{"id":181205,"date":"2019-07-22T18:38:17","date_gmt":"2019-07-22T10:38:17","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=181205"},"modified":"2019-07-22T20:43:11","modified_gmt":"2019-07-22T12:43:11","slug":"%e6%a0%a1%e7%a8%bf%e6%9c%aa%e5%9b%9e%e5%a4%8d-%e4%b8%ad%e7%a7%91%e9%99%a2%e7%94%9f%e7%89%a9%e7%89%a9%e7%90%86%e6%89%80acc-chem-res%e7%bb%bc%e8%bf%b0%ef%bc%9a%e6%96%b0%e4%b8%80%e4%bb%a3%e4%ba%ba","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=181205","title":{"rendered":"\u4e2d\u79d1\u9662\u751f\u7269\u7269\u7406\u6240Acc. Chem. Res\u7efc\u8ff0\uff1a\u65b0\u4e00\u4ee3\u4eba\u5de5\u9176\u2014\u2014\u7eb3\u7c73\u9176\u7684\u65b0\u6982\u5ff5\u53ca\u5e94\u7528"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u00a0\u00a0\u5929\u7136\u9176\uff0c\u5177\u6709\u50ac\u5316\u6d3b\u6027\u9ad8\u3001\u5e95\u7269\u4e13\u4e00\u6027\u3001\u50ac\u5316\u591a\u6837\u6027\u3001\u53cd\u5e94\u6e29\u548c\u4ee5\u53ca\u6d3b\u6027\u53ef\u8c03\u8282\u7b49\u7279\u70b9\uff0c\u5728\u73af\u5883\u4fdd\u62a4\u4ee5\u53ca\u75be\u75c5\u8bca\u65ad\u4e0e\u6cbb\u7597\u7b49\u9886\u57df\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u4f46\u662f\u7531\u4e8e\u5929\u7136\u9176\u81ea\u8eab\u7684\u5c40\u9650\u6027\u5982\u4f4e\u7a33\u5b9a\u6027\uff0c\u9ad8\u6210\u672c\u4ee5\u53ca\u96be\u5b58\u50a8\u96be\u4ee5\u771f\u6b63\u5e94\u7528\u3002\u4e3a\u4e86\u89e3\u51b3\u5929\u7136\u9176\u5728\u5e94\u7528\u65b9\u9762\u7684\u5c40\u9650\u6027\uff0c\u4eba\u4eec\u4e00\u76f4\u81f4\u529b\u4e8e\u53d1\u5c55\u4eba\u9020\u9176\u4f5c\u4e3a\u5929\u7136\u9176\u7684\u66ff\u4ee3\u54c1\u3002\u8fd1\u5e74\u6765\uff0c\u4eba\u4eec\u53d1\u73b0\u67d0\u4e9b\u7eb3\u7c73\u6750\u6599\u540c\u6837\u5177\u6709\u6a21\u62df\u5929\u7136\u9176\u50ac\u5316\u6d3b\u6027\u7684\u80fd\u529b\u3002\u4e0e\u4f20\u7edf\u7684\u4eba\u5de5\u6a21\u62df\u9176\u76f8\u6bd4\uff0c\u8fd9\u7c7b\u65b0\u578b\u7684\u7eb3\u7c73\u9176\u9664\u4e86\u540c\u6837\u5177\u6709\u66f4\u52a0\u7a33\u5b9a\u7684\u5316\u5b66\u6027\u8d28\u548c\u50ac\u5316\u6d3b\u6027\u3001\u6210\u672c\u4f4e\u7b49\u4f18\u52bf\uff0c\u66f4\u6709\u7740\u81ea\u8eab\u72ec\u7279\u7684\u6027\u8d28\uff0c\u4f8b\u5982\u66f4\u6613\u5927\u89c4\u6a21\u5236\u5907\u3001\u6bd4\u8868\u9762\u79ef\u9ad8\u3001\u50ac\u5316\u6d3b\u6027\u53ef\u8c03\u63a7\u7b49\u3002\u56e0\u6b64\uff0c\u8fd1\u51e0\u5e74\u6765\uff0c\u7eb3\u7c73\u9176\u5728\u751f\u7269\u3001\u533b\u5b66\u3001\u519c\u4e1a\u3001\u73af\u5883\u6cbb\u7406\u3001\u56fd\u9632\u5b89\u5168\u7b49\u591a\u4e2a\u9886\u57df\u8d8a\u6765\u8d8a\u53d7\u5230\u4eba\u4eec\u7684\u5173\u6ce8\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u4e2d\u79d1\u9662\u751f\u7269\u7269\u7406\u6240\u7814\u7a76\u5458\u960e\u9521\u8574\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u5728Accounts of <\/em>Chemical <\/em>Research<\/em><\/strong>\u4e0a\u53d1\u8868\u4e86\u9898\u4e3a\u201c<\/strong>Nanozymes: From New Concepts, Mechanisms, and Standards to Applications<\/strong>\u201d<\/strong>\u7684\u7efc\u8ff0\u3002\u8fd9\u7bc7\u7efc\u8ff0\u8986\u76d6\u4e86\u5404\u79cd\u7c7b\u578b\u7684\u7eb3\u7c73\u9176\u53ca\u5176\u5728\u751f\u7269\u4f20\u611f\u3001\u75be\u75c5\u8bca\u7597\u4ee5\u53ca\u73af\u5883\u68c0\u6d4b\u4e2d\u7684\u5e94\u7528\u3002\u540c\u65f6\u8be5\u7efc\u8ff0\u57fa\u4e8e\u76ee\u524d\u7684\u7eb3\u7c73\u9176\u7406\u8bba\u57fa\u7840\uff0c\u8bc4\u4ef7\u7eb3\u7c73\u9176\u6027\u80fd\u7684\u6807\u51c6\u5e76\u5bf9\u52a8\u529b\u5b66\u8fdb\u884c\u7814\u7a76\uff0c\u540c\u65f6\u5bf9\u7eb3\u7c73\u9176\u672a\u6765\u524d\u666f\u8fdb\u884c\u8ba8\u8bba\u3002<\/p>\n

\u00a0<\/strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u00a0\u56fe1 \u57fa\u4e8eFe3<\/sub>O4<\/sub>\u7684\u7c7b\u8fc7\u6c27\u5316\u9176\u7eb3\u7c73\u9176<\/strong><\/p>\n

\"\"(a)\u4e0d\u540c\u5927\u5c0f\u7684Fe3<\/sub>O4<\/sub> NPs\u7684TEM\u56fe\uff1b<\/p>\n

(b) Fe3<\/sub>O4<\/sub> NPs\u5728H2<\/sub>O2<\/sub>\u5b58\u5728\u4e0b\u50ac\u5316\u5404\u79cd\u8fc7\u6c27\u5316\u7269\u9176\u5e95\u7269\uff08TMB\uff0cDAB\u548cOPD\uff09\uff0c\u4ea7\u751f\u4e0d\u540c\u7684\u989c\u8272\u53cd\u5e94\uff1b<\/p>\n

(c) Fe3<\/sub>O4<\/sub> NPs\u50ac\u5316\u673a\u7406\u3002AH\u4ee3\u8868\u8fc7\u6c27\u5316\u7269\u9176\u5e95\u7269\uff0c\u5b83\u662f\u6c22\u4f9b\u4f53\uff1b<\/p>\n

\u56fe<\/strong>2 <\/strong>\u57fa\u4e8e\u6c2e\u63ba\u6742\u78b3\u7eb3\u7c73\u7c92\u5b50\u7684\u7eb3\u7c73\u9176<\/strong><\/p>\n

\"\"<\/p>\n

(a) \u6c2e\u63ba\u6742\u7684\u78b3\u7eb3\u7c73\u9897\u7c92\uff08N-PCNS\uff09TEM\u56fe\uff1b<\/p>\n

(b) N-PCNSs\u7684\u50ac\u5316\u673a\u7406\uff1b<\/p>\n

(c)\u57fa\u4e8eN-PCNSs\u7684\u7c7b\u6c27\u5316\u9176\uff0c\u8fc7\u6c27\u5316\u7269\u9176\uff0c\u8fc7\u6c27\u5316\u6c22\u9176\u548c\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9176\u52a8\u529b\u5b66\u7814\u7a76\uff1b<\/p>\n

\u56fe<\/strong>3 <\/strong>\u7528\u4e8e\u514d\u75ab\u6d4b\u5b9a\u7684<\/strong>Fe3<\/sub>O4<\/sub><\/strong>\u7eb3\u7c73\u7c92\u5b50\u7eb3\u7c73\u9176<\/strong><\/p>\n

\"\"(a) ELISA\u514d\u75ab\u68c0\u6d4b\u6a21\u5f0f\uff1b<\/p>\n

(b)\u5939\u5fc3\u6355\u83b7\u514d\u75ab\u5206\u6790\u68c0\u6d4b\u6a21\u5f0f\uff1b<\/p>\n

(c)\u6761\u5e26\u514d\u75ab\u68c0\u6d4b\u6a21\u5f0f\uff1b<\/p>\n

\u56fe<\/strong>4 <\/strong>\u80bf\u7624\u7ec4\u7ec7\u7684<\/strong>M-HFn<\/strong>\u67d3\u8272<\/strong><\/p>\n

\"\"<\/p>\n

(a) M-HFn NPs\u7684\u5236\u5907\uff1b<\/p>\n

(b) \u80bf\u7624\u7ec4\u7ec7\u7684M-HFn NPs\u67d3\u8272\uff1b\uff08\u77f3\u8721\u5305\u57cb\u7684\u4e34\u5e8a\u80bf\u7624\u7ec4\u7ec7\u53ca\u5176\u76f8\u5e94\u7684\u6b63\u5e38\u548c\u635f\u4f24\u7ec4\u7ec7\u7528FITC\u7f00\u5408\u7684HFn\u86cb\u767d\u58f3\u548cM-HFn NP\u67d3\u8272\u3002\u80bf\u7624\u7ec4\u7ec7\u663e\u793aM-HFn NPs\uff08\u68d5\u8272\uff09\u548cFITC-\u7f00\u5408\u7684HFn\u86cb\u767d\u58f3\uff08\u7eff\u8272\u8367\u5149\uff09\u7684\u5f3a\u9633\u6027\u67d3\u8272\uff0c\u800c\u6b63\u5e38\u548c\u635f\u4f24\u7ec4\u7ec7\u5bf9\u7167\u5bf9M-HFn NP\u548cFITC\u7f00\u5408\u7684HFn\u662f\u9634\u6027\u7684\uff09<\/p>\n

\u4f20\u7edf\u514d\u75ab\u7ec4\u5316\u4e0e<\/strong>M-HFn<\/strong>\u7eb3\u7c73\u9176\u67d3\u8272\u80bf\u7624\u7ec4\u7ec7\u7684\u6bd4\u8f83<\/strong><\/p>\n

\"\"<\/p>\n

\u4f20\u7edf\u514d\u75ab\u7ec4\u5316\u4e0eM-HFn\u7eb3\u7c73\u9176\u67d3\u8272\u80bf\u7624\u7ec4\u7ec7\u7684\u6bd4\u8f83<\/p>\n

\u56fe<\/strong>6<\/strong>\u7528\u4e8e\u4e0d\u7a33\u5b9a\u52a8\u8109\u7ca5\u6837\u786c\u5316\u6591\u5757\u75c5\u7406\u5b66\u9274\u5b9a\u7684<\/strong>M-HFn<\/strong>\u7eb3\u7c73\u9176<\/strong><\/p>\n

\u00a0\"\"<\/strong>(a) M-HFn NPs\u7684\u5236\u5907\u8fc7\u7a0b\u793a\u610f\u56fe\uff1b<\/p>\n

(b) HFn\u7eb3\u7c73\u7b3c\uff08\u5de6\uff09\u548cM-HFn NP\uff08\u53f3\uff09\u7684Cryo-EM\u56fe\u50cf\uff1b<\/p>\n

(c) M-HFn\u7eb3\u7c73\u9176\u7279\u5f02\u6027\u67d3\u8272\uff1b<\/p>\n

\u56fe<\/strong>7 <\/strong>\u7eb3\u7c73\u9176\u56ca\u6ce1\u7528\u4e8e\u80bf\u7624<\/strong>H2<\/sub>O2<\/sub><\/strong>\u54cd\u5e94\u6027\u50ac\u5316\u5149\u58f0\u6210\u50cf\u793a\u610f\u56fe<\/strong><\/p>\n

\"\"<\/p>\n

\u00a0<\/strong>\u56fe<\/strong>8<\/strong>\u6807\u51c6\u5316\u7c7b\u8fc7\u6c27\u5316\u7269\u7eb3\u7c73\u9176\u50ac\u5316\u6d3b\u6027<\/strong><\/p>\n

\"\"<\/p>\n

(a) \u4e09\u79cd\u5178\u578b\u7684\u8fc7\u6c27\u5316\u7269\u7eb3\u7c73\u9176\uff08Fe3<\/sub>O4<\/sub>\uff0c\u78b3\u548cAu NP\uff09\u7684TEM\u56fe\uff1b<\/p>\n

(b) Fe3<\/sub>O4<\/sub>\uff0c\u78b3\u548cAu NPs\u50ac\u5316\u8fc7\u6c27\u5316\u7269\u9176\u5e95\u7269\uff1b<\/p>\n

(c) \u7531Fe3<\/sub>O4<\/sub>\uff08\u7ea2\u8272\uff09\uff0c\u78b3\uff08\u9ed1\u8272\uff09\u548cAu\uff08\u84dd\u8272\uff09\u7eb3\u7c73\u9176\u50ac\u5316TMB\u53cd\u5e94\u7684\u53cd\u5e94\u65f6\u95f4\u66f2\u7ebf\uff1b<\/p>\n

(d) Fe3<\/sub>O4<\/sub>\uff0c\u78b3\u548cAu\u7eb3\u7c73\u9176\u7684\u6bd4\u6d3b\u6027\uff08U \/ mg\uff09\uff1b<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u00a0\u00a0\u4f5c\u8005\u5728\u672c\u7efc\u8ff0\u4e2d\u5168\u9762\u4ecb\u7ecd\u4e86\u5404\u79cd\u7c7b\u578b\u7684\u7eb3\u7c73\u9176\u53ca\u5176\u5728\u751f\u7269\u4f20\u611f\u3001\u75be\u75c5\u8bca\u7597\u4ee5\u53ca\u73af\u5883\u68c0\u6d4b\u4e2d\u7684\u5e94\u7528\u3002\u540c\u65f6\u8be5\u7efc\u8ff0\u57fa\u4e8e\u76ee\u524d\u7684\u7eb3\u7c73\u9176\u7406\u8bba\u57fa\u7840\uff0c\u91cd\u65b0\u5b9a\u4e49\u5e76\u4e14\u8bc4\u4ef7\u7eb3\u7c73\u9176\u6027\u80fd\u7684\u6807\u51c6\u5e76\u4e14\u7814\u7a76\u76f8\u5173\u52a8\u529b\u5b66\uff0c\u5e76\u57fa\u4e8e\u6b64\u5bf9\u7eb3\u7c73\u9176\u672a\u6765\u524d\u666f\u8fdb\u884c\u8ba8\u8bba\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Nanozymes: From New Concepts, Mechanisms, and Standards to Applications<\/a><\/p>\n

\u539f\u6587\u94fe\u63a5\uff1ahttps:\/\/pubs.acs.org\/doi\/10.1021\/acs.accounts.9b00140<\/a> (Acc. Chem. Res. 2019, DOI: 10.1021\/acs.accounts.9b00140),<\/p>\n

\u672c\u6587\u7531LUMO\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u5ba1\u6838\u6574\u7406\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n

\u6295\u7a3f\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaorenkefu\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u00a0\u00a0\u5929\u7136\u9176\uff0c\u5177\u6709\u50ac\u5316\u6d3b\u6027\u9ad8\u3001\u5e95\u7269\u4e13\u4e00\u6027\u3001\u50ac\u5316\u591a\u6837\u6027\u3001\u53cd\u5e94\u6e29\u548c\u4ee5\u53ca\u6d3b\u6027\u53ef\u8c03\u8282\u7b49\u7279\u70b9\uff0c\u5728\u73af\u5883\u4fdd\u62a4\u4ee5\u53ca\u75be\u75c5\u8bca\u65ad\u4e0e\u6cbb\u7597\u7b49\u9886\u57df\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u4f46\u662f\u7531\u4e8e\u5929\u7136\u9176\u81ea\u8eab\u7684…<\/p>\n","protected":false},"author":802,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[],"class_list":["post-181205","post","type-post","status-publish","format-standard","hentry","category-jiedu"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/181205"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/802"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=181205"}],"version-history":[{"count":5,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/181205\/revisions"}],"predecessor-version":[{"id":181283,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/181205\/revisions\/181283"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=181205"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=181205"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=181205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}