{"id":198914,"date":"2020-04-10T06:59:05","date_gmt":"2020-04-09T22:59:05","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=198914"},"modified":"2020-04-09T21:18:49","modified_gmt":"2020-04-09T13:18:49","slug":"%e4%b8%ad%e7%a7%91%e9%99%a2%e9%95%bf%e6%98%a5%e5%ba%94%e7%94%a8%e5%8c%96%e5%ad%a6%e7%a0%94%e7%a9%b6%e6%89%80%e6%b1%aa%e5%b0%94%e5%ba%b7%e9%99%a2%e5%a3%ab%e7%a0%94%e7%a9%b6%e5%91%98%e5%92%8c%e4%bb%bb","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=198914","title":{"rendered":"Adv. Mater.\uff1a\u5229\u7528\u4e00\u79cd\u53d1\u5939DNA\u5408\u6210\u7684\u94f6\u7eb3\u7c73\u7c07\u4f5c\u4e3a\u901a\u7528\u53cc\u8f93\u51fa\u751f\u6210\u5668 \u201c\u70b9\u4eae\u201d\u591a\u6837\u4f34\u751fDNA\u903b\u8f91\u95e8\u548c\u7ea7\u8054\u7ebf\u8def"},"content":{"rendered":"

\u3010\u5f15\u8a00<\/strong>\u3011<\/p>\n

\u4e3a\u4e86\u514b\u670d\u4f20\u7edf\u57fa\u4e8e\u7845\u7684\u6570\u5b57\u8bbe\u5907\u7684\u5c40\u9650\u6027\uff0c\u79d1\u5b66\u5bb6\u63d0\u51fa\u5e76\u6784\u5efa\u4e86\u4e30\u5bcc\u591a\u6837\u7684\u5206\u5b50\u903b\u8f91\u95e8\u548c\u903b\u8f91\u7ebf\u8def\u3002\u7531\u4e8e\u8131\u6c27\u6838\u7cd6\u6838\u9178\uff08DNA\uff09\u7684\u72ec\u7279\u4f18\u52bf\uff0c\u57fa\u4e8eDNA\u7684\u903b\u8f91\u4f53\u7cfb\u5df2\u7ecf\u4ece\u57fa\u672c\u903b\u8f91\u95e8\uff08\u662f\uff0c\u6216\uff0c\u4e0e\uff0cIHIBIT\u7b49\uff09\u53d1\u5c55\u5230\u5404\u79cd\u9ad8\u7ea7\u903b\u8f91\u5668\u4ef6\u3002\u867d\u7136\u5728\u8be5\u65b9\u9762\u5df2\u7ecf\u53d6\u5f97\u4e86\u5de8\u5927\u7684\u6210\u5c31\uff0c\u4f46\u4ecd\u6709\u4e00\u4e9b\u91cd\u5927\u95ee\u9898\u5e94\u4e88\u4ee5\u8ba4\u771f\u5bf9\u5f85\u3002\u5927\u91cf\u5177\u6709\u591a\u4e2a\u8f93\u51fa\u4fe1\u53f7\u7684\u903b\u8f91\u5668\u4ef6\u5df2\u7ecf\u88ab\u62a5\u9053\u51fa\u6765\u3002\u5176\u4e2d\u5f88\u591a\u987b\u501f\u52a9\u4e8e\u5171\u4ef7\u6807\u8bb0\u7684\u4fe1\u53f7\u5206\u5b50\uff08\u4f8b\u5982\u67d3\u6599\u6216\u6c27\u5316\u8fd8\u539f\u7269\u8d28\uff09\uff0c\u800c\u8fd9\u79cd\u5171\u4ef7\u6807\u8bb0\u7684\u65b9\u5f0f\u76f4\u63a5\u5bfc\u81f4\u4e86\u65f6\u95f4\u7684\u6d6a\u8d39\u548c\u8f83\u9ad8\u7684\u6210\u672c\u3002\u4e3a\u4e86\u4ea7\u751f\u4e00\u4e2a\u4ee5\u4e0a\u7684\u8f93\u51fa\u4fe1\u53f7\uff0c\u5f88\u591a\u8981\u5728\u5206\u5b50\u903b\u8f91\u4f53\u7cfb\u4e2d\u5f15\u5165\u8bb8\u591a\u5176\u4ed6\u7c7b\u578b\u7684\u7269\u8d28\uff08\u4f8b\u5982\uff0c\u4e0d\u540c\u7684\u67d3\u6599\u548c\u4e0d\u7a33\u5b9a\u7684\u8fc7\u6c27\u5316\u6c22\uff09\uff0c\u8fd9\u4e9b\u7269\u8d28\u589e\u52a0\u4e86\u903b\u8f91\u5e73\u53f0\u7684\u590d\u6742\u6027\uff0c\u6709\u635f\u4e8e\u5176\u91cd\u590d\u6027\uff0c\u800c\u4e14\u975e\u5e38\u4e0d\u5229\u4e8e\u4e0d\u540c\u903b\u8f91\u95e8\u7684\u7ea7\u8054\u7ec4\u88c5\u3002\u53e6\u5916\uff0c\u5bf9\u4e8e\u4e0d\u540c\u903b\u8f91\u95e8\u7684\u6784\u5efa\uff0c\u5f80\u5f80\u9700\u8981\u91cd\u65b0\u8bbe\u8ba1DNA\u5e8f\u5217\uff0c\u8fd9\u4e5f\u5bfc\u81f4\u9ad8\u6210\u672c\u548c\u4f4e\u6548\u7387\u3002\u56e0\u6b64\uff0c\u8feb\u5207\u9700\u8981\u5f00\u53d1\u4e00\u79cd\u7ecf\u6d4e\u6709\u6548\u7684\uff0c\u7b80\u5355\u4e14\u975e\u5171\u4ef7\u7684\u5206\u5b50\u903b\u8f91\u5e73\u53f0\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb<\/strong>\u3011<\/p>\n

\u5728\u6b64DNA\u903b\u8f91\u4f53\u7cfb\u4e2d\uff0c\u5229\u7528\u65b0\u578b\u53d1\u5939DNA\u4e3a\u6a21\u677f\u5408\u6210\u7684\u94f6\u7eb3\u7c73\u7c07\uff08H-AgNCs\uff09\u4f5c\u4e3a\u901a\u7528\u7684\u53cc\u8f93\u51fa\u751f\u6210\u5668\uff0c\u5f97\u5230\u591a\u79cd\u5177\u6709\u76f8\u53cd\u529f\u80fd\u7684\u4f34\u751f\u903b\u8f91\u95e8\uff08CCLGs\uff09 \uff08YES ^ NOT\uff0cOR ^ NOR\uff0cINHIBIT ^ IMPLICATION\uff0cXOR ^ XNOR\u548cMAJORITY ^ MINORITY\uff09\u4ee5\u53ca\u6269\u5c55\u7684\u7ea7\u8054\u903b\u8f91\u7ebf\u8def\uff0c\u4e14\u5176\u4e2d\u4e00\u4e9b\u53ef\u6267\u884c\u7279\u5b9a\u529f\u80fd\uff0c\u4f8b\u5982\u5947\u5076\u751f\u6210\u5668\u4e0e\u68c0\u9a8c\u5668\u3002H-AgNCs\u4f5c\u4e3a\u975e\u5171\u4ef7\u4fe1\u53f7\u7684\u6765\u6e90\uff0c\u5b83\u7684\u5f15\u5165\u907f\u514d\u4e86\u7e41\u7410\u4e14\u6602\u8d35\u7684\u4fee\u9970\u6b65\u9aa4\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cCCLGs\u56e0H-AgNCs\u7684\u53cc\u53d1\u5c04\u6027\u8d28\u5177\u6709\u4e86\u4f34\u751f\u7279\u5f81\uff0c\u8fd9\u79cd\u7279\u5f81\u6709\u52a9\u4e8e\u51cf\u5c11\u8bbe\u8ba1\u591a\u91cd\u903b\u8f91\u95e8\u7684\u65f6\u95f4\u548c\u6210\u672c\u3002\u4e0e\u4ee5\u5f80\u7684\u8bbe\u8ba1\u76f8\u6bd4\uff0c\u6b64\u8bbe\u8ba1\u820d\u53bb\u4e86\u8bb8\u591a\u7269\u8d28\uff08\u4f8b\u5982\u6709\u673a\u67d3\u6599\uff09\u548c\u4e0d\u7a33\u5b9a\u7684\u6210\u5206\uff08\u8fc7\u6c27\u5316\u6c22\uff09\uff0c\u8fd9\u4e0d\u4ec5\u964d\u4f4e\u4e86\u903b\u8f91\u5e73\u53f0\u7684\u590d\u6742\u6027\uff0c\u63d0\u9ad8\u4e86\u903b\u8f91\u64cd\u4f5c\u7684\u53ef\u91cd\u590d\u6027\uff0c\u800c\u4e14\u4f7f\u4e0d\u540cDNA\u5206\u5b50\u903b\u8f91\u7684\u7ec4\u88c5\u8fde\u63a5\u66f4\u52a0\u5bb9\u6613\u3002\u503c\u5f97\u671f\u5f85\u7684\u662f\uff0c\u8fd9\u79cd\u7ecf\u6d4e\u6709\u6548\u7684\u7b56\u7565\u5c06\u6fc0\u53d1\u7814\u7a76\u4eba\u5458\u5f00\u53d1\u66f4\u4e3a\u590d\u6742\u7684\u903b\u8f91\u7cfb\u7edf\uff0c\u4e3a\u5206\u5b50\u8ba1\u7b97\u9886\u57df\u505a\u51fa\u8d21\u732e\u3002\u8be5\u6210\u679c\u4ee5\u9898\u4e3a\u201c<\/strong>Illuminating Diverse Concomitant DNA Logic Gates and Concatenated Circuits with Hairpin DNA-Templated Silver Nanoclusters as Universal Dual-Output Generators<\/strong>\u201d<\/strong>\u53d1\u8868\u5728\u56fd\u9645\u8457\u540d\u671f\u520aAdv. Mater.<\/strong>\u4e0a<\/strong>\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe<\/strong>1.<\/strong>H-AgNCs\u4e0e\u4f34\u751f\u903b\u8f91\u95e8\uff08CCLGs\uff09<\/p>\n

\"\"<\/p>\n

A\uff09\u52a0\u5165DNA\u8f93\u5165IN1\u540e\uff0cH-AgNCs\u53d1\u751f\u6784\u8c61\u548c\u8367\u5149\u53d8\u5316\u7684\u793a\u610f\u56fe<\/p>\n

B\uff09\u5728P\/Mg\u7f13\u51b2\u6db2\u4e2d\u4e0d\u542b\uff08a\uff0ca’\uff09\u6216\u542b\u6709\uff08b\uff0cb’\uff09IN1\u7684H-AgNCs\u7684\u8367\u5149\u5149\u8c31\u56fe<\/p>\n

C\u2013E\uff09\u4e09\u5bf9CCLGs\u4e2d\uff0cH-AgNCs\u5728565nm\u548c630nm\u5904\u7684\u5f52\u4e00\u5316\u8367\u5149\u5f3a\u5ea6<\/p>\n

F\u2013H\uff09\u4e09\u79cd\u7c7b\u578b\u7684\u7ec4\u5408\u903b\u8f91\u7ebf\u8def\u7684\u7b26\u53f7\uff08YES || NOT\uff0cOR || NOR\u548cINH || IMP\uff09<\/p>\n

\u56fe<\/strong>2.<\/strong>XOR ^ XNOR\u903b\u8f91\u95e8\"\"<\/strong><\/p>\n

A\uff09\u4ee5X1\uff08D1\uff09\u548cX2\uff08D2\uff09\u4f5c\u4e3a\u8f93\u5165\u7684XOR ^ XNOR\u903b\u8f91\u95e8\u7684DNA\u53cd\u5e94\u793a\u610f\u56fe\uff0c<\/p>\n

B\uff09\u4e0d\u540c\u8f93\u5165\u7ec4\u5408\u4e0bXOR ^ XNOR\u903b\u8f91\u95e8\u7684\u5f52\u4e00\u5316\u8367\u5149\u5f3a\u5ea6<\/p>\n

C\uff09XOR || XNOR\u7684\u7b26\u53f7<\/p>\n

\u56fe<\/strong>3.<\/strong> \u5947\u5076\u751f\u6210\u5668\uff08Pgs\uff09\u4e0e\u5947\u5076\u68c0\u9a8c\u5668\uff08Pcs\uff09<\/p>\n

\"\"<\/p>\n

A\uff09\u4ece2\u8f93\u5165Pgs\u52303\u8f93\u5165Pcs\u7ea7\u8054\u7ebf\u8def\u7684\u6f14\u5316\u793a\u610f\u56fe<\/p>\n

B\uff09\u4ee5D1\uff08X1\uff09\uff0cD2\uff08TX\uff09\u548cP\uff08X2\uff09\u4f5c\u4e3a\u8f93\u5165\u7684Pcs\u7684DNA\u53cd\u5e94\u793a\u610f\u56fe<\/p>\n

C\uff093\u8f93\u5165Pcs\u6240\u6709\u8f93\u5165\u60c5\u51b5\u4e0b\u7684\u5f52\u4e00\u5316\u8367\u5149\u5f3a\u5ea6<\/p>\n

\u56fe<\/strong>4.<\/strong>MAJ^MIN\u903b\u8f91\u95e8<\/p>\n

\"\"<\/p>\n

A\uff09\u4ee5M1\uff0cM2\u548cM3\u4e3a\u4e09\u8f93\u5165\u7684MAJ^MIN\u903b\u8f91\u95e8\u7684\u8fd0\u7b97\u673a\u5236\u793a\u610f\u56fe<\/p>\n

B\uff09\u4e0d\u540c\u72b6\u6001\u4e0bMAJ ^ MIN\u903b\u8f91\u95e8\u7684\u5f52\u4e00\u5316\u8367\u5149\u5f3a\u5ea6<\/p>\n

C\uff09MAJ || MIN\u7ec4\u5408\u903b\u8f91\u7ebf\u8def\u7684\u7b26\u53f7<\/p>\n

\u3010\u603b\u7ed3\u3011<\/strong><\/p>\n

\u5728\u8fd9\u4e2a\u5de5\u4f5c\u4e2d\uff0c\u4f5c\u8005\u91c7\u7528\u4e00\u79cd\u65b0\u578bDNA\u5206\u5b50\u5939\u5408\u6210\u7684\u94f6\u7eb3\u7c73\u7c07\uff08H-AgNCs\uff09\uff0c\u57fa\u4e8e\u5176\u53cc\u53d1\u5c04\u5f3a\u5ea6\u968f\u5206\u5b50\u5939\u6784\u8c61\u6539\u53d8\u800c\u53d8\u5316\u7684\u7279\u6027\uff0c\u8bbe\u8ba1\u4e86\u591a\u79cd\u7684\u4f34\u751f\u903b\u8f91\u95e8\uff08CCLGs\uff09\u4ee5\u53ca\u5177\u6709\u7279\u5b9a\u529f\u80fd\u7684\u7ea7\u8054\u903b\u8f91\u7ebf\u8def\u3002\u8be5\u5de5\u4f5c\u5229\u7528\u975e\u53d8\u6027\u805a\u4e19\u70ef\u9170\u80fa\u51dd\u80f6\u7535\u6cf3\uff0c\u786e\u8ba4\u4e86\u5177\u4f53\u7684DNA\u6742\u4ea4\u8fc7\u7a0b\uff0c\u540c\u65f6\uff0c\u6240\u6709\u83b7\u5f97\u7684\u8367\u5149\u8f93\u51fa\u5747\u7b26\u5408\u6240\u8981\u6c42\u7684\u903b\u8f91\u89c4\u5219\u3002\u8be5\u903b\u8f91\u4f53\u7cfb\u5177\u6709\u663e\u8457\u7684\u4f18\u52bf\uff0c\u603b\u7ed3\u5982\u4e0b\uff1a1\uff09\u7531\u4e8e\u4f7f\u7528\u4e86H-AgNCs\u4f5c\u4e3a\u975e\u5171\u4ef7\u4fe1\u53f7\u6765\u6e90\uff0c\u907f\u514d\u4e86\u7e41\u7410\u4e14\u6602\u8d35\u7684\u6807\u8bb0\u6b65\u9aa4\uff1b2\uff09\u5f52\u56e0\u4e8eH-AgNCs\u7684\u53cc\u53d1\u5c04\u6027\u8d28\uff0cCCLGs\u7684\u4f34\u751f\u7279\u5f81\u6709\u52a9\u4e8e\u51cf\u5c11\u8bbe\u8ba1\u591a\u91cd\u903b\u8f91\u95e8\u7684\u65f6\u95f4\u548c\u6210\u672c\uff1b3\uff09\u907f\u514d\u4e86\u590d\u6742\u800c\u4e0d\u7a33\u5b9a\u7684\u6210\u5206\uff08\u4f8b\u5982\u6709\u673a\u67d3\u6599\u6216\u8fc7\u6c27\u5316\u6c22\uff09\uff0c\u5e76\u5b9a\u4e49\u4e86\u4e00\u4e2a\u901a\u7528\u9608\u503c\uff0c\u8d4b\u4e88\u4e86DNA\u5206\u5b50\u903b\u8f91\u4f53\u7cfb\u72ec\u7279\u7684\u7279\u6027\uff0c\u4f8b\u5982\u53ef\u91cd\u590d\u6027\u548c\u6613\u4e8e\u96c6\u6210\u3002\u8fd9\u9879\u7814\u7a76\u4e0d\u4ec5\u6269\u5c55\u4e86\u7ecf\u6d4e\u6709\u6548\u903b\u8f91\u4f53\u7cfb\u7684\u84dd\u56fe\uff0c\u800c\u4e14\u8fd8\u5c06\u6fc0\u53d1\u6211\u4eec\u5229\u7528\u65b0\u9896\u7684DNA\u529f\u80fd\u5316\u6750\u6599\u521b\u5efa\u66f4\u52a0\u590d\u6742\u4e0e\u667a\u80fd\u7684\u7f51\u7edc\u4f53\u7cfb\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5<\/strong>\uff1aIlluminating Diverse Concomitant DNA Logic Gates and Concatenated Circuits with Hairpin DNA-Templated Silver Nanoclusters as Universal Dual-Output Generators<\/strong>. Adv. Mater., <\/em>2020<\/strong>, DOI: 10.1002\/adma.201908480.<\/p>\n

\u672c\u6587\u7531tt\u4f9b\u7a3f\u3002\u00a0<\/p>\n

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