{"id":181437,"date":"2019-07-30T06:30:00","date_gmt":"2019-07-29T22:30:00","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=181437"},"modified":"2019-07-29T21:10:15","modified_gmt":"2019-07-29T13:10:15","slug":"nature%ef%bc%9a%e5%a4%a7%e6%95%b0%e6%8d%ae%e4%b8%8b%ef%bc%8c%e4%b8%8d%e5%af%b9%e7%a7%b0%e5%82%ac%e5%8c%96%e4%b8%ad%e5%af%b9%e6%98%a0%e9%80%89%e6%8b%a9%e6%80%a7%e7%9a%84%e9%a2%84%e6%b5%8b","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=181437","title":{"rendered":"Nature\uff1a\u5927\u6570\u636e\u4e0b\uff0c\u4e0d\u5bf9\u79f0\u50ac\u5316\u4e2d\u5bf9\u6620\u9009\u62e9\u6027\u7684\u9884\u6d4b"},"content":{"rendered":"

\u4f5c\u8005\u4ecb\u7ecd\uff1a<\/strong><\/p>\n

Matthew S. Sigman\u662f\u7f8e\u56fd\u6709\u673a\u5316\u5b66\u5bb6\uff0c\u5e08\u627fE. N. Jacobsen\uff0c\u73b0\u4e3a\u72b9\u4ed6\u5927\u5b66\u6559\u6388\u3002<\/p>\n

\u7ecf\u5386\uff1a<\/strong><\/p>\n

1992\u7d22\u8bfa\u9a6c\u5dde\u7acb\u5927\u5b66\uff08California\uff09B. S.\uff08Michael E. Wright\u6559\u6388\uff09\uff0c1996 \u534e\u76db\u987f\u5dde\u7acb\u5927\u5b66 Ph. D\uff08Bruce E. Eaton\u6559\u6388\uff09\uff0c1996-1999 \u54c8\u4f5b\u5927\u5b66 \u535a\u58eb\u7814\u7a76\u5458 (E. N. Jacobsen\u6559\u6388)\uff0c1999-2004 \u72b9\u4ed6\u5927\u5b66 \u52a9\u6559\uff0c2004-2008 \u72b9\u4ed6\u5927\u5b66 \u526f\u6559\u6388\uff0c2008-\u73b0\u5728\u72b9\u4ed6\u5927\u5b66 \u6559\u6388\uff0c2009-2010 \u72b9\u4ed6\u5927\u5b66 Huntsman Cancer Institute \u5ba2\u5ea7\u6559\u6388\u3002<\/p>\n

\"\"<\/p>\n

\u7814\u7a76\u6982\u8981\uff1a<\/strong><\/p>\n

1. Pd\u50ac\u5316\u70ef\u70c3\u4e0d\u5bf9\u79f0\u5b98\u80fd\u56e2\u5316[1]<\/sup><\/p>\n

2. \u591a\u7ef4\u6a21\u62df\u4f18\u5316\u5bf9\u6620\u9009\u62e9\u6027\u7684\u50ac\u5316\u5242\u548c\u914d\u4f53\u8bbe\u8ba1\uff08\u7269\u7406\u6709\u673a\u5316\u5b66\uff09[2]<\/sup><\/p>\n

3. \u7535\u50ac\u5316\u4e0e\u6c27\u5316\u8fd8\u539f\u6db2\u6d41\u7535\u6c60\uff08Redox Flow Batteries\uff09[3]<\/sup><\/p>\n

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\"\"<\/p>\n

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\u7136\u540e\u5c06\u7ebf\u6027\u56de\u5f52\u7b97\u6cd5\u5e94\u7528\u4e8e\u6574\u4e2a\u6570\u636e\u96c6\uff08367\u4e2a\u53cd\u5e94\uff09\uff0c\u4ee5\u786e\u5b9a\u7531\u5de5\u4f5c\u6d41\u7a0b\u7684\u524d\u4e00\u6b65\u9aa4\u4e2d\u6536\u96c6\u7684\u53c2\u6570\u5b9a\u4e49\u7684\u6bcf\u4e2a\u53cd\u5e94\u53d8\u91cf\u7684\u5206\u5b50\u7ed3\u6784\u4e0e\u5b9e\u9a8c\u786e\u5b9a\u7684\u5bf9\u6620\u9009\u62e9\u6027\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u3002<\/p>\n

\u56fe 2.\u00a0\u7efc\u5408\u6a21\u578b\u5f00\u53d1<\/p>\n

\"\"a. \u00a0\u901a\u8fc7\u6bcf\u4e2a\u53cd\u5e94\u53d8\u91cf\u7684\u53c2\u6570\u5316\u4fc3\u8fdb\u5305\u542b367\u4e2a\u6570\u636e\u6761\u76ee\u7684\u7efc\u5408\u56de\u5f52\u6a21\u578b\u3002’sol’\u662f\u6eb6\u5242\uff0c’NBON’\u548c’NBOC’\u662f\u4e9a\u80fa\u5929\u7136\u952e\u8f68\u9053\u53c2\u6570\uff0cLs\u662f\u6700\u5c0f\u4e9a\u80fa\u53d6\u4ee3\u57fa\u7684\u7acb\u4f53\u63cf\u8ff0\u7b26\uff0c’H-X-CNu’\u662f\u4eb2\u6838\u89d2\u5ea6\u6d4b\u91cf\uff0cLcat\u662f\u50ac\u5316\u52422-\u53d6\u4ee3\u57fa\u7684\u957f\u5ea6\u3002\u6b63\u7535\u6027\u767e\u5206\u6bd4\u5bf9\u6620\u4f53\u8fc7\u91cf\uff08\uff05e\u3002\uff09\u503c\u8868\u793aE-\u4e9a\u80fa\u8fc7\u6e21\u6001\uff0c\u8d1f\u7535\u6027\u767e\u5206\u6bd4\u5bf9\u6620\u4f53\u8fc7\u91cf\u503c\u8868\u793aZ-\u4e9a\u80fa\u8fc7\u6e21\u6001\u3002 \u8be5\u7ebf\u662f\u62df\u5408\u7684\uff0cy = 0.88x + 0.05\u3002 \u7559\u4e00\u6cd5\uff08LOO\uff09\u4ea4\u53c9\u9a8c\u8bc1\u5f97\u5206\u4e3a0.87; \u5e73\u5747k\u500d\uff08\u6b64\u5904\u4e3a4\u500d\uff09\u4ea4\u53c9\u9a8c\u8bc1\u5f97\u5206\u4e3a0.87; \u9002\u5408\u5ea6R2\u7684\u4f18\u52a3\u4e3a0.88; \u9884\u6d4b\u7684R2\u4e3a0.87\u3002<\/p>\n

b. \u00a0\u901a\u8fc7\u7559\u4e00\u53cd\u5e94\uff08LORO\uff09\u5206\u6790\u6d4b\u8bd5\u6570\u636e\u96c6\u4e2d\u7684\u673a\u7406\u53ef\u8f6c\u79fb\u6027\u3002 \u4e0d\u540c\u7684\u53cd\u5e94\uff08\u7531\u5404\u4e2a\u51fa\u7248\u7269\u786e\u5b9a\uff09\u88ab\u5b9a\u4e49\u4e3a\u9a8c\u8bc1\u96c6\u3002\u8be5\u7ebf\u662f\u62df\u5408\u7684\uff0cy = 0.84x + 0.12\u3002R2\u662f84; \u4f7f\u7528LORO\u9884\u6d4b\u7684R2\uff08\u8fd9\u91cc\u7701\u7565\u4e86\u4e03\u4e2a\u53cd\u5e94\uff09\u662f0.85\u3002<\/p>\n

\u8026\u5408\u5230\u6a21\u578b\u548c\u9a8c\u8bc1\u7b56\u7565\u7684\u63cf\u8ff0\u7b26\u5b9a\u4e49\u786e\u5b9e\u8bc1\u660e\u4e86\u6a21\u5f0f\u53ef\u4ee5\u5339\u914d\u3002\u8fd9\u4e0e\u4e00\u7ec4\u786e\u5b9a\u7684\u5173\u952e\u975e\u5171\u4ef7\u76f8\u4e92\u4f5c\u7528\u5728\u4e00\u822c\u53cd\u5e94\u7c7b\u578b\u4e2d\u8d4b\u4e88\u4e0d\u5bf9\u79f0\u8bf1\u5bfc\u7684\u5047\u8bbe\u662f\u4e00\u81f4\u7684\u3002\u4ece\u672c\u8d28\u4e0a\u8bb2\uff0c\u8fd9\u4e2a\u5de5\u4f5c\u6d41\u7a0b\u63d0\u4f9b\u7684\u8bc1\u636e\u8868\u660e\uff0c\u4e00\u79cd\u53cd\u5e94\u53ef\u7528\u4e8e\u5b9a\u91cf\u5730\u9884\u6d4b\u53e6\u4e00\u79cd\u53cd\u5e94\u7684\u7ed3\u679c\u3002<\/p>\n

\u8d8b\u52bf\u5206\u6790<\/b><\/strong><\/p>\n

\u867d\u7136\u56fe2\u4e2d\u7684\u7efc\u5408\u6a21\u578b\u5c55\u73b0\u4e86\u6240\u9009\u53c2\u6570\u6765\u63cf\u8ff0\u8be5\u7cfb\u7edf\u7684\u4e00\u822c\u6027\u7684\u80fd\u529b\uff0c\u4f46\u6211\u4eec\u5de5\u4f5c\u6d41\u7a0b\u7684\u6700\u7ec8\u76ee\u6807\u662f\u8bc6\u522b\u5fae\u5999\u7684\u6f5c\u5728\u673a\u5236\u73b0\u8c61\u3002<\/p>\n

\u56fe 3. \u91cd\u70b9\u5173\u8054\u6027\u7684\u5f00\u53d1<\/p>\n

\"\"a. \u00a0\u56de\u5f52E-imine\u6a21\u578b\u5305\u542b\u6765\u81ea9\u4e2a\u6587\u732e\u8d44\u6599\u7684\u6570\u636e\u6316\u6398\u7684204\u4e2a\u6761\u76ee\u3002 ‘CI’\u548c’PEOE5’\u662f\u6eb6\u5242\u63cf\u8ff0\u7b26\uff0c’B5PG’\u548cLl\u662f\u4e9a\u80fa\u7a7a\u95f4\u63cf\u8ff0\u7b26\uff0cLUMO\u662f\u63cf\u8ff0\u4eb2\u6838\u8bd5\u5242\u7684\u6700\u4f4e\u672a\u5360\u5206\u5b50\u8f68\u9053\u80fd\u91cf\uff0cLcat\u662f\u50ac\u5316\u52422-\u53d6\u4ee3\u57fa\u7684\u957f\u5ea6\uff0c’iPOas’\u662f P-O\u4e0d\u5bf9\u79f0\u62c9\u4f38\u5f3a\u5ea6\u548c’AREA’\u662f\u4e00\u4e2a\u504f\u8fdc\u7684\u73af\u5883\u89d2\u5ea6\u3002\u8be5\u7ebf\u662f\u62df\u5408\u7684\uff0cy = 0.80x + 0.35\u3002LOO\u4ea4\u53c9\u9a8c\u8bc1\u5f97\u5206\u4e3a76; \u5e73\u5747k\u500d\uff08\u6b64\u5904\u4e3a4\u500d\uff09\u4ea4\u53c9\u9a8c\u8bc1\u5f97\u5206\u4e3a0.74; R2\u662f0.80; \u9884\u6d4b\u7684R2\u4e3a0.73\u3002<\/p>\n

b. \u00a0\u89e3\u8bfbE-imine\u6a21\u578b\u672f\u8bed\u3002\u8be5\u6a21\u578b\u5f3a\u8c03\u4e86\u7a7a\u95f4\u548c\u7535\u5b50\u56e0\u7d20\u7684\u91cd\u8981\u6027\u3002\u5408\u7406\u7684\u5927\u50ac\u5316\u5242\u548c\u4e9a\u80fa\u53d6\u4ee3\u57fa\u5bfc\u81f4\u9ad8\u6c34\u5e73\u7684\u5bf9\u6620\u9009\u62e9\u6027; \u5982\u679c\u8fd9\u4e24\u4e2a\u7ec4\u5206\u5339\u914d\uff0c\u4efb\u4f55\u4eb2\u6838\u8bd5\u5242\u5e94\u8be5\u662f\u76f8\u5bb9\u7684\u3002<\/p>\n

c. \u00a0\u56de\u5f52Z-\u4e9a\u80fa\u6a21\u578b\u5305\u542b\u6765\u81ea\u516b\u4e2a\u6587\u732e\u8d44\u6599\u7684\u6570\u636e\u6316\u6398\u7684147\u4e2a\u6761\u76ee\u3002’NBOH’\u548c’NBOPG’\u662f\u4e9a\u80fa\u5929\u7136\u952e\u8f68\u9053\u53c2\u6570; Ls\u662f\u6700\u5c0f\u4e9a\u80fa\u53d6\u4ee3\u57fa\u7684\u7acb\u4f53\u63cf\u8ff0\u7b26; ‘B5Nu’\u662f\u4eb2\u6838\u4f53\u7a7a\u95f4\u63cf\u8ff0\u7b26\uff0c’B1cat’\u662fSterimol B1\u672f\u8bed\u3002 \u8be5\u7ebf\u662f\u62df\u5408\u7684\uff0cy = 0.83x – 0.24\u3002LOO\u4ea4\u53c9\u9a8c\u8bc1\u5f97\u5206\u4e3a80; \u5e73\u5747k\u500d\uff08\u6b64\u5904\u4e3a4\u500d\uff09\u4ea4\u53c9\u9a8c\u8bc1\u5f97\u5206\u4e3a0.79; R2\u662f0.83; \u9884\u6d4b\u7684R2\u4e3a0.80\u3002<\/p>\n

d. \u00a0\u89e3\u91caZ-\u4e9a\u80fa\u6a21\u578b\u672f\u8bed\u3002\u63cf\u8ff0\u50ac\u5316\u5242\u548c\u4e9a\u80fa\u7684\u91cd\u53e0\u7a7a\u95f4\u672f\u8bed\u5f3a\u5316\u4e86\u4e24\u79cd\u51e0\u4f55\u4e9a\u80fa\u7acb\u4f53\u5f02\u6784\u4f53\u5185\u4fdd\u6301\u7c7b\u4f3c\u76f8\u4e92\u4f5c\u7528\u7684\u89c2\u70b9\u3002\u7136\u800c\uff0c\u8be5\u6a21\u578b\u5f3a\u8c03\u4e86\u4e3b\u8981\u6765\u81ea\u4eb2\u6838\u8bd5\u5242\u7684\u7a7a\u95f4\u8d21\u732e\u5bf9\u4e8e\u9ad8\u5bf9\u6620\u9009\u62e9\u6027\u7684\u91cd\u8981\u6027\u3002<\/p>\n

\u8bc4\u4f30\u9884\u6d4b\u80fd\u529b<\/b><\/strong><\/p>\n

\u4f5c\u4e3a\u5de5\u4f5c\u6d41\u7a0b\u7684\u6700\u540e\u4e00\u6b65\uff0c\u6211\u4eec\u8bc4\u4f30\u4e86\u5c06\u7edf\u8ba1\u6a21\u578b\u6355\u83b7\u7684\u5bf9\u6620\u9009\u62e9\u6027\u50ac\u5316\u7684\u673a\u7406\u8f6c\u79fb\u5230\u8bad\u7ec3\u6570\u636e\u96c6\u4e2d\u672a\u5305\u542b\u7684\u771f\u6b63\u4e0d\u540c\u7684\u7ed3\u6784\u57fa\u5e8f\u7684\u80fd\u529b\u3002<\/p>\n

\u56fe 4. \u4f7f\u7528\u53cc\u5c42\u9884\u6d4b\u5de5\u4f5c\u6d41\u7a0b\u8fdb\u884c\u6837\u672c\u5916\u9884\u6d4b\u3002<\/p>\n

\"\"<\/p>\n

\u7efc\u5408\u6a21\u578b\u9996\u5148\u786e\u5b9aE\u6216Z\u8fc7\u6e21\u72b6\u6001\uff0c\u7136\u540e\u4f7f\u7528\u914d\u7f6e\u7279\u5b9a\u6a21\u578b\u6765\u7ec6\u5316\u9884\u6d4b\u3002\u5982\u679c\u53cd\u5e94\u901a\u8fc7E\u6216Z\u8fc7\u6e21\u6001\u8fdb\u884c\u5e76\u4e14\u7531\uff08R\uff09-CPA\u50ac\u5316\uff0c\u5219\u901a\u7528\u80fa\u4ea7\u7269\u8868\u793a\u9884\u6d4b\u7684\u7acb\u4f53\u5316\u5b66\u7ed3\u679c\u3002\u5982\u679c\u4f7f\u7528\uff08S\uff09-CPA\uff0c\u5219\u4ea7\u7269\u7acb\u4f53\u5316\u5b66\u53cd\u8f6c\u3002<\/p>\n

a. \u00a0\u6837\u672c\u5916\u9884\u6d4b\u3002\u5728\u70ef\u9170\u57fa\u4e9a\u80fa\u4e2d\u52a0\u5165\u6c28\u57fa\u7532\u9178\u916f\u548c\u8f6c\u79fb\u7094\u57fa\u916e\u4e9a\u80fa\u7684\u52a0\u6c22\u53cd\u5e94\u7684\u5e94\u7528\u3002 DCM\uff0c\u4e8c\u6c2f\u7532\u70f7;\uff0c\u5ba4\u6e29\uff0825\u00b0C\uff09\u3002<\/p>\n

b. \u00a0\u6837\u672c\u5916\u9884\u6d4b\u548c\u5916\u63a8\u3002\u5728\u82b3\u73af\u76842,4,6\u4f4d\u5177\u6709\u73af\u5df1\u57fa\u7684TCYP\u7684\u9884\u6d4b\u662f\u7528\u4e8e\u5c06\u786b\u9187\u52a0\u6210\u5230\u82ef\u7532\u9170\u4e9a\u80fa\u7684\u9ad8\u9009\u62e9\u6027\u50ac\u5316\u5242\u3002<\/p>\n

\u603b\u7684\u6765\u8bf4\uff0c\u901a\u8fc7\u7ed3\u679c\u4ece\u6837\u672c\u5916\u9884\u6d4b\u5e73\u53f0\u751f\u6210\u7684\u7ed3\u679c\uff0c\u6211\u4eec\u53ef\u4ee5\u5f97\u51fa\u7ed3\u8bba\uff0cE\u548cZ\u805a\u7126\u7684\u76f8\u5173\u6027\u4ea7\u751f\u66f4\u51c6\u786e\u7684\u9884\u6d4b\uff0c\u4f46\u7efc\u5408\u6a21\u578b\u662f\u6709\u4ef7\u503c\u7684\uff0c\u56e0\u4e3a\u5b83\u786e\u5b9a\u5e94\u8be5\u4f7f\u7528\u54ea\u4e2a\u65b9\u7a0b\u3002<\/p>\n

\u7ed3\u8bba:\u00a0<\/b><\/strong><\/p>\n

\u8be5\u4f5c\u8005\u4ecb\u7ecd\u4e86\u4e00\u79cd\u5de5\u4f5c\u6d41\u7a0b\uff0c\u7528\u4e8e\u6a21\u62df\u5404\u79cd\u50ac\u5316\u4f53\u7cfb\u4e2d\u7684\u5bf9\u6620\u9009\u62e9\u6027\u3002\u8be5\u65b9\u6cd5\u7684\u4ef7\u503c\u5728\u4e8e\u53ef\u4ee5\u8003\u8651\u590d\u6742\u7684\u53cd\u5e94\u6761\u4ef6\u5e76\u6210\u529f\u8bc4\u4f30\u591a\u79cd\u4e0d\u540c\u7684\u53cd\u5e94\u3002\u4f7f\u7528\u6db5\u76d6\u8bb8\u591a\u53cd\u5e94\u7684\u5355\u4e00\u6a21\u578b\u6765\u5173\u8054\u548c\u9884\u6d4b\u5bf9\u6620\u9009\u62e9\u6027\u7684\u80fd\u529b\u8868\u660e\uff0c\u4e00\u822c\u8fc7\u6e21\u6001\u7279\u5f81\u5728\u6574\u4e2a\u53cd\u5e94\u8303\u56f4\u5185\u57fa\u672c\u76f8\u4f3c\uff0c\u5141\u8bb8\u5c06\u89c2\u5bdf\u5230\u7684\u53cd\u5e94\u6761\u4ef6\u4ece\u4e00\u4e2a\u53cd\u5e94\u8f6c\u79fb\u5230\u53e6\u4e00\u4e2a\u53cd\u5e94\u3002\u8be5\u53d1\u73b0\u8868\u660e\u5728\u4e0d\u5bf9\u79f0\u50ac\u5316\u4e2d\u53ef\u80fd\u7684\u4e00\u822c\u73b0\u8c61\uff0c\u7531\u6b64\u53ef\u4ee5\u53d1\u73b0\u5f53\u66b4\u9732\u4e8e\u7c7b\u4f3c\u7684\u53cd\u5e94\u6761\u4ef6\u65f6\uff0c\u5404\u79cd\u8f6c\u5316\u4ee5\u76f8\u540c\u7684\u65b9\u5f0f\u8fdb\u884c\u3002\u901a\u8fc7\u673a\u5236\u7279\u5b9a\u76f8\u5173\u6027\u7684\u53d1\u5c55\uff0c\u53ef\u4ee5\u63ed\u793a\u8fd9\u79cd\u53cd\u5e94\u76f8\u4f3c\u6027\u548c\u53cd\u5e94\u7279\u5b9a\u673a\u5236\u539f\u7406\u3002<\/p>\n

\u63a8\u8350\u7406\u7531:<\/b><\/strong><\/p>\n

\u00a0<\/b><\/strong>\u9884\u6d4b\u53cd\u5e94\u9009\u62e9\u6027\u7684\u8ba1\u7b97\u6a21\u578b\u901a\u5e38\u4ec5\u5bf9\u7279\u5b9a\u53cd\u5e94\u7c7b\u578b\u548c\u8f83\u7a84\u8303\u56f4\u7684\u53cd\u5e94\u7ec4\u5206\u662f\u51c6\u786e\u7684\u3002\u9009\u62e9\u6027\u662f\u5316\u5b66\u5408\u6210\u7684\u5173\u952e\u3002\u5982\u679c\u5408\u6210\u53cd\u5e94\u4e0d\u662f\u9009\u62e9\u6027\u7684\uff0c\u5b83\u4e0d\u80fd\u63d0\u4f9b\u6240\u9700\u4ea7\u7269\u7684\u826f\u597d\u4ea7\u7387\uff0c\u5e76\u4e14\u9700\u8981\u7e41\u7410\u7684\u7eaf\u5316\u8fc7\u7a0b\u3002 \u56e0\u6b64\uff0c\u5316\u5b66\u5bb6\u4eec\u4e00\u76f4\u5728\u5bfb\u627e\u9884\u6d4b\u5316\u5b66\u53cd\u5e94\u9009\u62e9\u6027\u7684\u65b9\u6cd5\u3002\u6784\u5efa\u8ba1\u7b97\u6a21\u578b\u662f\u53ef\u884c\u7684\uff0c\u4f46\u662f\u5b83\u4eec\u7684\u5f00\u53d1\u662f\u8d39\u529b\u7684\uff0c\u5e76\u4e14\u5b83\u4eec\u901a\u5e38\u4ec5\u9650\u5b9a\u4e8e\u7279\u5b9a\u7684\u53cd\u5e94\u7c7b\u578b\u3002\u800cMatthew S. Sigman\u6559\u6388\u8bfe\u9898\u7ec4\u62a5\u9053\u4e86\u4e00\u79cd\u66f4\u52a0\u901a\u7528\u7684\u8ba1\u7b97\u6a21\u578b\uff0c\u8fd9\u5bf9\u672a\u6765\u5408\u6210\u53cd\u5e94\u9009\u62e9\u6027\u7684\u9884\u6d4b\u505a\u51fa\u4e86\u975e\u5e38\u91cd\u8981\u7684\u8d21\u732e\u3002<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/b><\/strong><\/p>\n

1. DeLuca, R. J.; Stokes, B. J.; Sigman, M. S.\u00a0Pure Appl. Chem.\u00a02014,\u00a086, 395.\u00a0<\/p>\n

2. Sigman, M. S.; Harper, K. C.; Bess, E. N.; Milo,\u00a0 Chem. Res.2016,\u00a049, 1292.<\/p>\n

3. Hickey, D. P.; Minteer, S. D.; Sigman, M. S. Am. Chem. Soc. 2015,\u00a0137, 16179.<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/b><\/strong>https:\/\/www.nature.com\/articles\/s41586-019-1384-z<\/p>\n

\u672c\u6587\u7531Lion\u4f9b\u7a3f\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1: tougao@cailiaoren.com.<\/p>\n

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\u4f5c\u8005\u4ecb\u7ecd\uff1a Matthew S. Sigman\u662f\u7f8e\u56fd\u6709\u673a\u5316\u5b66\u5bb6\uff0c\u5e08\u627fE. N. Jacobsen\uff0c\u73b0\u4e3a\u72b9\u4ed6\u5927\u5b66\u6559\u6388\u3002 \u7ecf\u5386\uff1a 1992\u7d22\u8bfa\u9a6c\u5dde\u7acb\u5927\u5b66\uff08Calif…<\/p>\n","protected":false},"author":10213,"featured_media":181439,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[],"class_list":["post-181437","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/181437"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/10213"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=181437"}],"version-history":[{"count":5,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/181437\/revisions"}],"predecessor-version":[{"id":182097,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/181437\/revisions\/182097"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/media\/181439"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=181437"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=181437"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=181437"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}