{"id":193466,"date":"2020-01-05T06:14:47","date_gmt":"2020-01-04T22:14:47","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=193466"},"modified":"2020-01-04T22:15:05","modified_gmt":"2020-01-04T14:15:05","slug":"adv-mater-%ef%bc%9a%e5%a4%9a%e9%85%9a%e9%87%91%e5%b1%9e%e8%81%94%e5%90%88%e7%ba%b3%e7%b1%b3%e8%8d%af%e7%89%a9%e7%94%a8%e4%ba%8e%e5%8c%96%e7%96%97%e4%b8%8e%e5%8c%96%e5%ad%a6%e5%8a%a8%e5%8a%9b%e5%ad%a6","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=193466","title":{"rendered":"Adv. Mater.\uff1a\u591a\u915a\u91d1\u5c5e\u8054\u5408\u7eb3\u7c73\u836f\u7269\u7528\u4e8e\u5316\u7597\u4e0e\u5316\u5b66\u52a8\u529b\u5b66\u7597\u6cd5\u534f\u540c\u6297\u80bf\u7624"},"content":{"rendered":"<p><strong>\u3010\u7814\u7a76\u80cc\u666f\u3011<\/strong><\/p>\n<p>\u5316\u5b66\u7597\u6cd5\u5728\u4e34\u5e8a\u4e2d\u88ab\u5e7f\u6cdb\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u764c\u75c7\uff0c\u4f46\u662f\u5176\u4e34\u5e8a\u5e94\u7528\u53d7\u5230\u80bf\u7624\u8010\u836f\u6027\u7684\u4e25\u91cd\u9650\u5236\uff0c\u4ee5\u53ca\u5bf9\u4e8e\u764c\u7ec4\u7ec7\u7684\u9009\u62e9\u6027\u5dee\u7684\u4e0d\u5229\u5f71\u54cd\u3002\u5df2\u7ecf\u5f00\u53d1\u7684\u7eb3\u7c73\u836f\u7269\u53ef\u4ee5\u901a\u8fc7\u4e3b\u52a8\u9776\u5411\u6216\u88ab\u52a8\u9776\u5411\u6765\u5b9e\u73b0\u80bf\u7624\u7279\u5f02\u6027\u9012\u9001\uff0c\u7136\u540e\u5176\u6cbb\u7597\u6548\u679c\u4e5f\u4e0d\u80fd\u4ee4\u4eba\u6ee1\u610f\u3002\u76ee\u524d\u591a\u79cd\u6cbb\u7597\u65b9\u5f0f\u534f\u540c\u6297\u80bf\u7624\u5177\u6709\u4f18\u8d8a\u7684\u53d1\u5c55\u524d\u666f\uff0c\u5176\u4e2d\u5e38\u7528\u7684\u57fa\u4e8e\u82ac\u987f\u5316\u5b66\u7684\u5316\u5b66\u52a8\u529b\u7597\u6cd5\uff08CDT\uff09\u9010\u6e10\u6210\u4e3a\u4e00\u79cd\u65b0\u578b\u7684\u764c\u75c7\u6cbb\u7597\u624b\u6bb5\u3002\u5236\u5907\uff0c\u53ef\u4ee5\u901a\u8fc7\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u7279\u5b9a\u523a\u6fc0\u9009\u62e9\u6027\u5730\u91ca\u653e\u548c\u6fc0\u6d3b\u7eb3\u7c73\u5236\u5242\uff0c\u540c\u65f6\u7ed3\u5408\u94c2\u5316\u5b66\u6cbb\u7597\u5242\u548cFenton\u53cd\u5e94\u50ac\u5316\u5242\u7684\u7eb3\u7c73\u5236\u5242\u662f\u975e\u5e38\u6709\u610f\u4e49\u7684\u4e14\u5177\u6709\u6311\u6218\u6027\u7684\u3002\u4e0e\u65e0\u673a\u6cbb\u7597\u5b66\u4e0d\u540c\uff0c\u7531\u6709\u673a\u7ed3\u6784\u5355\u5143\u6784\u5efa\u7684\u7eb3\u7c73\u836f\u7269\u5177\u6709\u65e0\u4e0e\u4f26\u6bd4\u7684\u4f18\u52bf\uff0c\u5305\u62ec\u751f\u7269\u76f8\u5bb9\u6027\u3001\u751f\u7269\u964d\u89e3\u6027\u3001\u9ad8\u8f7d\u836f\u91cf\u548c\u523a\u6fc0\u54cd\u5e94\u6027\uff0c\u5728\u4e34\u5e8a\u8f6c\u5316\u4e2d\u663e\u793a\u51fa\u5e7f\u9614\u7684\u524d\u666f\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c<strong>\u90d1\u5dde\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\u4f59\u7956\u6c5f\u6559\u6388\u3001\u961a\u5168\u7a0b\u6559\u6388\u4e0e\u6d59\u6c5f\u5927\u5b66\u6bdb\u5ce5\u4f1f\u6559\u6388<\/strong>\u8054\u5408\u4f7f\u7528\u513f\u8336\u7d20-3-\u6ca1\u98df\u5b50\u9178\u916f\uff08EGCG\uff09\uff0c\u915a\u7c7b\u94c2\uff08IV\uff09\u524d\u836f\uff08Pt-OH\uff09\u548c\u591a\u915a\u6539\u6027\u5d4c\u6bb5\u5171\u805a\u7269\uff08PEG-<em>b<\/em>-PPOH\uff09\u6784\u5efa\u4e86\u5177\u6709\u9ad8\u8d1f\u8f7d\u80fd\u529b\u7684\u6709\u673a\u6cbb\u7597\u7eb3\u7c73\u836f\u7269\uff08PTCG NPs\uff09\u3002PTCG NPs\u5728\u5faa\u73af\u8fc7\u7a0b\u4e2d\u7684\u9ad8\u5ea6\u7a33\u5b9a\u6027\u6e90\u4e8e\u5b83\u4eec\u4e0e\u91d1\u5c5e\u548c\u591a\u915a\u7684\u5f3a\u76f8\u4e92\u4f5c\u7528\uff0c\u5e76\u4e14\u5728\u7ec6\u80de\u5185\u5316\u540e\u5b9e\u73b0\u4e86\u6709\u6548\u7684\u836f\u7269\u91ca\u653e\u3002\u6fc0\u6d3b\u7684\u987a\u94c2\u901a\u8fc7\u7ea7\u8054\u53cd\u5e94\u63d0\u9ad8\u7ec6\u80de\u5185H<sub>2<\/sub>O<sub>2<\/sub>\u7684\u6c34\u5e73\u3002\u901a\u8fc7\u94c1\u57faFenton\u53cd\u5e94\u53ef\u8fdb\u4e00\u6b65\u5229\u7528\u5b83\u6765\u4ea7\u751f\u5267\u6bd2\u7684\u6d3b\u6027\u6c27\u3002\u4f53\u5916\u548c\u4f53\u5185\u7814\u7a76\u8868\u660e\uff0c\u5316\u5b66\u7597\u6cd5\u548c\u5316\u5b66\u52a8\u529b\u5b66\u7597\u6cd5\u7684\u7ec4\u5408\u53ef\u5b9e\u73b0\u51fa\u8272\u7684\u6297\u764c\u529f\u6548\u3002\u540c\u65f6\uff0c\u901a\u8fc7\u8fd9\u79cd\u7eb3\u7c73\u914d\u65b9\u907f\u514d\u4e86\u94c2\u7c7b\u836f\u7269\u9762\u4e34\u7684\u5168\u8eab\u6bd2\u6027\u3002\u8fd9\u9879\u5de5\u4f5c\u4e3a\u5f00\u53d1\u7528\u4e8e\u7ea7\u8054\u764c\u75c7\u6cbb\u7597\u7684\u5148\u8fdb\u7eb3\u7c73\u836f\u7269\u63d0\u4f9b\u4e86\u6709\u524d\u666f\u7684\u7b56\u7565\u3002\u8be5\u6587\u7ae0\u8fd1\u65e5\u4ee5\u9898\u4e3a\u201c<strong>A Metal\u2013Polyphenol-Coordinated Nanomedicine for Synergistic Cascade Cancer Chemotherapy and Chemodynamic Therapy<\/strong>\u201d\u53d1\u8868\u5728\u77e5\u540d\u671f\u520a<strong>Adv. Mater.<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001\u7eb3\u7c73\u6750\u6599\u5236\u5907\u53ca\u7ec6\u80de\u4f5c\u7528\u8fc7\u7a0b\u793a\u610f\u56fe<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-193467\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/1-56.jpg\" alt=\"\" width=\"600\" height=\"407\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/1-56.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/1-56-300x204.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u7528\u4e8e\u5236\u5907PTCG NPs\u7684\u7ed3\u6784\u5355\u5143\u7684\u5316\u5b66\u7ed3\u6784\u548c\u5361\u901a\u63d2\u56fe\u3002<\/p>\n<p>\uff08b\uff09\u901a\u8fc7EPR\u6548\u5e94\u4ee5\u53ca\u968f\u540e\u7684\u7ec6\u80de\u5185\u5316\uff0cPTCG NPs\u5728\u80bf\u7624\u4e2d\u7684\u9ad8\u5ea6\u84c4\u79ef\u53ca\u4f5c\u7528\u8fc7\u7a0b\u793a\u610f\u56fe\u3002<\/p>\n<p><strong>\u56fe\u4e8c\u3001<\/strong><strong>EAPV<\/strong><strong>\u7684\u5316\u5b66\u7269\u7406\u8868\u5f81<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-193468\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/2-58.jpg\" alt=\"\" width=\"600\" height=\"358\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/2-58.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/2-58-300x179.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a-b\uff09\u901a\u8fc7\u8c03\u8282PEG-b-PPOH\u548cEGCG\u548cPt-OH\u7684\u6bd4\u4f8b\u5236\u5f97\u7684\u7eb3\u7c73\u9897\u7c92\u968f\u8d1f\u8f7d\u836f\u7269\u53d8\u5316\u7684\u88c5\u8f7d\u6548\u7387\uff08a\uff09\u548c\u5e73\u5747\u76f4\u5f84\uff08b\uff09\u3002<\/p>\n<p>\uff08c\uff09\u5206\u522b\u5305\u542b\uff1a\uff08I\uff09PTCG NPs\uff0c\uff08II\uff09FeCl<sub>3<\/sub>\u6216\uff08III\uff09PEG-b-PPOH\u7684\u6eb6\u6db2\u7684UV-vis\u5149\u8c31\u3002<\/p>\n<p>\uff08d\uff09PTCG NPs\uff08EGCG\uff1aPt-OH = 1\uff1a4\uff09\u5728PBS\u4e2d\u7684DLS\u3002<\/p>\n<p>\uff08e\uff09\u7531EGCG\u548cPEG-b-PPOH\u81ea\u7ec4\u88c5\u7684EGCG NPs\u7684TEM\u56fe\u50cf\u3002<\/p>\n<p>\uff08f\uff09\u7531Pt-OH\u548cPEG-b-PPOH\u7ec4\u88c5\u7684Pt-OH NPs\u7684TEM\u56fe\u50cf\u3002<\/p>\n<p>\uff08g\uff09\u7531EGCG\uff0cPt-OH\u548cPEG-b-PPOH\u81ea\u7ec4\u88c5\u7684PTCG NPs\u7684TEM\u56fe\u50cf\uff08EGCG\uff1aPt-OH = 1\uff1a4\uff09\u3002<\/p>\n<p>\uff08h\uff09\u5728pH\u503c\u4e3a5.0\u7684\u542b\u67095.00\u00d710<sup>-3<\/sup> M GSH\u7684\u7f13\u51b2\u6db2\u4e2d\u5b75\u80b224 h\u540e\uff0cPTCG NP\u7684TEM\u56fe\u50cf\u3002<\/p>\n<p>\uff08i\uff09\u5728\u4e0d\u540cpH\u503c\u4e0b\u4ecePTCG NPs\u91ca\u653e\u7684EGCG\u3002<\/p>\n<p>\uff08j\uff09\u5728\u6709\/\u65e0GSH\u7684\u60c5\u51b5\u4e0b\uff0c\u4ecePTCG NPs\u4e2d\u91ca\u653e\u7684EGCG\u3002<\/p>\n<p>\uff08k\uff09\u5728\u4e0d\u540cpH\u503c\u4e0b\u4ecePTCG NPs\u91ca\u653e\u7684\u94c2\u3002<\/p>\n<p>\uff08l\uff09\u5728\u6709\/\u65e0GSH\u7684\u60c5\u51b5\u4e0b\uff0c\u4ecePTCG NPs\u4e2d\u91ca\u653e\u51fa\u7684\u94c2\u3002<\/p>\n<p><strong>\u56fe\u4e09\u3001<\/strong><strong>PTCG NPs<\/strong><strong>\u7684\u4f5c\u7528\u673a\u7406\u7814\u7a76<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-193469\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/3-60.jpg\" alt=\"\" width=\"600\" height=\"467\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/3-60.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/3-60-300x234.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u4e0ePTCG NPs\u5b75\u80b28\u5c0f\u65f6\u7684Hep G2\u7ec6\u80de\u7684CLSM\u56fe\u50cf\u3002<\/p>\n<p>\uff08b\uff09\u7528\u987a\u94c2\u3001Pt-OH\u6216PTCG NPs\u5904\u7406\u4e0d\u540c\u65f6\u95f4\u540e\u7684Hep G2\u7ec6\u80de\u80de\u5185\u94c2\u542b\u91cf\u3002<\/p>\n<p>\uff08c\uff09\u7528\u4e0d\u540c\u7684\u5236\u5242\u5b75\u80b248 h\u540e\uff0cHep G2\u7ec6\u80de\u7684\u7ec6\u80de\u5b58\u6d3b\u7387\u3002<\/p>\n<p>\uff08d\uff09\u4e0d\u540c\u5b9e\u9a8c\u7ec4Hep G2\u5b75\u80b248\u5c0f\u65f6\u540e\u7ec6\u80de\u51cb\u4ea1\u5206\u6790\u3002<\/p>\n<p>\uff08e\uff09MB\u6eb6\u6db2\u4e0eH<sub>2<\/sub>O<sub>2<\/sub>\u3001PTCG NPs\u6216H<sub>2<\/sub>O<sub>2<\/sub>+PTCG NPs\u53cd\u5e94\u540e\u7684\u7d2b\u5916\u53ef\u89c1\u5149\u8c31\u3002<\/p>\n<p>\uff08f\uff09\u5728FeCl<sub>3<\/sub>\u6216\u4e0d\u540c\u7684pH\u503c\u4e0bPTCG NPs\u5bf9MB\u7684\u65f6\u95f4\u4f9d\u8d56\u6027\u5206\u89e3\u3002<\/p>\n<p>\uff08g\uff09\u4e0d\u540c\u5904\u7406\u540e\u7528DCF\u67d3\u8272\u7684Hep G2\u7ec6\u80de\u7684CLSM\u56fe\u50cf\u3002<\/p>\n<p>\uff08h\uff09\uff08g\uff09\u4e2d\u4e0d\u540c\u5904\u7406\u540e\u7ec6\u80de\u5185ROS\u6c34\u5e73\u7684\u91cf\u5316\u3002<\/p>\n<p><strong>\u56fe\u56db\u3001<\/strong><strong>PTCG NPs<\/strong><strong>\u7684\u4f53\u5185\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u751f\u7269\u5206\u5e03\u5206\u6790<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-193470\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/4-57.jpg\" alt=\"\" width=\"600\" height=\"455\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/4-57.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/4-57-300x228.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09EGCG\u548cPTCG NPs\u6ce8\u5c04\u540eEGCG\u7684\u8840\u6d46\u6d53\u5ea6\u4e0e\u65f6\u95f4\u7684\u5173\u7cfb\u3002<\/p>\n<p>\uff08b\uff09\u6ce8\u5c04Pt-OH\u548cPTCG NPs\u540e\u7684\u8840\u6d46\u94c2\u6d53\u5ea6\u968f\u65f6\u95f4\u7684\u53d8\u5316\u3002<\/p>\n<p>\uff08c-d\uff09\u9759\u8109\u6ce8\u5c04\u540e\u4e0d\u540c\u65f6\u95f4\u7684PTCG NPs\u548c\u987a\u94c2\u7684\u7ec4\u7ec7\u5206\u5e03\u3002<\/p>\n<p>\uff08e\uff09\u901a\u8fc7Gd\u548c\u591a\u915a\u4e4b\u95f4\u7684\u914d\u4f4d\uff0c\u63ba\u5165Gd\u7684PTCG NPs\u7684\u793a\u610f\u56fe\u3002<\/p>\n<p>\uff08f\uff09Gd@PTCG NPs\u6ce8\u5c04\u524d\u540e\u7684\u5c0f\u9f20\u4f53\u5185<em>T<\/em><sub>1<\/sub>\u52a0\u6743\u8f74\u5411MRI\u56fe\u50cf\u3002<\/p>\n<p>\uff08g\uff09\u6ce8\u5c04Gd@PTCG NPs\u6216DTPA-Gd\u540e2h\u300112h\u300124h\u80bf\u7624\u90e8\u4f4dSNR\u6bd4\u7684\u5b9a\u91cf\u5206\u6790\u3002<\/p>\n<p><strong>\u56fe\u4e94\u3001<\/strong><strong>PTCG NPs<\/strong><strong>\u7684<\/strong><strong>\u4f53\u5185\u6297\u80bf\u7624\u4f5c\u7528<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-193471\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/5-43.jpg\" alt=\"\" width=\"600\" height=\"317\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/5-43.jpg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2019\/12\/5-43-300x159.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a-b\uff09\u4e0d\u540c\u5904\u7406\u540eHep G2\u8377\u7624\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\u548c\u751f\u957f\u6291\u5236\u7387\u3002<\/p>\n<p>\uff08c\uff09\u4e0d\u540c\u5904\u7406\u540e\u5c0f\u9f20\u7684\u5b58\u6d3b\u7387\u3002<\/p>\n<p>\uff08d\uff09\u4e0d\u540c\u5904\u7406\u540e\u5c0f\u9f20\u80bf\u7624\u7ec6\u80de\u7684\u51cb\u4ea1\u7387\u3002<\/p>\n<p>\uff08e-i\uff09\u7528\u4e0d\u540c\u914d\u65b9\u5904\u7406\u7684\u5c0f\u9f20\u7684ALP\u3001AST\u3001ALT\u3001CREA\u548cBUN\u7684\u8840\u6db2\u751f\u5316\u6d4b\u8bd5\u3002<\/p>\n<p>\uff08j-k\uff09\u6765\u81ea\u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u7ec4\u7ec7\u7684H\uff06E\u548cTUNEL\u67d3\u8272\u3002I\uff0c\u7a7a\u767d\u7ec4\uff1bII\uff0cEGCG NP\uff1bIII\uff0cEGCG + Pt-OH\uff1bIV\uff0c\u987a\u94c2\uff1bV\uff0cPt-OH NPs\uff1bVI\uff0cPTCG NPs\u3002<\/p>\n<p><strong>\u3010\u7ed3\u8bba\u5c55\u671b\u3011<\/strong><\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u4f5c\u8005\u5229\u7528\u91d1\u5c5e-\u591a\u915a\u914d\u4f4d\u7684\u4f18\u52bf\uff0c\u5236\u5907\u4e86\u4e00\u79cd\u6574\u5408\u4e86EGCG\u548cPt-OH\u7684\u6709\u673a\u6cbb\u7597\u836f\u7269\u7eb3\u7c73\u836f\u7269PTCG NPs\uff0c\u8be5\u7eb3\u7c73\u836f\u7269\u5177\u6709\u8f83\u9ad8\u7684\u8f7d\u836f\u91cf\uff0c\u5728\u751f\u7406\u73af\u5883\u4e2d\u8868\u73b0\u51fa\u51fa\u8272\u7684\u7a33\u5b9a\u6027\u3002\u7ec6\u80de\u5185\u5316\u540e\uff0c\u7eb3\u7c73\u836f\u7269\u7279\u5f02\u6027\u5730\u6253\u5f00\u764c\u7ec6\u80de\u7684\u95f8\u95e8\uff0c\u901a\u8fc7\u7ea7\u8054\u53cd\u5e94\u91ca\u653e\u6297\u764c\u836f\u7269\u5e76\u4ea7\u751fROS\uff0c\u5b9e\u73b0\u5316\u5b66\/\u5316\u5b66\u52a8\u529b\u5b66\u8054\u5408\u6cbb\u7597\u3002\u901a\u8fc7\u7528Gd\u63ba\u6742PTCG NPs\u6765\u76d1\u6d4b\u4f20\u9012\u548c\u91ca\u653e\u884c\u4e3a\uff0c\u5e76\u8d4b\u4e88\u7eb3\u7c73\u836f\u7269\u8bca\u65ad\u80fd\u529b\uff0c\u4ece\u800c\u6210\u529f\u5f15\u5165\u4e86\u6210\u50cf\u529f\u80fd\u3002\u4f53\u5185\u7814\u7a76\u8bc1\u5b9e\u4e86PTCG NPs\u7684\u534f\u540c\u6297\u80bf\u7624\u6027\u80fd\u548c\u51fa\u8272\u7684\u751f\u7269\u76f8\u5bb9\u6027\uff0c\u5177\u6709\u8f83\u5927\u4e34\u5e8a\u8f6c\u5316\u6f5c\u529b\u3002\u4e0e\u7edd\u5927\u591a\u6570\u4f20\u7edf\u836f\u7269\u9012\u9001\u7cfb\u7edf\u5f62\u6210\u9c9c\u660e\u5bf9\u6bd4\u7684\u662f\uff0c\u8fd9\u79cd\u91d1\u5c5e-\u914d\u4f53\u6742\u4ea4\u6781\u5927\u5730\u63d0\u9ad8\u4e86\u6297\u764c\u529f\u6548\uff0c\u5e76\u4e30\u5bcc\u4e86\u6240\u5f97\u7eb3\u7c73\u836f\u7269\u7684\u6cbb\u7597\u529f\u80fd\u3002\u8fd9\u9879\u5f00\u521b\u6027\u7684\u5de5\u4f5c\u4e3a\u5f00\u53d1\u6cbb\u7597\u6027\u7eb3\u7c73\u836f\u7269\u63d0\u4f9b\u4e86\u65b0\u7684\u7b56\u7565\uff0c\u5728\u764c\u75c7\u6cbb\u7597\u9886\u57df\u5177\u6709\u5e7f\u9614\u7684\u53d1\u5c55\u524d\u666f\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/adma.201906024\">A Metal\u2013Polyphenol-Coordinated Nanomedicine for Synergistic Cascade Cancer Chemotherapy and Chemodynamic Therapy<\/a> (<em>Adv. Mater.,<\/em> <strong>2019<\/strong>, DOI: 10.1002\/adma.201906024)<\/p>\n<p>\u672c\u6587\u7531\u5927\u5175\u54e5\u4f9b\u7a3f\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1\uff1a<a href=\"mailto:tougao@cailiaoren.com\">tougao@cailiaoren.com<\/a><\/p>\n<p>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaorenvip.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u7814\u7a76\u80cc\u666f\u3011 \u5316\u5b66\u7597\u6cd5\u5728\u4e34\u5e8a\u4e2d\u88ab\u5e7f\u6cdb\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u764c\u75c7\uff0c\u4f46\u662f\u5176\u4e34\u5e8a\u5e94\u7528\u53d7\u5230\u80bf\u7624\u8010\u836f\u6027\u7684\u4e25\u91cd\u9650\u5236\uff0c\u4ee5\u53ca\u5bf9\u4e8e\u764c\u7ec4\u7ec7\u7684\u9009\u62e9\u6027\u5dee\u7684\u4e0d\u5229\u5f71\u54cd\u3002\u5df2\u7ecf\u5f00\u53d1\u7684\u7eb3\u7c73\u836f\u7269\u53ef\u4ee5\u901a\u8fc7\u4e3b\u52a8&#8230;<\/p>\n","protected":false},"author":1004,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[4282],"class_list":["post-193466","post","type-post","status-publish","format-standard","hentry","category-jiedu","tag-4282"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/193466"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/1004"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=193466"}],"version-history":[{"count":2,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/193466\/revisions"}],"predecessor-version":[{"id":193932,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/193466\/revisions\/193932"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=193466"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=193466"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=193466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}