{"id":179259,"date":"2019-07-03T06:30:24","date_gmt":"2019-07-02T22:30:24","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=179259"},"modified":"2019-07-02T16:33:42","modified_gmt":"2019-07-02T08:33:42","slug":"%e8%a5%bf%e5%8d%97%e4%ba%a4%e9%80%9a%e5%a4%a7%e5%ad%a6%e9%b2%81%e9%9b%84%e6%95%99%e6%8e%88nanoscale%ef%bc%9a%e9%92%88%e5%af%b9%e7%9a%ae%e8%82%a4%e4%bc%a4%e5%8f%a3%e5%be%ae%e7%8e%af%e5%a2%83%e8%ae%be","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=179259","title":{"rendered":"\u897f\u5357\u4ea4\u901a\u5927\u5b66\u9c81\u96c4\u6559\u6388Nanoscale\uff1a\u9488\u5bf9\u76ae\u80a4\u4f24\u53e3\u5fae\u73af\u5883\u8bbe\u8ba1\u4eff\u8d3b\u8d1d\u591a\u529f\u80fd\u590d\u5408\u51b7\u51bb\u51dd\u80f6\u7528\u4e8e\u5168\u5c42\u76ae\u80a4\u7f3a\u635f\u4fee\u590d"},"content":{"rendered":"

\u3010\u524d\u8a00\u3011<\/strong><\/p>\n

\u76ae\u80a4\u4f5c\u4e3a\u4eba\u4f53\u6700\u5927\u7684\u5668\u5b98\uff0c\u5177\u6709\u4fdd\u62a4\u3001\u611f\u77e5\u4ee5\u53ca\u4ee3\u8c22\u7b49\u529f\u80fd\uff0c\u91cd\u5ea6\u76ae\u80a4\u7f3a\u635f\u4e25\u91cd\u5a01\u80c1\u4eba\u4eec\u7684\u5065\u5eb7\u548c\u751f\u547d\u3002\u5bf9\u4e8e\u5168\u76ae\u5c42\u7f3a\u635f\u4f24\u53e3\uff0c\u76ae\u80a4\u521b\u4f24\u4fee\u590d\u662f\u4e00\u4e2a\u975e\u5e38\u590d\u6742\u7684\u751f\u7406\u751f\u5316\u53cd\u5e94\uff0c\u6d89\u53ca\u8bf8\u591a\u7684\u52a8\u6001\u53cd\u5e94\u8fc7\u7a0b\uff0c\u5305\u62ec\u7ec6\u83cc\u5165\u4fb5\u5bfc\u81f4\u7684\u611f\u67d3\u3001\u708e\u75c7\u53cd\u5e94\u3001\u65b0\u7ec4\u7ec7\u5f62\u6210\u548c\u91cd\u5851\u7b49\u3002\u56e0\u6b64\uff0c\u4ec5\u9760\u5355\u4e00\u7684\u6750\u6599\u5df2\u7ecf\u65e0\u6cd5\u6ee1\u8db3\u4f24\u53e3\u7684\u4fee\u590d\u8981\u6c42\uff0c\u9488\u5bf9\u4f24\u53e3\u6108\u5408\u5404\u4e2a\u9636\u6bb5\u7684\u9700\u6c42\u5f00\u53d1\u591a\u529f\u80fd\u76ae\u80a4\u635f\u4f24\u4fee\u590d\u6750\u6599\u5bf9\u52a0\u901f\u4f24\u53e3\u6108\u5408\u5177\u6709\u91cd\u8981\u7684\u610f\u4e49\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u9488\u5bf9\u76ae\u80a4\u521b\u4f24\u5fae\u73af\u5883\uff0c\u897f\u5357\u4ea4\u901a\u5927\u5b66\u9c81\u96c4\u6559\u6388\u8bfe\u9898\u7ec4<\/strong>\u4ee5\u5177\u6709\u8fd1\u7ea2\u5916\u5149\u54cd\u5e94\u6027\u7684\u805a\u591a\u5df4\u80fa\u7eb3\u7c73\u9897\u7c92(PDA-NPs)\u3001\u751f\u7269\u76f8\u5bb9\u6027\u826f\u597d\u7684\u58f3\u805a\u7cd6(CS)\u548c\u4e1d\u7d20\u86cb\u767d(SF)\u4e3a\u539f\u6599\uff0c\u901a\u8fc7\u51b7\u51bb\u51dd\u80f6\u6280\u672f\u5236\u5907\u4e86\u517c\u5177\u8fd1\u7ea2\u5916\u5149\u70ed\u6cbb\u7597\u3001\u8c03\u63a7\u708e\u75c7\u53cd\u5e94\u3001\u6709\u6548\u6291\u5236\u7ec6\u83cc\u611f\u67d3\u7684\u4eff\u8d3b\u8d1d\u591a\u529f\u80fd\u590d\u5408\u51b7\u51bb\u51dd\u80f6\u6750\u6599\u3002\u8be5\u7814\u7a76\u6210\u679c\u4ee5\u9898\u4e3a\u201cMussel-inspired cryogels for promoting wound regeneration through photobiostimulation, modulating inflammatory response and suppressing bacterial invasion\u201d\u53d1\u8868\u5728Nanoscale<\/i><\/em>\u4e0a\uff08DOI: 10.1039\/C9NR03095F\uff09\u3002\u8be5\u8bba\u6587\u7531\u97e9\u7490\u535a\u58eb<\/b><\/strong>\u548c\u674e\u9e4f\u98de\u7855\u58eb<\/b><\/strong>\u5171\u540c\u5b8c\u6210\u3002\u897f\u5357\u4ea4\u901a\u5927\u5b66\u7684\u9c81\u96c4\u6559\u6388<\/b><\/strong>\u4e3a\u8be5\u8bba\u6587\u7684\u901a\u8baf\u4f5c\u8005\u3002\u8be5\u7814\u7a76\u5f97\u5230\u4e86\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u3001\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u7b49\u9879\u76ee\u7684\u652f\u6301\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe<\/b><\/strong>1<\/b><\/strong>\uff1a<\/b><\/strong>\u9488\u5bf9\u76ae\u80a4\u4f24\u53e3\u5fae\u73af\u5883<\/b><\/strong>\u7684\u4eff\u8d3b\u8d1d<\/b><\/strong>\u591a\u529f\u80fd<\/b><\/strong>PDA-NP<\/b><\/strong>s<\/b><\/strong>-CS\/SF<\/b><\/strong>\u590d\u5408\u51b7\u51bb\u51dd\u80f6\u7684<\/b><\/strong>\u8bbe\u8ba1\u601d\u8def<\/b><\/strong><\/p>\n

\"\"(a) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u5236\u5907\u3002<\/p>\n

(b) PDA-NPs-CS\/SF\u51bb\u80f6\u51dd\u80f6\u4f5c\u4e3a\u76ae\u80a4\u4f24\u53e3\u6577\u6599\u793a\u610f\u56fe\u3002<\/p>\n

(c) \u5728\u8fd1\u7ea2\u5916\u5149\u7167\u4e0b\uff0c\u56fa\u8f7dEGF\u7684PDA-NPs-CS\/SF\u51bb\u80f6\u51dd\u80f6\u901a\u8fc7\u5149\u751f\u7269\u523a\u6fc0\u3001\u8c03\u8282\u708e\u75c7\u53cd\u5e94\u548c\u6291\u5236\u7ec6\u83cc\u5165\u4fb5\u534f\u540c\u4f5c\u7528\u4ece\u800c\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\u7684\u793a\u610f\u56fe\u3002<\/p>\n

\u56fe2\uff1a\u51b7\u51bb\u51dd\u80f6\u7684\u5fae\u89c2\u5f62\u8c8c<\/b><\/strong>\u8868\u5f81<\/b><\/strong><\/p>\n

\"\"<\/p>\n

(a) CS\u51b7\u51bb\u51dd\u80f6\uff0c(b) SF\u51b7\u51bb\u51dd\u80f6\uff0c(c) PDA-NPs \uff0c(d) CS\/SF \u53ca(e) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684SEM\u5f62\u8c8c\u3002<\/p>\n

\u56fe<\/b><\/strong>3\uff1a\u51b7\u51bb\u51dd\u80f6\u7684<\/b><\/strong>\u529b\u5b66\u6027\u80fd\u8868\u5f81<\/b><\/strong><\/p>\n

\"\"<\/p>\n

(a) \u4e94\u74e3\u82b1\u5f62\u548c(b)\u5fc3\u5f62\u7684PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u53ef\u56de\u590d\u6027\u5c55\u793a\u3002<\/p>\n

(c) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u538b\u7f29-\u56de\u590d\u80fd\u529b\u3002<\/p>\n

(d) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u5faa\u73af\u538b\u7f29\u6027\u80fd\u3002<\/p>\n

(e) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u5178\u578b\u538b\u7f29\u66f2\u7ebf\u3002<\/p>\n

(f) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u538b\u7f29\u5f3a\u5ea6\u3002<\/p>\n

(g) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u5178\u578b\u62c9\u4f38\u66f2\u7ebf\u3002<\/p>\n

(h) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u6700\u5927\u62c9\u4f38\u5f3a\u5ea6\u3002<\/p>\n

(i) PDA-NPs-CS\/SF \u51b7\u51bb\u51dd\u80f6\u7684\u62c9\u4f38\u6bd4\u3002<\/p>\n

\u56fe4\uff1a\u51b7\u51bb\u51dd\u80f6\u7684\u5149\u70ed<\/b><\/strong>\u8f6c\u6362<\/b><\/strong>\u6027\u80fd\u548c\u5149\u70ed\u6297\u83cc\u6027\u80fd<\/b><\/strong><\/p>\n

\"\"<\/p>\n

(a,b) PDA-NPs-CS\/SF\u548cCS\/SF\u51b7\u51bb\u51dd\u80f6\u5728\u8fd1\u7ea2\u5916\u5149\u7167\u5c04\u4e0b\u7684\u6e29\u5ea6\u53d8\u5316\u56fe\u50cf\u548c\u66f2\u7ebf\u3002<\/p>\n

(c) PDA-NPs\u51b7\u51bb\u51dd\u80f6\u7684\u5149\u70ed\u7a33\u5b9a\u6027\u3002<\/p>\n

(d,e) PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u5728\u6709\u65e0\u8fd1\u7ea2\u5916\u5149\u7167\u5c04\u7684\u6297\u83cc\u6027\u3002<\/p>\n

\u56fe5\uff1a\u901a\u8fc7\u514d\u75ab\u8367\u5149\u67d3\u8272\u5206\u6790PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u7684\u4f53\u5916ROS\u6e05\u9664\u80fd\u529b<\/b><\/strong><\/p>\n

\"\"<\/p>\n

(a)\u00a0<\/b><\/strong>DPPH\u5206\u522b\u4e0e\u00a0CS\/SF\u51b7\u51bb\u51dd\u80f6\uff0cPDA-NPs\uff0cPDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u540e\u7684UV-Vis\u5149\u8c31\u3002<\/p>\n

(b) \u4e0d\u540cPDA-NPs\u542b\u91cf\u7684PDA-NPs-CS\/SF\u51b7\u51bb\u51dd\u80f6\u6e05\u9664DPPH\u7684\u80fd\u529b\u3002<\/p>\n

(c) CS\/SF\u548cPDA-NPS-CS\/SF\u51b7\u51bb\u51dd\u80f6\u4e0eH2<\/sub>O2<\/sub>\u523a\u6fc0\u7684\u5de8\u566c\u7ec6\u80de\u5171\u57f9\u517b\u540e\u8367\u5149\u56fe\u50cf\u3002<\/p>\n

(d,e) \u6d41\u5f0f\u7ec6\u80de\u4eea\u68c0\u6d4b\u4e0d\u540c\u5904\u7406\u7ec4\u4e2dRAW264.7\u7ec6\u80de\u5185\u7684ROS\u8868\u8fbe\u6c34\u5e73\u3002<\/p>\n

\u56fe<\/b><\/strong>6<\/b><\/strong>\uff1a\u51b7\u51bb\u51dd\u80f6\u534f\u540c<\/b><\/strong>\u8fd1\u7ea2\u5916\u5149<\/b><\/strong>\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408<\/b><\/strong><\/p>\n

\"\"<\/p>\n

(a) \u8fd1\u7ea2\u5916\u5149\u8f90\u5c04SD\u5927\u9f20\u76ae\u80a4\u7f3a\u635f\u90e8\u4f4d\u7684\u7167\u7247\u3002<\/p>\n

(b)\u00a0\u5728\u7ea2\u5916\u5149\u8f90\u5c04\u4e0b\uff0c\u51b7\u51bb\u51dd\u80f6\u5728\u690d\u5165\u4f24\u53e3\u7684\u70ed\u6210\u50cf\u7167\u7247\u3002<\/p>\n

(c) \u65e0\u8fd1\u7ea2\u5916\u5149\u7167\u60c5\u51b5\u4e0b\uff0c\u4e0d\u540c\u5904\u7406\u7ec4\u7684\u4e2dSD\u5927\u9f20\u76ae\u80a4\u6108\u5408\u60c5\u51b5\u3002<\/p>\n

(d) \u5728\u8fd1\u7ea2\u5916\u5149\u4e0b\uff0c\u4e0d\u540c\u5904\u7406\u7ec4\u7684\u4e2dSD\u5927\u9f20\u76ae\u80a4\u6108\u5408\u60c5\u51b5\u3002<\/p>\n

(e) \u4f24\u53e3\u6108\u5408\u7387\u3002<\/p>\n

(f) \u690d\u516521\u5929\u540e\u4f24\u53e3\u7ec4\u7ec7\u7684H&E\u67d3\u8272\u3002<\/p>\n

\u3010\u5c0f\u7ed3<\/strong>\u3011<\/b><\/p>\n

\u672c\u7814\u7a76\u5236\u5907\u4e86\u8fd1\u7ea2\u5916\u5149\u70ed\u54cd\u5e94\u6027\u7684PDA-NPs-CS\/SF \u51b7\u51bb\u51dd\u80f6\uff0c\u5177\u6709\u8c03\u63a7\u708e\u75c7\u53cd\u5e94\u548c\u62b5\u5236\u7ec6\u83cc\u5165\u4fb5\u3001\u4fc3\u8fdb\u7ec4\u7ec7\u518d\u751f\u7684\u591a\u91cd\u529f\u80fd\u3002\u8be5\u51b7\u51bb\u51dd\u80f6\u5177\u6709\u4eff\u751f\u7ec6\u80de\u5916\u57fa\u8d28\u5fae\u73af\u5883\u7684\u591a\u5b54\u7ed3\u6784\uff0cPDA-NPs\u7684\u5f15\u5165\u4fc3\u8fdb\u4e86\u6210\u7ea4\u7ef4\u7ec6\u80de\u5728\u51b7\u51bb\u51dd\u80f6\u8868\u9762\u7c98\u9644\u548c\u589e\u6b96\uff0c\u6709\u5229\u4e8e\u7ec4\u7ec7\u957f\u5165\u3002\u5176\u6b21\uff0cPDA-NPs\u5177\u6709\u6e05\u9664\u81ea\u7531\u57fa\u7684\u80fd\u529b\uff0c\u4f7f\u51b7\u51bb\u51dd\u80f6\u80fd\u6709\u6548\u6d88\u9664\u4f24\u53e3\u708e\u75c7\u53cd\u5e94\u9636\u6bb5\u4ea7\u751f\u7684\u6d3b\u6027\u6c27\uff0c\u4ece\u800c\u907f\u514d\u6c27\u5316\u5e94\u6fc0\u5bfc\u81f4\u4f24\u7684\u53e3\u957f\u671f\u4e0d\u80fd\u6108\u5408\u3002\u518d\u6b21\uff0cPDA-NPs\u5177\u6709\u826f\u597d\u7684\u5149\u70ed\u8f6c\u6362\u6027\u80fd\uff0c\u8d4b\u4e88\u8be5\u51b7\u51bb\u51dd\u80f6\u5728\u4f4e\u529f\u7387\u8fd1\u7ea2\u5916\u5149\u7167\u5c04\u4e0b\u5373\u53ef\u8fc5\u901f\u5347\u6e29\u7684\u7279\u6027\uff0c\u4ece\u800c\u8868\u73b0\u51fa\u826f\u597d\u7684\u8fd1\u7ea2\u5916\u5149\u70ed\u6297\u83cc\u6548\u679c\uff0c\u6291\u5236\u4f24\u53e3\u6108\u5408\u671f\u95f4\u7684\u7ec6\u83cc\u5165\u4fb5\u5bfc\u81f4\u7684\u611f\u67d3\u3002\u6700\u540e\uff0cPDA-NPs\u9ad8\u5316\u5b66\u6d3b\u6027\uff0c\u80fd\u591f\u56fa\u8f7d\u5177\u6709\u8bf1\u5bfc\u76ae\u80a4\u7ec4\u7ec7\u518d\u751f\u529f\u80fd\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\uff0c\u4fc3\u8fdb\u7ec6\u80de\u6d3b\u6027\u548c\u7ec4\u7ec7\u518d\u751f\u3002\u603b\u4e4b\uff0c\u9488\u5bf9\u76ae\u80a4\u521b\u4f24\u5fae\u73af\u5883\u8bbe\u8ba1\u7684\u4eff\u8d3b\u8d1d\u591a\u529f\u80fd\u590d\u5408\u51b7\u51bb\u51dd\u80f6\u6750\u6599\uff0c\u4e0e\u80fd\u591f\u5b9e\u73b0\u751f\u7269\u5316\u5b66\u5149\u70ed\u534f\u540c\u4f5c\u7528\uff0c\u52a0\u901f\u76ae\u80a4\u5168\u5c42\u521b\u9762\u6108\u5408\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/b><\/strong><\/p>\n

Mussel-inspired cryogels for promoting wound regeneration through photobiostimulation, modulating inflammatory response and suppressing bacterial invasion<\/u><\/a>\u00a0(Nanoscale, 2019)<\/p>\n

\u672c\u6587\u7531\u897f\u5357\u4ea4\u901a\u5927\u5b66\u9c81\u96c4\u6559\u6388\u8bfe\u9898\u7ec4\u4f9b\u7a3f\u3002<\/p>\n

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