53\u80bf\u7624\u4e2d\u5e38\u89c1\u7684\u75c5\u7406\u7279\u5f81\uff0c\u5df2\u88ab\u5e7f\u6cdb\u8ba4\u4e3a\u662fPDT\u5728\u764c\u75c7\u6cbb\u7597\u4e2d\u4e34\u5e8a\u7ed3\u679c\u6b20\u4f73\u7684\u4e3b\u8981\u539f\u56e0\u3002\u4e3a\u4e86\u89e3\u51b3\u8fd9\u4e00\u95ee\u9898\uff0c\u79d1\u7814\u5de5\u4f5c\u8005\u6295\u5165\u5927\u91cf\u7cbe\u529b\u4ee5\u7f13\u89e3\u80bf\u7624\u7ec4\u7ec7\u7684\u7f3a\u6c27\u72b6\u51b5\uff0c\u5982\u5229\u7528\u5168\u6c1f\u5316\u78b3\u4f5c\u4e3a\u6c27\u81ea\u4f9b\u5e94\u7cfb\u7edf1<\/sup><\/a>\u6216\u5e94\u7528\u50ac\u5316\u5242\u5728\u80bf\u7624\u5185\u539f\u4f4d\u4ea7\u751f\u6c272<\/sup><\/a>\u3002\u7136\u800c\uff0c\u8fd9\u4e9b\u7b56\u7565\u4ecd\u7136\u662f\u57fa\u4e8e\u590d\u6742\u7684\u5149\u654f\u6548\u5e94\u4ea7\u751fROS\u7684\u3002\u4e3a\u4e86\u8fdb\u4e00\u6b65\u6269\u5927ROS\u7684\u4ea7\u751f\uff0c\u7814\u7a76\u5de5\u4f5c\u5df2\u8bbe\u8ba1\u51fa\u4e0d\u4f9d\u8d56\u4e8eO2<\/sub>\u7684ROS\u4ea7\u751f\u7b56\u7565\u4ee5\u5b8c\u5168\u514b\u670d\u4f4e\u6c27\u8bf1\u5bfc\u7684PDT\u6297\u6027\u3002\u4f8b\u5982\uff0cQu\u7b49\u4eba\u5e94\u7528\u7eb3\u7c73\u9176\u6765\u50ac\u5316\u7ec6\u80de\u5185\u751f\u5316\u53cd\u5e94\u4ee5\u4ea7\u751fROS\uff0c\u4ece\u800c\u8bf1\u5bfc\u7f3a\u6c27\u80bf\u7624\u7ec4\u7ec7\u5185\u7684\u7ec6\u80de\u6c27\u5316\u635f\u4f243<\/sup><\/a>\u3002\u867d\u7136\u8fd9\u4e9b\u65b9\u6cd5\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u63d0\u9ad8\u4e86\u80bf\u7624\u7ec4\u7ec7\u5185\u7684ROS\u4ea7\u751f\uff0c\u4f46\u4eba\u4eec\u5e38\u5e38\u5ffd\u7565\u662f\uff0c\u80bf\u7624\u7f3a\u6c27\u533a\u57df\u5f80\u5f80\u4f4d\u4e8e\u80bf\u7624\u7684\u6df1\u5904\uff0c\u56e0\u6b64\u9759\u8109\u6ce8\u5c04\u7684\u836f\u7269\u8f7d\u4f53\u6216\u836f\u7269\u901a\u5e38\u662f\u96be\u4ee5\u63a5\u8fd1\u76844<\/sup><\/a>\u3002\u80bf\u7624\u5fae\u8840\u7ba1\u5f02\u5e38\u4ee5\u53ca\u7ec6\u80de\u5230\u8840\u7ba1\u7684\u6269\u6563\u8ddd\u79bb\u589e\u52a0\u5bfc\u81f4\u6c27\u4f9b\u5e94\u4e0d\u8db3\u7684\u540c\u65f6\uff0c\u4f7f\u836f\u7269\u6216\u7eb3\u7c73\u9897\u7c92\u4e5f\u5f88\u96be\u5230\u8fbe\u80bf\u7624\u6df1\u90e8\u7ec6\u80de\u3002\u56e0\u6b64\uff0c\u4e00\u4e2a\u7406\u60f3\u7684ROS\u6297\u80bf\u7624\u6cbb\u7597\u624b\u6bb5\u4e0d\u4ec5\u80fd\u5728\u7f3a\u6c27\u80bf\u7624\u7ec4\u7ec7\u5185\u9ad8\u6548\u7684\u4ea7\u751fROS\uff0c\u540c\u65f6\u80fd\u6709\u6548\u7684\u5c06ROS\u4ea7\u751f\u5242\u8f6c\u8fd0\u81f3\u80bf\u7624\u6df1\u90e8\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb<\/strong>\u3011<\/p>\n

\u8fd1\u65e5\uff0c\u90d1\u5dde\u5927\u5b66\u5f20\u632f\u4e2d\u6559\u6388\u8bfe\u9898\u7ec4<\/strong>\u6784\u5efa\u4e86\u4e00\u79cd\u8fde\u7eed\u6027\u7ec6\u80de\u95f4\u9012\u9001\u7684\u7eb3\u7c73\u7cfb\u7edf\uff08MFLs\/LAOOH@DOX\uff09\uff0c\u5176\u4ee5\u819c\u878d\u5408\u8102\u8d28\u4f53\u4e3a\u8f7d\u4f53\uff0c\u540c\u65f6\u5728\u5728\u8102\u8d28\u4f53\u78f7\u8102\u53cc\u5206\u5b50\u5c42\u53ca\u6c34\u6eb6\u6027\u5185\u6838\u4e2d\u5206\u522b\u5305\u8f7d\u4e9a\u6cb9\u9178\u8fc7\u6c27\u5316\u7269\uff08LAOOH\uff09\u548c\u6297\u80bf\u7624\u836f\u7269\u591a\u67d4\u6bd4\u661f\uff08DOX\uff09\u3002\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u4f5c\u8005\u9009\u7528\u4f53\u5185\u8102\u8d28\u8fc7\u6c27\u5316\u4e3b\u8981\u4ea7\u7269\u4e4b\u4e00LAOOH\u4f5c\u4e3aROS\u4ea7\u751f\u5242\uff0c\u5176\u4e3b\u8981\u662f\u4f9d\u8d56\u4e8eFe2+<\/sup>\u800c\u4e0d\u662f\u6c27\u548c\u5176\u4ed6\u5916\u90e8\u523a\u6fc0\u4ea7\u751fROS\u7684\u3002\u5f97\u76ca\u4e8e\u80bf\u7624\u7ec4\u7ec7\u7279\u6709\u7684\u5f3a\u6e17\u900f\u6027\u548c\u9ad8\u6ede\u7559\u6027\uff0cMFLs\/LAOOH@DOX\u9996\u5148\u4e0e\u8840\u7ba1\u5468\u56f4\u7684\u80bf\u7624\u7ec6\u80de\u819c\u878d\u5408\uff0c\u540c\u65f6\u9009\u62e9\u6027\u5c06LAOOH\u9012\u9001\u81f3\u8d28\u819c\uff0c\u5e76\u5728\u7ec6\u80de\u5185\u5982\u9700\u91ca\u653eDOX\u3002\u4f5c\u4e3a\u7ec6\u80de\u819c\u5929\u7136\u6210\u5206\u7684LAOOH\uff0c\u901a\u8fc7\u642d\u4e58\u7ec6\u80de\u5916\u56ca\u6ce1\u9010\u6e10\u8513\u5ef6\u5230\u90bb\u8fd1\u7ec6\u80de\uff0c\u5e76\u6700\u7ec8\u6269\u6563\u5230\u6574\u4e2a\u80bf\u7624\u3002\u7ed3\u5408\u968f\u540e\u7684\u7eb3\u7c73Fe3<\/sub>O4<\/sub>\uff0cLAOOH\u5728\u6574\u4e2a\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u80bf\u7624\u7ec6\u80de\u819c\u4e0a\u7279\u5f02\u6027\u5730\u4ea7\u751fROS\u3002\u8be5\u7814\u7a76\u4e3a\u589e\u5f3a\u57fa\u4e8eROS\u7684\u6297\u80bf\u7624\u6cbb\u7597\u7684\u6548\u7387\u63d0\u4f9b\u4e86\u4e00\u79cd\u65b0\u65b9\u6cd5\u3002\u8be5\u6210\u679c\u4ee5\u9898\u4e3a\u201cSequential Intercellular Delivery Nanosystem for Enhancing ROS-Induced Antitumor Therapy<\/strong>\u201d\u53d1\u8868\u5728Nano Lett.<\/strong>(http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31034238<\/u>)<\/u>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

Scheme 1.<\/strong>\u57fa\u4e8e<\/strong>MFLs<\/strong>\u7684\u6297\u764c\u836f\u7269\u9012\u9001\u7cfb\u7edf\u7528\u4e8e\u6cbb\u7597\u6076\u6027\u80bf\u7624\u7684\u793a\u610f\u56fe<\/strong><\/p>\n

\"\"<\/p>\n

Scheme 2.MFLs<\/strong>\u548c\u4f20\u7edf\u8102\u8d28\u4f53\uff08<\/strong>CLs<\/strong>\uff09\u7684\u7ec6\u80de\u5185\u5728\u5316\u65b9\u5f0f\u793a\u610f\u56fe<\/strong><\/p>\n

\"\"<\/p>\n

Figure 1. <\/strong>\u5236\u5242\u7684\u8868\u5f81<\/strong><\/p>\n

\"\"<\/p>\n

(a).MFLs\u7684TEM\u56fe\u50cf<\/p>\n

(b,c).MFLs\u7684\u7c92\u5f84\u548cZeta\u7535\u4f4d<\/p>\n

(d).\u4e0d\u540cpH\u4e0bLAOOH\u7684ROS\u4ea7\u751f\u80fd\u529b\u8003\u5bdf<\/p>\n

(e).DOX\u91ca\u653e\u66f2\u7ebf<\/p>\n

Figure 2.MFLs\/LAOOH<\/strong>\u5728\u7ec6\u80de\u6c34\u5e73\u4ea7\u751f<\/strong>ROS<\/strong>\u80fd\u529b\u7684\u8003\u5bdf<\/strong><\/p>\n

\"\"<\/p>\n

(a).CLSM\u68c0\u6d4bMFLs\/LAOOH\u57284T1\u7ec6\u80deROS\u4ea7\u751f\u7684\u80fd\u529b<\/p>\n

(b).\u6d41\u5f0f\u7ec6\u80de\u4eea\u5206\u6790ROS\u4ea7\u751f\u91cf<\/p>\n

Figure 3.<\/strong>\u7ec6\u80de\u5185\u5728\u5316\u65b9\u5f0f\u548c\u7ec6\u80de\u6bd2\u6027\u5206\u6790<\/strong><\/p>\n

\"\"<\/p>\n

(a). \u5229\u7528CLSM\u8003\u5bdfCLs\u548cMFLs\u7684\u5185\u5728\u5316\u65b9\u5f0f<\/p>\n

(b). 4T1\u7ec6\u80de\u7684Annexin V\/PI\u67d3\u8272<\/p>\n

Figure 4.Transwell<\/strong>\u5b9e\u9a8c<\/strong><\/p>\n

\"\"<\/p>\n

(a). Transwell\u5b9e\u9a8c\u793a\u610f\u56fe<\/p>\n

(b). CLSM\u8003\u5bdf\u4e0b\u5ba4\u7ec6\u80de\u7684\u8367\u5149\u5f3a\u5ea6\u53ca\u5176\u5206\u5e03<\/p>\n

(c). \u4e0b\u5ba4\u7ec6\u80deROS\u4ea7\u751f\u91cf\u8003\u5bdf<\/p>\n

Figure 5.MFLs<\/strong>\u5728\u4f53\u5916<\/strong>3D<\/strong>\u80bf\u7624\u7ec6\u80de\u7403\u7684\u6e17\u900f\u6027\u8003\u5bdf<\/strong><\/p>\n

\"\"<\/p>\n

(a). CLs\u548cMFLs\u57283D\u80bf\u7624\u7ec6\u80de\u7403\u5185\u7684\u6e17\u900f\u6027\u8003\u5bdf<\/p>\n

(b).\u7ecf\u4e0d\u540c\u5236\u5242\u5904\u7406\u540e\u80bf\u7624\u7ec6\u80de\u7403\u76843D\u56fe<\/p>\n

Figure 6.<\/strong>\u57fa\u4e8e<\/strong>MFLs<\/strong>\u7684\u7eb3\u7c73\u836f\u7269\u9012\u9001\u7cfb\u7edf\u5728\u6591\u9a6c\u9c7c\u80da\u80ce\u4e2d\u7684\u6e17\u900f\u80fd\u529b<\/strong><\/p>\n

\"\"<\/p>\n

(a).\u4e0d\u540c\u5236\u5242\u5904\u7406\u540e\u6591\u9a6c\u9c7c\u80da\u80ce\u7684\u8367\u5149\u5206\u5e03\u56fe<\/p>\n

(b).\u4f7f\u7528\u8d1f\u8f7dPI\u7684\u8102\u8d28\u4f53\u4ee5\u8bc4\u4f30\u6838\u5185\u9012\u9001<\/p>\n

Figure 7.<\/strong>\u4f53\u5185\u5b9e\u9a8c<\/strong><\/p>\n

\"\"<\/p>\n

(a).\u8003\u5bdf\u4e0d\u540c\u5236\u5242\u5bf94T1\u80bf\u7624\u5f02\u79cd\u79fb\u690d\u6a21\u578b\u7684\u6cbb\u7597\u6548\u679c<\/p>\n

(b).\u6cbb\u7597\u540e\u5c0f\u9f20\u5fc3\u810f\u6bd2\u526f\u4f5c\u7528\u7684\u8003\u5bdf<\/p>\n

(c).\u4f53\u5185\u8003\u5bdfCLs\u548cMFLs\u5728\u80bf\u7624\u7ec4\u7ec7\u5185\u7684\u6e17\u900f\u6027<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u5728\u8fd9\u4e2a\u7814\u7a76\u4e2d\uff0c\u4f5c\u8005\u9009\u62e9\u4e9a\u6cb9\u9178\u6c22\u8fc7\u6c27\u5316\u7269\uff08LAOOH\uff09\u4f5c\u4e3aROS\u7684\u4ea7\u751f\u8bd5\u5242\u3002\u4e0e\u5e38\u89c4\u5149\u654f\u5242\uff08PS\uff09\u76f8\u6bd4\uff0c\u5176\u4ea7\u751f\u7684ROS\u662f\u7531Fe2+\u50ac\u5316\u7684\uff0c\u5e76\u4e0d\u4f9d\u8d56\u4e8e\u6c27\u6c14\u6216\u5176\u4ed6\u5916\u90e8\u523a\u6fc0\u3002\u8003\u8651\u5230\u7f3a\u6c27\u533a\u57df\u901a\u5e38\u4f4d\u4e8e\u80bf\u7624\u6df1\u5904\u5e76\u4e14\u96be\u4ee5\u63a5\u8fd1\u7684\u4e8b\u5b9e\uff0c\u4f5c\u8005\u5f00\u53d1\u4e86\u4e00\u79cd\u57fa\u4e8e\u819c\u878d\u5408\u8102\u8d28\u4f53\u7684\u7eb3\u7c73\u9012\u9001\u4f53\u7cfb\uff0c\u4ee5\u5728\u7ec6\u80de\u95f4\u8fdb\u884c\u8fde\u7eed\u6027\u4f20\u9012\uff0c\u5176\u4e2dLAOOH\u88ab\u8d1f\u8f7d\u5230\u78f7\u8102\u53cc\u5c42\u4e2d\u540c\u65f6DOX\u88ab\u5305\u5c01\u5230MFLs\u7684\u4eb2\u6c34\u6838\u5fc3\u4e2d\uff08MFLs\/LAOOH@DOX\uff09\u3002\u6240\u5236\u5907\u7684\u7684MFLs\/LAOOH@DOX\u80fd\u591f\u9009\u62e9\u6027\u5c06LAOOH\u9012\u9001\u5230\u80bf\u7624\u7ec6\u80de\u7684\u8d28\u819c\u4e2d\uff0c\u4f34\u968f\u7740DOX\u5982\u9700\u7ec6\u80de\u5185\u91ca\u653e\u4ee5\u8bf1\u5bfc\u7ec6\u80de\u6b7b\u4ea1\u3002\u57fa\u4e8e\u7ec6\u80de\u5916\u5206\u6ccc\u56ca\u6ce1\uff08EVs\uff09\u4ecb\u5bfc\u7684\u7ec6\u80de\u95f4\u8102\u8d28\u4ea4\u6362\uff0cLAOOH\u6700\u7ec8\u9010\u6e10\u5206\u5e03\u5728\u6574\u4e2a\u80bf\u7624\u4e2d\u3002\u8fd9\u79cd\u8fde\u7eed\u7684\u7ec6\u80de\u95f4\u9012\u9001\u7cfb\u7edf\u901a\u8fc7\u540c\u65f6\u6539\u5584ROS\u4ea7\u7387\u548c\u80bf\u7624\u5206\u5e03\u6765\u63d0\u4f9b\u589e\u5f3aROS\u8bf1\u5bfc\u7684\u6297\u80bf\u7624\u529f\u6548\u3002<\/p>\n

Sequential Intercellular Delivery Nanosystem for Enhancing ROS-Induced Antitumor Therapy<\/a><\/p>\n

(Nano Lett., 2019, DOI: 10.1021\/acs.nanolett.9b00336)<\/p>\n

\u672c\u6587\u7531tt\u4f9b\u7a3f\u3002\u00a0<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n

\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaorenvip\uff0c\u6211\u4eec\u4f1a\u9080\u8bf7\u5404\u4f4d\u8001\u5e08\u52a0\u5165\u4e13\u5bb6\u7fa4\u3002\u00a0<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u6d3b\u6027\u6c27\uff08ROS\uff09\uff0c\u5305\u62ec\u5355\u7ebf\u6001\u6c27\uff081O2\uff09\u3001\u8d85\u6c27\u81ea\u7531\u57fa\uff08O2\u2022-\uff09\u3001\u7f9f\u57fa\u81ea\u7531\u57fa\uff08\u2022OH\uff09\u548c\u8fc7\u6c27\u5316\u7269\uff08O22-\uff09\uff0c\u5728\u7ec6\u80de\u751f\u547d\u5468\u671f\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\u3002\u8f83\u4f4e\u6d53\u5ea6…<\/p>\n","protected":false},"author":7336,"featured_media":175665,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[75],"class_list":["post-175663","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-biomaterial"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/175663"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/7336"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=175663"}],"version-history":[{"count":2,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/175663\/revisions"}],"predecessor-version":[{"id":175777,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/175663\/revisions\/175777"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/media\/175665"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=175663"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=175663"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=175663"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}