{"id":186638,"date":"2019-09-30T06:30:51","date_gmt":"2019-09-29T22:30:51","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=186638"},"modified":"2019-09-29T20:05:54","modified_gmt":"2019-09-29T12:05:54","slug":"%e6%ad%a6%e6%b1%89%e5%a4%a7%e5%ad%a6%e6%98%86%e5%a3%ab%e5%85%b0%e5%a4%a7%e5%ad%a6adv-mater-%ef%bc%9a%e7%ba%b3%e7%b1%b3%e6%8a%80%e6%9c%af%e5%9c%a8%e9%aa%a8%e5%85%b3%e8%8a%82%e7%82%8e%e6%b2%bb","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=186638","title":{"rendered":"\u6b66\u6c49\u5927\u5b66&\u6606\u58eb\u5170\u5927\u5b66Adv. Mater.\uff1a\u7eb3\u7c73\u6280\u672f\u5728\u9aa8\u5173\u8282\u708e\u6cbb\u7597\u7684\u8fdb\u5c55\u2014\u63d0\u9ad8\u5185\u6e90\u6027\u900f\u660e\u8d28\u9178\u7684\u5408\u6210"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/b><\/strong><\/h3>\n

\u9aa8\u5173\u8282\u75c5(osteoarthritis, OA) \u662f\u5173\u8282\u9000\u884c\u6027\u75be\u75c5\uff0c\u7814\u7a76\u5df2\u8bc1\u5b9e\u4e0e\u708e\u75c7\u5bc6\u5207\u76f8\u5173\uff0c\u5e76\u4e14\u5173\u8282\u8154\u5185\u9ad8\u5206\u5b50\u900f\u660e\u8d28\u9178(hyaluronic acid, HA)\u542b\u91cf\u964d\u4f4e\u662f\u5176\u91cd\u8981\u7684\u6539\u53d8\u4e4b\u4e00\u3002\u4e34\u5e8a\u4e0a\uff0c\u5173\u8282\u8154\u5185\u6ce8\u5c04\u9ad8\u5206\u5b50\u900f\u660e\u8d28\u9178\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u9aa8\u5173\u8282\u708e\u6cbb\u7597\uff0c\u8fbe\u5230\u6da6\u6ed1\u5173\u8282\uff0c\u4fc3\u8fdb\u9aa8\u8d28\u4fee\u590d\u7684\u76ee\u7684\u3002\u4f46\u76ee\u524d\u4e34\u5e8a\u4e0a\u6ce8\u5c04\u7684\u5916\u6e90\u6027\u900f\u660e\u8d28\u9178\u964d\u89e3\u901f\u5ea6\u5feb\uff0c\u9700\u8981\u591a\u6b21\u6ce8\u5c04\uff0c\u589e\u52a0\u60a3\u8005\u8eab\u5fc3\u75db\u82e6\u3002\u4e14\u5916\u6e90\u6027\u900f\u660e\u8d28\u9178\u5927\u591a\u6765\u6e90\u4e8e\u7ec6\u83cc\uff0c\u5305\u542b\u9ad8\u5206\u5b50\u91cf\u548c\u4f4e\u5206\u5b50\u91cf\u900f\u660e\u8d28\u9178\uff0c\u800c\u4f4e\u5206\u5b50\u91cf\u900f\u660e\u8d28\u9178\u53ef\u5f15\u8d77\u9aa8\u8d28\u7834\u574f\u3002\u4fc3\u8fdb\u5173\u8282\u5185\u673a\u4f53\u81ea\u8eab\u5185\u6e90\u6027\u9ad8\u5206\u5b50\u900f\u660e\u8d28\u9178\u7684\u5206\u6ccc\u4e3a\u9aa8\u5173\u8282\u75c5\u7684\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u601d\u8def\u3002\u673a\u4f53\u5185\u900f\u660e\u8d28\u9178\u4e3b\u8981\u662f\u5728\u5173\u8282\u6ed1\u819c\u7ec6\u80de\u5185\u7531\u900f\u660e\u8d28\u9178\u5408\u6210\u91762(hyaluronic acid synthetic enzyme II, HAS2)\u5408\u6210\u7684\uff0c\u5982\u4f55\u63d0\u9ad8\u6ed1\u819c\u7ec6\u80de\u5185HAS2\u7684\u6c34\u5e73\u4e00\u76f4\u662f\u4e2a\u6311\u6218\u3002\u968f\u7740\u6750\u6599\u5b66\u548c\u7eb3\u7c73\u79d1\u6280\u7684\u53d1\u5c55\uff0c\u4ecb\u5b54\u6c27\u5316\u7845\u7eb3\u7c73\u6750\u6599(Mesoporous silica nanoparticle,\u7b80\u79f0MSN)\u7531\u4e8e\u5176\u5177\u6709\u86cb\u767d\u88c5\u8f7d\u91cf\u9ad8\uff0c\u751f\u7269\u76f8\u5bb9\u6027\u597d\u3001\u4ecb\u5b54\u5b54\u5f84\u5c3a\u5bf8\u53ef\u8c03\u4ee5\u53ca\u8868\u9762\u6613\u4e8e\u6709\u673a\u57fa\u56e2\u6539\u6027\u7b49\u4f18\u70b9\u88ab\u89c6\u4e3a\u7406\u60f3\u7684\u86cb\u767d\u836f\u7269\u8f7d\u4f53\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/b><\/strong><\/h3>\n

\u6b66\u6c49\u5927\u5b66\u9f99\u661f\u6559\u6388\uff0c\u6606\u58eb\u5170\u5927\u5b66\u4f59\u627f\u5fe0\u6559\u6388\u548c\u5f90\u7eaf\u9ad8\u7ea7\u7814\u7a76\u5458\u4f7f\u7528\u65b0\u578b\u4ecb\u5b54\u6c27\u5316\u7845\u7eb3\u7c73\u6750\u6599MSN-CC\u8f6c\u8fd0HAS2\uff0c\u4ee5\u63d0\u4f9b\u5185\u6e90\u6027\u9ad8\u5206\u5b50\u900f\u660e\u8d28\u9178\u7684\u5408\u6210\u3002MSN-CC\u5177\u6709\u5927\u5b54\u5f84\u9ad8\u5b54\u5bb9\u7684\u7279\u6b8a\u7eb3\u7c73\u7ed3\u6784\uff0c\u53ef\u4ee5\u63d0\u9ad8\u5bf9\u5927\u5206\u5b50\u86cb\u767d\u7684\u8f7d\u836f\u80fd\u529b\uff0c\u540c\u65f6\u63d0\u9ad8\u836f\u7269\u7684\u5229\u7528\u7387\u3002\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u8fd9\u79cd\u751f\u7269\u53ef\u964d\u89e3\u7684\u7eb3\u7c73\u6750\u6599\u80fd\u591f\u9ad8\u6548\u7684\u5c06HAS2\u8f6c\u8fd0\u8fdb\u989e\u4e0b\u988c\u5173\u8282\u6ed1\u819c\u7ec6\u80de\u4e2d\uff0c\u4f7f\u5176\u53d1\u6325\u9ad8\u6548\u5408\u6210\u5185\u6e90\u6027\u9ad8\u5206\u5b50\u900f\u660e\u8d28\u9178\u7684\u529f\u80fd\u3002\u7ecf\u52a8\u7269\u5b9e\u9a8c\u8bc1\u5b9e\uff0c\u8fd9\u79cd\u7eb3\u7c73\u6750\u6599\u5728\u5927\u9f20\u4f53\u5185\u5b89\u5168\u53ef\u964d\u89e3\uff0c\u53ef\u4ee5\u7f13\u89e3\u5e76\u6291\u5236\u9aa8\u5173\u8282\u708e\u7684\u6ed1\u819c\u708e\u75c7\uff0c\u6cbb\u7597\u6548\u679c\u8fdc\u8fdc\u8d85\u8fc7\u540c\u671f\u5bf9\u7167\u7684\u5355\u7eaf\u900f\u660e\u8d28\u9178\u6ce8\u5c04\u6cbb\u7597\u7ec4\u3002\u540c\u65f6\u8fd9\u4e00\u6cbb\u7597\u65b9\u5f0f\u4e5f\u6709\u52a9\u4e8e\u4fee\u590d\u9aa8\u5173\u8282\u708e\u6a21\u578b\u4e2d\u7684\u9aa8\u7f3a\u635f\u3002\u4e0a\u8ff0\u6210\u679c\u4e8e\u8fd1\u65e5\u53d1\u8868\u5728\u671f\u520aAdv. Mater.\u4e0a\uff0c\u5e76\u88ab\u9009\u4e3a\u5c01\u9762\u5de5\u4f5c\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/b><\/strong><\/h3>\n

\u56fe<\/b><\/strong>1.<\/b><\/strong>\u00a0MSN-CC<\/b><\/strong>\u8f6c\u8fd0<\/b><\/strong>HAS2<\/b><\/strong>\u8fdb\u5165\u7ec6\u80de\u7684\u793a\u610f<\/b><\/strong>\u56fe<\/b><\/strong>\u548cMSN-CC\u7684\u7535\u955c\u7ed3\u6784<\/b><\/strong><\/p>\n

\"\"<\/p>\n

A\uff09\u7eb3\u7c73\u9897\u7c92MSN-CC\u901a\u8fc7\u5305\u8f7dHAS2\u8fdb\u5165\u6ed1\u819c\u7ec6\u80de\u7684\u7ed3\u6784\u793a\u610f\u56fe\uff1b<\/p>\n

B\uff09\u7eb3\u7c73\u9897\u7c92MSN-CC\u7684\u900f\u5c04\u7535\u955c\u56fe\uff1b<\/p>\n

C\uff09\u7eb3\u7c73\u9897\u7c92MSN-CC\u7684\u626b\u63cf\u7535\u955c\u56fe\uff1b<\/p>\n

D\uff09\u901a\u8fc7\u7535\u5b50\u65ad\u5c42\u626b\u63cf\u6280\u672f\u91cd\u6784\u7684MSN-CC\u7684\u5b54\u7ed3\u6784\u7684\u793a\u610f\u56fe\u3002<\/p>\n

\u56fe<\/b><\/strong>2.<\/b><\/strong>\u00a0MSN<\/b><\/strong>–<\/b><\/strong>CC\u4e0eTMJOA\u6ed1\u819c\u7ec6\u80de\u5728\u4f53\u5185<\/b><\/strong>\u5916<\/b><\/strong>\u7684\u751f\u7269\u76f8\u5bb9\u6027\u3002<\/b><\/strong><\/p>\n

\"\"<\/p>\n

A\uff0cC\uff09EdU\u7ec6\u80de\u67d3\u8272\u5b9e\u9a8c\u663e\u793aMSN-CC\u5bf9\u6ed1\u819c\u7ec6\u80de\u589e\u6b96\u65e0\u660e\u663e\u5f71\u54cd(\u6d53\u5ea6\u2266200\u03bcg\/mL-1<\/sup>)\u548cEdU\u7ec6\u80de\u67d3\u8272\u5b9a\u91cf\u6570\u636e\uff1b<\/p>\n

B\uff0cD\uff09TUNEL\u67d3\u8272\u6d4b\u5b9a\u548cAnnexin V-FITC\/PI\u53cc\u67d3\u6d41\u5f0f\u7ec6\u80de\u68c0\u6d4b\u663e\u793aMSN-CC(\u6d53\u5ea6\u2266200\u03bcg\/mL-1<\/sup>)\u5bf9\u6ed1\u819c\u7ec6\u80de\u51cb\u4ea1\u65e0\u660e\u663e\u8bf1\u5bfc\u4f5c\u7528\u3002\u767d\u8272\u7bad\u5934\u8868\u793aTUNEL\u67d3\u8272\u5448\u9633\u6027\uff08\u7eff\u8272\uff0c\u6d53\u5ea6=400\u03bcg\/mL-1<\/sup>\uff09\uff1b<\/p>\n

E,F\uff09\u7ec6\u80de\u5468\u671f\u5206\u6790\u8868\u660eMSN-CC-PEI(\u6d53\u5ea6\u2266200\u03bcg\/mL-1<\/sup>)\u5904\u7406\u540e\u7684\u6ed1\u819c\u7ec6\u80de\u5468\u671f\u65e0\u660e\u663e\u5f71\u54cd\uff0c\u9ad8\u4e8e400\u03bcg\/mL-1<\/sup>\u8f7b\u5fae\u8bf1\u5bfcG1\u671f\u963b\u6ede\u3002F\u663e\u793a\u57fa\u4e8eDean-Jett-Fox\u6a21\u578b\u7684\u7ec6\u80de\u5468\u671f\u5b9a\u91cf\u6570\u636e\u7edf\u8ba1\uff1b<\/p>\n

G\uff09\u88f8\u9f20\u76ae\u4e0b\u6ce8\u5c04\u7ecf\u8fc7\u5b9e\u9a8c\u5904\u7406\u540e\u7ec6\u80de\u56e2\u5f62\u6210\u7684\u76ae\u4e0b\u5305\u5757\uff0c\u901a\u8fc7H\uff06E\u67d3\u8272\u663e\u793a\u7ec4\u7ec7\u75c5\u7406\u5b66\u53d8\u5316\uff0c\u7ec6\u80de\u5f62\u6001\u7ec4\u7ec7\u53d8\u5316\u65e0\u660e\u663e\u6539\u53d8\uff0c\u63d0\u793a\u826f\u597d\u7684\u6750\u6599\u751f\u7269\u5b89\u5168\u6027\u548c\u751f\u7269\u76f8\u5bb9\u6027\uff1b<\/p>\n

H\uff09\u88f8\u9f20\u76ae\u4e0b\u5305\u5757\u7684\u751f\u957f\u66f2\u7ebf\uff1b<\/p>\n

I\uff09\u88f8\u9f20\u76ae\u4e0b\u5305\u5757\u91cd\u91cf\u548c\u88f8\u9f20\u4f53\u91cd\u7edf\u8ba1\u3002<\/p>\n

\u56fe3. MSN-CC\u5305\u8f7dHAS2\u8fdb\u5165OA\u6ed1\u819c\u7ec6\u80de\u4e2d\u4fc3\u8fdb\u9ad8\u5206\u5b50\u91cfHA\u7684\u751f\u7269\u5408\u6210\u3002<\/strong><\/p>\n

\"\"<\/p>\n

A\uff0cB\uff09\u6fc0\u5149\u5171\u7126\u626b\u63cf\u663e\u5fae\u955c\u89c2\u5bdf\u663e\u793a\uff0c\u8367\u5149\u6807\u8bb0\u793a\u8e2aMSN-CC-PEI\uff08\u7ea2\u8272\uff0c\u7ea2\u8272\u7bad\u5934\uff09\u6210\u529f\u5305\u8f7dAlexa Fluor 350\u6807\u8bb0\u7684HAS2\uff08\u84dd\u8272\uff0c\u84dd\u8272\u7bad\u5934\uff09\u8fdb\u5165\u6ed1\u819c\u7ec6\u80de\uff0c4h\u5185\u88ab\u7ec6\u80de\u5185\u6db5\u4f53\uff08Lysosome tracker, \u7eff\u8272\uff09\u5305\u88f9\uff0c\u5e7612h\u540e\u9003\u9038\u5185\u6db5\u4f53\u5305\u88f9\uff0c\u86cb\u767d\u91ca\u653e\u7684\u8fc7\u7a0b\uff1b<\/p>\n

C\uff0cD\uff09WB\u68c0\u6d4b\u663e\u793a\u4e0d\u540c\u6761\u4ef6\u4e0b\u6ed1\u819c\u7ec6\u80de\u4e2dHAS2\uff0cCD44\u548cHMGB1\u7684\u86cb\u767d\u8868\u8fbe\u548c\u5b9a\u91cf\u6570\u636e\u7edf\u8ba1\uff1b<\/p>\n

E\uff09ELISA\u6d4b\u5b9a\u6ed1\u819c\u7ec6\u80de\u7684\u7ec6\u80de\u4e0a\u6e05\u6db2\u4e2dHA\u7684\u6d53\u5ea6\uff08ng\/mL-1<\/sup>\uff09\uff1b<\/p>\n

F\uff09HPLC\u68c0\u6d4b\u7ec6\u80de\u4e0a\u6e05\u6db2\u4e2d\u9ad8\u5206\u5b50\u91cfHA\u7684\u5b9a\u91cf\u5206\u6790\u6570\u636e\u3002<\/p>\n

\u56fe<\/b><\/strong>4.\u00a0<\/b>\u52a8\u7269\u5b9e\u9a8c\u52a8\u7269\u6a21\u578b\u4e2d\uff0cMSN-CC\u8f6c\u8fd0HAS2\u5728\u4f53\u5185\u6cbb\u7597\u9aa8\u5173\u8282\u708e\u3002<\/strong><\/p>\n

\"\"<\/p>\n

A\uff09\u52a8\u7269\u5b9e\u9a8c\u6a21\u578b\u7684\u793a\u610f\u56fe\uff1b<\/p>\n

B\uff09\u989e\u4e0b\u988c\u5173\u8282\u8154\u5185\u6ce8\u5c04\u8367\u5149\u6807\u8bb0MSN-CC-PEI\u4f53\u7cfb\u7684\u5927\u9f20\u5c0f\u52a8\u7269\u8fd1\u7ea2\u5916\u6210\u50cf\uff1b<\/p>\n

C\uff09\u4f4e\u6e29\u51b0\u51bb\u8fde\u7eed\u5207\u7247\u663e\u793a\u989e\u4e0b\u988c\u5173\u8282\u5185\u6ce8\u5c04\u5904\u7406\u540e\u8367\u5149MSN-CC-PEI\u7684\u5206\u5e03\uff08\u5982\u767d\u8272\u7bad\u5934\u6240\u793a\uff09<\/p>\n

D\uff0cE\uff0cF\uff09\u901a\u8fc7ELISA\u6d4b\u5b9a\u6cd5\u6d4b\u5b9aTMJ\u6ed1\u6db2\u4e2dHA\uff0cIL-1\u03b2\u548cTNF-\u03b1\u7684\u6d53\u5ea6\uff1b<\/p>\n

G\uff09HE\u67d3\u8272\u548cHAS2\u7684\u514d\u75ab\u7ec4\u7ec7\u5316\u5b66\u67d3\u8272\u663e\u793a\u6cbb\u7597\u540e\u6ed1\u819c\u7684\u7ec4\u7ec7\u75c5\u7406\u5b66\u6539\u53d8\uff1b<\/p>\n

H\uff09microCT\u626b\u63cf\u663e\u793a\u4e0d\u540c\u5904\u7406\u7ec4\u989e\u4e0b\u988c\u5173\u8282\u7684\u77e2\u72b6\u622a\u9762\u56fe\uff0c\u663e\u793a\u9aa8\u8d28\u7834\u574f\u548c\u4fee\u590d\u53d8\u5316\uff082w\uff0c12w\uff09\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/b><\/strong><\/h3>\n

\u4f53\u5916\u548c\u4f53\u5185\u5b9e\u9a8c\u8bc1\u5b9e\u65b0\u578bMSN-CC\u6750\u6599\u9ad8\u6548\u5730\u5c06\u900f\u660e\u8d28\u9178\u5408\u6210\u9176\u8fd0\u8f7d\u8fdb\u5165\u9aa8\u5173\u8282\u708e\u6ed1\u819c\u7ec6\u80de\uff0c\u5b9e\u73b0\u5927\u5206\u5b50\u86cb\u767d\u6709\u6548\u88c5\u8f7d\u8fdb\u5165\u7ec6\u80de\u7684\u8fc7\u7a0b\uff0c\u540c\u65f6\u4fdd\u8bc1\u8be5\u5927\u5206\u5b50\u86cb\u767d\u7684\u751f\u7269\u5b66\u6d3b\u6027\u5e76\u53d1\u6325\u529f\u80fd\u3002\u8fd9\u4e00\u8fc7\u7a0b\u6709\u6548\u4fc3\u8fdb\u5185\u6e90\u6027\u9ad8\u5206\u5b50\u91cf\u900f\u660e\u8d28\u9178\u7684\u5408\u6210\u548c\u5206\u6ccc\uff0c\u5927\u5927\u4f18\u5316\u4e86\u4f20\u7edf\u900f\u660e\u8d28\u9178\u591a\u6b21\u53cd\u590d\u6ce8\u5c04\u6cbb\u7597\u9aa8\u5173\u8282\u708e\u7684\u65b9\u5f0f\uff0c\u5b9e\u73b0\u4e86\u6291\u5236\u708e\u75c7\u8fdb\u5c55\uff0c\u4fc3\u8fdb\u9aa8\u5173\u8282\u708e\u6ed1\u819c\u548c\u9aa8\u7ec4\u7ec7\u75c5\u53d8\u4fee\u590d\u7684\u6cbb\u7597\u76ee\u7684\u3002\u8fd9\u4e00\u5de5\u4f5c\u4e3a\u9ad8\u6548\u5316\u6cbb\u7597\u9aa8\u5173\u8282\u75c5\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u548c\u624b\u6bb5\u3002\u6b66\u6c49\u5927\u5b66\u535a\u58eb\u751f\u674e\u6167\u654f\u4e3a\u8bba\u6587\u7b2c\u4e00\u4f5c\u8005\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/b><\/strong><\/h3>\n

Nanotherapy in Joints: Increasing Endogenous Hyaluronan Production by Delivering Hyaluronan Synthase 2<\/b><\/u><\/strong><\/a>\u00a0<\/b><\/strong>(Adv. Mater.\uff0c2019\uff0cDOI: 10.1002\/adma.201904535)<\/p>\n

\u00a0\u672c\u6587\u7531\u6606\u58eb\u5170\u5927\u5b66\u548c\u6b66\u6c49\u5927\u5b66\u8bfe\u9898\u7ec4<\/strong>\u4f9b\u7a3f\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1: tougao@cailiaoren.com.<\/p>\n

\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaorenVIP.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u9aa8\u5173\u8282\u75c5(osteoarthritis, OA) \u662f\u5173\u8282\u9000\u884c\u6027\u75be\u75c5\uff0c\u7814\u7a76\u5df2\u8bc1\u5b9e\u4e0e\u708e\u75c7\u5bc6\u5207\u76f8\u5173\uff0c\u5e76\u4e14\u5173\u8282\u8154\u5185\u9ad8\u5206\u5b50\u900f\u660e\u8d28\u9178(hyaluronic aci…<\/p>\n","protected":false},"author":10213,"featured_media":186639,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[],"class_list":["post-186638","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/186638"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/10213"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=186638"}],"version-history":[{"count":6,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/186638\/revisions"}],"predecessor-version":[{"id":186665,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/186638\/revisions\/186665"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/media\/186639"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=186638"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=186638"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=186638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}