{"id":205593,"date":"2020-07-20T06:47:12","date_gmt":"2020-07-19T22:47:12","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=205593"},"modified":"2020-07-19T20:47:33","modified_gmt":"2020-07-19T12:47:33","slug":"%e8%a5%bf%e5%b7%a5%e5%a4%a7%e5%bc%a0%e7%a7%8b%e7%a6%b9%e5%9b%a2%e9%98%9fnano-lett-%ef%bc%9a%e7%ba%b3%e7%b1%b3%e9%85%b6%e5%a2%9e%e5%bc%ba%e5%8f%af%e6%b3%a8%e5%b0%84%e6%b0%b4%e5%87%9d%e8%83%b6%e6%b2%bb","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=205593","title":{"rendered":"\u897f\u5de5\u5927\u5f20\u79cb\u79b9\u56e2\u961fNano Lett.\uff1a\u7eb3\u7c73\u9176\u589e\u5f3a\u53ef\u6ce8\u5c04\u6c34\u51dd\u80f6\u6cbb\u7597\u591a\u836f\u8010\u836f\u83cc\u611f\u67d3\u7684\u7cd6\u5c3f\u75c5\u521b\u9762"},"content":{"rendered":"<p><strong>\u3010\u7814\u7a76\u80cc\u666f\u3011<\/strong><\/p>\n<p>\u7cd6\u5c3f\u75c5\u60a3\u8005\u4f24\u53e3\u6108\u5408\u53d7\u635f\u5728\u5168\u4e16\u754c\u8303\u56f4\u5185\u5bfc\u81f4\u4e86\u663e\u8457\u7684\u53d1\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u3002\u53ef\u6ce8\u5c04\u81ea\u6108\u6c34\u51dd\u80f6\u5177\u6709\u9ad8\u8010\u7528\u6027\u548c\u5fae\u521b\u690d\u5165\u7a0b\u5e8f\uff0c\u7406\u60f3\u5730\u6ee1\u8db3\u4e86\u7ec6\u80de\u8fc1\u79fb\u548c\u589e\u6b96\u7684\u751f\u7269\u5b66\u548c\u5206\u5b50\u4e8b\u4ef6\u7684\u6574\u5408\u8981\u6c42\uff0c\u4e3a\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\u63d0\u4f9b\u4e86\u6709\u5e0c\u671b\u7684\u9009\u62e9\u3002\u7136\u800c\uff0c\u7531\u4e8e\u81ea\u8eab\u6062\u590d\u80fd\u529b\u7684\u9ad8\u5ea6\u6709\u9650\u6027\u548c\u5bf9\u591a\u836f\u8010\u836f\uff08MDR\uff09\u7ec6\u83cc\u611f\u67d3\u7684\u8106\u5f31\u6027\uff0c\u76ee\u524d\u5927\u591a\u6570\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u4f24\u53e3\u6108\u5408\u5728\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u5e38\u5e38\u53d7\u5230\u635f\u5bb3\u3002\u9664\u4e86\u7ec6\u83cc\u611f\u67d3\u5916\uff0c\u6076\u52a3\u7684\u9ad8\u8840\u7cd6\u548c\u6c27\u5316\u5fae\u73af\u5883\u8fdb\u4e00\u6b65\u963b\u788d\u4e86\u7cd6\u5c3f\u75c5\u76ae\u80a4\u521b\u9762\u7684\u6062\u590d\u3002\u5728\u7cd6\u5c3f\u75c5\u7684\u60c5\u51b5\u4e0b\uff0c\u5305\u62ec\u4e2d\u6027\u7c92\u7ec6\u80de\u5728\u5185\u7684\u514d\u75ab\u7ec6\u80de\u4ea7\u751f\u66f4\u591a\u7684\u6d3b\u6027\u6c27\uff08ROS\uff09\uff0c\u5bfc\u81f4\u7cd6\u5c3f\u75c5\u5668\u5b98\u635f\u4f24\u3001\u75a4\u75d5\u5ef6\u957f\u6216\u4f24\u53e3\u4e0d\u6108\u5408\u3002\u6b64\u5916\uff0c\u9ad8\u8840\u7cd6\u53ef\u5bfc\u81f4\u8840\u7ba1\u6536\u7f29\uff0c\u6291\u5236\u8840\u7ba1\u751f\u6210\uff0c\u4ece\u800c\u901a\u8fc7\u963b\u65ad\u6c27\u6c14\u4f9b\u5e94\u963b\u788d\u6108\u5408\u8fc7\u7a0b\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c\u897f\u5317\u5de5\u4e1a\u5927\u5b66\u5f20\u79cb\u79b9\u56e2\u961f\u5f00\u53d1\u4e86\u4e00\u79cd\u53ef\u6ce8\u5c04\u3001\u81ea\u6108\u548c\u7c98\u9644\u7684\u6c34\u51dd\u80f6\uff08FEMI\uff09\uff0c\u7528\u4e8e\u52a0\u901fMDR\u611f\u67d3\u7684\u7cd6\u5c3f\u75c5\u4f24\u53e3\u91cd\u5851\u3002\u5229\u7528EPL\u5305\u8986MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\uff08EM\uff09\u4e0e\u80f0\u5c9b\u7d20\u5305\u5c01\u919bPluronic F127\uff08FCHO\uff09\u80f6\u675f\u7684\u5e2d\u592b\u53cd\u5e94\u5236\u5907\u4e86\u591a\u529f\u80fd\u6c34\u51dd\u80f6\u3002\u5176\u5177\u6709\u5feb\u901f\u51dd\u80f6\u5316\u884c\u4e3a\u548c\u7a33\u5b9a\u7684\u6d41\u53d8\u6027\u80fd\uff0c\u540c\u65f6\uff0c\u901a\u8fc7\u6b63\u7535\u8377\u7684EPL\u548c\u201c\u7eb3\u7c73\u5200\u72b6\u201dMnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u7684\u534f\u540c\u4f5c\u7528\uff0c\u4e5f\u8868\u73b0\u51fa\u975e\u51e1\u7684\u6297\u83cc\u80fd\u529b\u3002FEMI\u6c34\u51dd\u80f6\u8fd8\u8868\u73b0\u51fa\u826f\u597d\u7684\u6b62\u8840\u6027\u80fd\uff0c\u8fd9\u662f\u7531\u4e8e\u5176\u5feb\u901f\u51dd\u80f6\u5316\u548c\u826f\u597d\u7684\u7ec4\u7ec7\u7c98\u9644\u6027\uff0c\u5982\u809d\u810f\u51fa\u8840\u6a21\u578b\u6240\u793a\u3002\u6700\u91cd\u8981\u7684\u662f\uff0c\u5f97\u76ca\u4e8e\u7eb3\u7c73\u9176MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u7684\u9ad8\u50ac\u5316\u6548\u7387\uff0cFEMI\u6c34\u51dd\u80f6\u901a\u8fc7\u50ac\u5316\u5185\u6e90\u6027H<sub>2<\/sub>O<sub>2<\/sub>\u5206\u89e3\u4e3aO<sub>2<\/sub>\u6765\u7f13\u89e3\u6c27\u5316\u5e94\u6fc0\u3002\u540c\u65f6\uff0c\u7531\u4e8e\u9178\u6027\u548c\u6c27\u5316\u6027\u7cd6\u5c3f\u75c5\u7684\u76ae\u80a4\u73af\u5883\uff0c\u8be5pH\u548c\u6c27\u5316\u8fd8\u539f\u53cc\u54cd\u5e94FEMI\u6c34\u51dd\u80f6\u5b9e\u73b0\u4e86\u80f0\u5c9b\u7d20\u7684\u6301\u7eed\u548c\u65f6\u7a7a\u63a7\u5236\u91ca\u653e\u3002\u901a\u8fc7\u540c\u65f6\u6d88\u9664MRSA\u611f\u67d3\u3001\u964d\u4f4e\u9ad8\u8840\u7cd6\u3001\u6539\u5584\u6c27\u5316\u5e94\u6fc0\u548c\u6301\u7eed\u63d0\u4f9b\u6c27\u6c14\uff0cFEMI\u6c34\u51dd\u80f6\u4e3a\u51cf\u8f7b\u708e\u75c7\u3001\u52a0\u901f\u7ec6\u80de\u589e\u6b96\u3001\u4fc3\u8fdb\u8840\u7ba1\u5316\u3001\u4fc3\u8fdb\u8089\u82bd\u7ec4\u7ec7\u5f62\u6210\u548c\u518d\u4e0a\u76ae\u5316\u63d0\u4f9b\u4e86\u6709\u76ca\u7684\u5fae\u73af\u5883\uff0c\u5728\u4f53\u5185\u663e\u793a\u51fa\u663e\u8457\u7684\u52a0\u901f\u7cd6\u5c3f\u75c5\u4f24\u53e3\u6108\u5408\u3002\u8be5\u6587\u7ae0\u8fd1\u65e5\u4ee5\u9898\u4e3a\u201c<strong>Nanoenzyme-Reinforced Injectable Hydrogel for Healing Diabetic Wounds Infected with Multidrug Resistant Bacteria<\/strong>\u201d\u53d1\u8868\u5728\u77e5\u540d\u671f\u520a<strong>Nano Letters<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001<\/strong><strong>FEMI<\/strong><strong>\u6c34\u51dd\u80f6\u5bf9\u611f\u67d3\u591a\u836f\u8010\u836f\u7ec6\u83cc\u7684\u7cd6\u5c3f\u75c5\u521b\u53e3\u6108\u5408\u7684\u793a\u610f\u56fe<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-205594\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/1-1.jpeg\" alt=\"\" width=\"600\" height=\"413\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/1-1.jpeg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/1-1-300x207.jpeg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" 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loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-205595\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/2-1.jpeg\" alt=\"\" width=\"600\" height=\"419\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/2-1.jpeg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/2-1-300x210.jpeg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u7684\u5178\u578bTEM\u56fe\u50cf\u3002<\/p>\n<p>\uff08b\uff09\u5728pH 7.4\u7684\u6c34\u6eb6\u6db2\u4e2d\u6d4b\u5b9a\u4e86EPL\u3001MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u3001EM\u7eb3\u7c73\u7247\u7684Zeta\u7535\u4f4d\u3002<\/p>\n<p>\uff08c\uff09FCHO\u7684\u6838\u78c1\u6c22\u8c31\u3002<\/p>\n<p>\uff08d\uff09F127\u3001F127-SO3\u3001FCHO\u3001MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\uff08NS\uff09\u3001EPL\u3001EM\u548cFEMI\u7684FTIR\u5149\u8c31\u3002<\/p>\n<p>\uff08e\uff09FEMI\u6c34\u51dd\u80f6\u7684\u5178\u578bSEM\u56fe\u50cf\uff0c\u663e\u793a\u4e86\u660e\u663e\u7684\u4e09\u7ef4\u591a\u5b54\u7ed3\u6784\u3002<\/p>\n<p>\uff08f\uff09FEMI\u6c34\u51dd\u80f6\u7684SEM\u653e\u5927\u56fe\u50cf\u548cEDS\u5143\u7d20\u6620\u5c04\u3002<\/p>\n<p>\uff08g\uff09EDS\u6d4b\u5b9a\u4e86FEMI\u6c34\u51dd\u80f6\u4e2dMn\u79bb\u5b50\u7684\u542b\u91cf\u3002<\/p>\n<p>\uff08h\uff09FEM-4\u6c34\u51dd\u80f6\u7684\u50a8\u80fd\u6a21\u91cf\uff08G\u2032\uff09\u548c\u635f\u8017\u6a21\u91cf\uff08G\u3003\uff09\u3002\u63d2\u56fe\uff1aFEM-4\u6c34\u51dd\u80f6\u7684\u6eb6\u80f6-\u51dd\u80f6\u8f6c\u53d8\u7167\u7247\u3002<\/p>\n<p>\uff08i\uff09\u901a\u8fc7\u5bf9FEM-4\u6c34\u51dd\u80f6\u572837\u2103\u4e0b\u8fdb\u884c3\u6b211%\uff5e1000%\u526a\u5207\u5e94\u53d8\u7684G\u2032\u548cG\u3003\u5faa\u73af\u8bd5\u9a8c\uff0c\u8bc4\u4ef7\u4e86FEM-4\u6c34\u51dd\u80f6\u7684\u529b\u5b66\u6027\u80fd\u3002<\/p>\n<p>\uff08j\uff09\u901a\u8fc7\u642d\u63a5\u526a\u5207\u8bd5\u9a8c\u8bc4\u4ef7\u4e86FEM\u6c34\u51dd\u80f6\u5bf9\u76ae\u80a4\u7ec4\u7ec7\u7684\u7c98\u9644\u5f3a\u5ea6\u3002<\/p>\n<p>\uff08k\uff09\u526a\u5207\u901f\u7387\u4e3a0.1\uff5e100 s<sup>-1<\/sup>\u7684FEM\u6c34\u51dd\u80f6\u7684\u7c98\u5ea6\u3002\u63d2\u56fe\uff1aFEM\u6c34\u51dd\u80f6\u901a\u8fc7\u9488\u6ce8\u5c04\u7684\u7167\u7247\u3002<\/p>\n<p><strong>\u56fe\u4e09\u3001\u901a\u8fc7\u51cf\u8f7b\u6c27\u5316\u5e94\u6fc0\u548c\u4ea7\u751f\u6c27\u6c14\uff0c\u63d0\u9ad8\u6210\u7ea4\u7ef4\u7ec6\u80de\u7684\u5b58\u6d3b\u548c\u589e\u6b96\u3002<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-205596\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/3-1.jpeg\" alt=\"\" width=\"600\" height=\"705\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/3-1.jpeg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/3-1-255x300.jpeg 255w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09FEM\u6c34\u51dd\u80f6\u4e2dMnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u50ac\u5316\u6c27\u5316\u5e94\u6fc0\u751f\u6210O<sub>2<\/sub>\u793a\u610f\u56fe\u3002<\/p>\n<p>\uff08b\uff09\u901a\u8fc7\u6d4b\u91cfH<sub>2<\/sub>O<sub>2<\/sub>\u6307\u793a\u5242[Ti(SO<sub>4<\/sub>)<sub>2<\/sub>]\u6eb6\u6db2\u7684\u7d2b\u5916-\u53ef\u89c1\u5438\u6536\u5149\u8c31\uff0c\u8bc4\u4ef7\u4e86MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u5bf9H<sub>2<\/sub>O<sub>2<\/sub>\u7684\u5242\u91cf\u4f9d\u8d56\u6027\u6d88\u9664\u4f5c\u7528\u3002<\/p>\n<p>\uff08c\uff09\u5e94\u7528\u4e0d\u540c\u7eb3\u7c73MnO<sub>2<\/sub>\u6c34\u51dd\u80f6\u540e\u6eb6\u6db2\u4e2d\u6b8b\u7559H<sub>2<\/sub>O<sub>2<\/sub>\u7684\u5b9a\u91cf\u5206\u6790\u3002<\/p>\n<p>\uff08d\uff09\u7528\u5546\u7528\u6c27\u6c14\u8ba1\u8bb0\u5f55\u7684\u7684\u6c27\u6c14\u751f\u6210\u3002\u63d2\u56fe\uff1a\u751f\u6210\u7684O<sub>2<\/sub>\u6c14\u6ce1\u7684\u4ee3\u8868\u6027\u7167\u7247\u3002<\/p>\n<p>\uff08e\uff09\u7528ROS\u63a2\u9488\uff08DCFH-DA\uff09\u76d1\u6d4b\u4e0d\u540c\u5904\u7406\u5bf9L929\u7ec6\u80de\u6c27\u5316\u5e94\u6fc0\u7684\u7f13\u89e3\u4f5c\u7528\u3002<\/p>\n<p>\uff08f\uff09\u7528\u6c27\u63a2\u9488Ru(dpp)<sub>3<\/sub>Cl<sub>2<\/sub>\u5bf9L929\u7ec6\u80de\u8fdb\u884c\u4e0d\u540c\u5904\u7406\u540e\u7684\u7ec6\u80de\u5185O2\u751f\u6210\u5b9e\u9a8c\u8fdb\u884c\u4e86\u9a8c\u8bc1\u3002<\/p>\n<p>\uff08g-h\uff09\u901a\u8fc7\u8ba1\u7b97L929\u7ec6\u80de\u7684\u8367\u5149\u5f3a\u5ea6\uff0c\u5206\u6790\u4e86\u7ec6\u80de\u5185ROS\u6d88\u8017\u548cO<sub>2<\/sub>\u751f\u6210\u7684\u5b9a\u91cf\u7814\u7a76\u3002<\/p>\n<p>\uff08i\uff09pH\u548c\u6c27\u5316\u8fd8\u539f\u53cc\u53cd\u5e94\u80f0\u5c9b\u7d20\u91ca\u653e\u52a8\u529b\u5b66\u3002<\/p>\n<p>\uff08j-k\uff09\u6210\u7ea4\u7ef4\u7ec6\u80de\u4f53\u5916\u6d3b\/\u6b7b\u67d3\u8272\uff08j\uff09\u548c\u7ec6\u80de\u5b58\u6d3b\u60c5\u51b5\uff08k\uff09\u3002<\/p>\n<p><strong>\u56fe\u56db\u3001<\/strong><strong>FEM<\/strong><strong>\u6c34\u51dd\u80f6\u7684\u6297\u83cc\u6027\u80fd\u548c\u6b62\u8840\u6027\u80fd<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-205597\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/4-1.jpeg\" alt=\"\" width=\"600\" height=\"616\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/4-1.jpeg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/4-1-292x300.jpeg 292w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a-b\uff09\u4e0d\u540cEM\u542b\u91cfFEM\u6c34\u51dd\u80f6\u6297\u83cc\u6d3b\u6027\u5206\u6790\u3002<\/p>\n<p>\uff08c\uff09\u4e0d\u540c\u5904\u7406\u540eMRSA\u7ec6\u80de\u7684\u4ee3\u8868\u6027SEM\u56fe\u50cf\u3002<\/p>\n<p>\uff08d\uff09FEM\u6c34\u51dd\u80f6\u5728\u7cd6\u5c3f\u75c5\u5c0f\u9f20\u809d\u51fa\u8840\u6a21\u578b\u4e2d\u6b62\u8840\u80fd\u529b\u793a\u610f\u56fe\u3002<\/p>\n<p>\uff08e\uff09\u5bf9\u7167\u7ec4\uff08\u672a\u6cbb\u7597\uff09\u3001\u7f8e\u7f57\u8d5b\u3001FCHO\u548cFEM\u6c34\u51dd\u80f6\u6cbb\u7597\u7684\u53d7\u635f\u809d\u810f\u7684\u603b\u5931\u8840\u91cf\u3002<\/p>\n<p>\uff08f\uff09\u57280\u30015\u300115\u300130\u300160\u79d2\u7684\u7279\u5b9a\u65f6\u95f4\u8fdb\u884c\u4e0a\u8ff0\u5904\u7406\u7684\u809d\u810f\u4ee3\u8868\u6027\u7167\u7247\u3002<\/p>\n<p><strong>\u56fe\u4e94\u3001<\/strong><strong>FEMI<\/strong><strong>\u6c34\u51dd\u80f6\u901a\u8fc7\u6784\u5efa\u6709\u76ca\u7684\u5fae\u73af\u5883\u4fc3\u8fdb\u7cd6\u5c3f\u75c5\u521b\u9762\u6108\u5408<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-205598\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/5-1.jpeg\" alt=\"\" width=\"600\" height=\"604\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/5-1.jpeg 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/5-1-150x150.jpeg 150w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2020\/07\/5-1-298x300.jpeg 298w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u624b\u672f\u8fc7\u7a0b\u7684\u65f6\u95f4\u7ebf\uff0c\u57fa\u4e8eFEMI\u6c34\u51dd\u80f6\u7684\u6297\u83cc\u884c\u4e3a\uff0c\u548c\u52a0\u901f\u4f24\u53e3\u95ed\u5408\u6027\u80fd\u7684\u793a\u610f\u56fe\u3002<\/p>\n<p>\uff08b\uff09\u5bf9\u7167\u7ec4\u3001\u6297\u751f\u7d20\u6c28\u82c4\u897f\u6797\u3001FCHO\u3001FEM\u548cFEMI\u6c34\u51dd\u80f6\u5904\u7406\u7684\u5c0f\u9f20\u4f24\u53e3\u6108\u5408\u8fc7\u7a0b\u7684\u56fe\u50cf\u3002<\/p>\n<p>\uff08c\uff09\u6bcf\u6b21\u6cbb\u759714\u5929\u5185\u4f24\u53e3\u6108\u5408\u7684\u75d5\u8ff9\u3002<\/p>\n<p>\uff08d\uff09\u4e94\u7ec4\u4e0d\u540c\u65f6\u95f4\u70b9\u7684\u4f53\u5185\u4f24\u53e3\u95ed\u5408\u7387\u3002<\/p>\n<p>\uff08e\uff09\u4e94\u7ec4\u7cd6\u5c3f\u75c5\u5c0f\u9f20\u4e0d\u540c\u65f6\u95f4\u70b9\u8840\u7cd6\u7684\u53d8\u5316\u3002<\/p>\n<p>\uff08f\uff09\u7528ROS\u63a2\u9488\uff08DHE\uff0cDHE\uff09\u76d1\u6d4b\u4e0d\u540c\u5904\u7406\u540e\u521b\u9762\u7684ROS\u6c34\u5e73\u3002<\/p>\n<p>\uff08g\uff09\u6c27\u5316DHE\u8367\u5149\u5f3a\u5ea6\u76f4\u65b9\u56fe\u663e\u793aFEM\u548cFEMI\u6c34\u51dd\u80f6\u4e2dROS\u7684\u6709\u6548\u6d88\u8017\u3002<\/p>\n<p>\uff08h\uff09\u7b2c3\u30017\u300114\u59295\u79cd\u4e0d\u540c\u5904\u7406\u521b\u9762\u518d\u751f\u7684\u7ec4\u7ec7\u5f62\u6001\u5b66\u8bc4\u4ef7\u3002<\/p>\n<p>\uff08i\uff09\u7b2c7\u5929\u5404\u7ec4\u8868\u76ae\u539a\u5ea6\u3002<\/p>\n<p>\uff08j\uff09\u7b2c7\u5929\u548c\u7b2c14\u5929\u518d\u751f\u8840\u7ba1\u3002<\/p>\n<p>\uff08k\uff09\u7b2c14\u5929\u5404\u7ec4\u6bdb\u56ca\u5927\u5c0f\u5bf9\u6bd4\u3002<\/p>\n<p><strong>\u3010\u7ed3\u8bba\u5c55\u671b\u3011<\/strong><\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u4f5c\u8005\u8bbe\u8ba1\u5e76\u9a8c\u8bc1\u4e86\u4e00\u79cd\u5177\u6709\u53ef\u6ce8\u5c04\u6027\u3001\u7c98\u9644\u6027\u3001\u81ea\u6108\u6027\u3001\u6297\u6c27\u5316\u6027\u548c\u6297\u83cc\u6027\u7684FEMI\u6c34\u51dd\u80f6\uff0c\u53ef\u6709\u6548\u4fc3\u8fdb\u591a\u836f\u8010\u836f\u83cc\u611f\u67d3\u7684\u7cd6\u5c3f\u75c5\u4f24\u53e3\u6108\u5408\u3002\u901a\u8fc7\u5f15\u51652D-EM\u7eb3\u7c73\u586b\u6599\u4e0e\u805a\u5408\u7269\u57fa\u4f53\u76f8\u4e92\u4f5c\u7528\uff0c\u5236\u5907\u4e86\u51dd\u80f6\u5316\u901f\u5ea6\u5feb\u3001\u6d41\u53d8\u6027\u80fd\u7a33\u5b9a\u7684\u6c34\u51dd\u80f6\u3002\u901a\u8fc7\u5c06\u5e26\u6b63\u7535\u8377\u7684EPL\u548c\u7eb3\u7c73\u5200\u72b6MnO<sub>2<\/sub>\u7eb3\u7c73\u7247\u534f\u540c\u7ed3\u5408\uff0cFEMI\u6c34\u51dd\u80f6\u5728\u4f53\u5916\u548c\u4f53\u5185\u5bf9MDR\u7ec6\u83cc\u90fd\u8868\u73b0\u51fa\u4e86\u975e\u51e1\u7684\u6297\u83cc\u80fd\u529b\u3002\u6b64\u5916\uff0cFEMI\u6c34\u51dd\u80f6\u5728\u5c0f\u9f20\u809d\u635f\u4f24\u6a21\u578b\u4e2d\u4e5f\u8868\u73b0\u51fa\u826f\u597d\u7684\u6b62\u8840\u6548\u679c\u3002\u5728\u7cd6\u5c3f\u75c5\u521b\u9762\u4e0d\u540c\u7684\u9178\u6027\u548c\u6c27\u5316\u6027\u5fae\u73af\u5883\u4e0b\uff0cFEMI\u6c34\u51dd\u80f6\u901a\u8fc7\u5c06\u5185\u6e90\u6027H<sub>2<\/sub>O<sub>2<\/sub>\u8f6c\u5316\u4e3aO<sub>2<\/sub>\uff0c\u540c\u65f6\u91ca\u653e\u80f0\u5c9b\u7d20\u6765\u8c03\u8282\u8840\u7cd6\u6c34\u5e73\uff0c\u4ece\u800c\u6709\u6548\u7f13\u89e3\u6c27\u5316\u5e94\u6fc0\u3002FEMI\u6c34\u51dd\u80f6\u5c06\u6e05\u9664\u591a\u836f\u8010\u836f\u83cc\u3001\u964d\u4f4e\u9ad8\u8840\u7cd6\u3001\u6539\u5584\u6c27\u5316\u5e94\u6fc0\u548c\u6301\u7eed\u4ea7\u6c27\u6574\u5408\u5728\u4e00\u4e2a\u5e73\u53f0\u4e0a\uff0c\u534f\u540c\u51cf\u5c11\u708e\u75c7\u53cd\u5e94\u3001\u523a\u6fc0\u8840\u7ba1\u751f\u6210\u3001\u52a0\u901f\u7ec6\u80de\u589e\u6b96\u3001\u4fc3\u8fdb\u8089\u82bd\u7ec4\u7ec7\u5f62\u6210\u548cECM\u6c89\u79ef\uff0c\u5728\u4fc3\u8fdb\u7cd6\u5c3f\u75c5\u76ae\u80a4\u91cd\u5efa\u65b9\u9762\u5177\u6709\u91cd\u8981\u7684\u5e94\u7528\u524d\u666f\u3002\u636e\u62a5\u9053\uff0c\u8fd9\u662f\u9996\u6b21\u901a\u8fc7\u5168\u9762\u6784\u5efa\u5177\u6709\u6307\u5bfc\u610f\u4e49\u7684\u76ae\u80a4\u5fae\u73af\u5883\uff0c\u6784\u5efa\u591a\u529f\u80fd\u6c34\u51dd\u80f6\u4fc3\u8fdb\u591a\u836f\u8010\u836f\u7cd6\u5c3f\u75c5\u521b\u9762\u6108\u5408\u7684\u7814\u7a76\u3002\u603b\u4e4b\uff0cFEMI\u6c34\u51dd\u80f6\u663e\u793a\u4e86\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u7b56\u7565\uff0c\u4ee5\u518d\u751f\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u5e7f\u6cdb\u53d7\u635f\u7ec4\u7ec7\uff0c\u8fd9\u4e9b\u7ec4\u7ec7\u906d\u53d7\u7ec6\u83cc\u4fb5\u88ad\u548c\u9ad8\u5ea6\u6c27\u5316\u75c5\u53d8\u7684\u5fae\u73af\u5883\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.nanolett.0c01371\">Nanoenzyme-Reinforced Injectable Hydrogel for Healing Diabetic Wounds Infected with Multidrug Resistant Bacteria<\/a> (<em>Nano Lett<\/em>., <strong>2020<\/strong>, DOI: 10.1021\/acs.nanolett.0c01371)<\/p>\n<p><strong>\u8bfe\u9898\u7ec4\u7b80\u4ecb\uff1a<\/strong><\/p>\n<p>\u5f20\u79cb\u79b9\uff0c\u201c\u957f\u6c5f\u5b66\u8005\u201d\u7279\u8058\u6559\u6388\uff0c\u535a\u58eb\u751f\u5bfc\u5e08\uff0c\u897f\u5317\u5de5\u4e1a\u5927\u5b66\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\u6240\u957f\uff0c\u4e2d\u56fd\u5316\u5b66\u4f1a\u4f1a\u5458\uff0c\u9655\u897f\u7701\u5316\u5b66\u4f1a\u7406\u4e8b\uff0c\u4e2d\u56fd\u6750\u6599\u7814\u7a76\u5b66\u4f1a\u9ad8\u5206\u5b50\u6750\u6599\u4e0e\u5de5\u7a0b\u5206\u4f1a\u59d4\u5458\uff0c\u9655\u897f\u7701\u73af\u5883\u5b66\u4f1a\u7406\u4e8b\uff0c\u4e2d\u56fd\u9897\u7c92\u5b66\u4f1a\u7406\u4e8b\u7b49\u3002\u300a\u9ad8\u5206\u5b50\u6750\u6599\u300b\u3001\u300a\u5316\u5b66\u5de5\u7a0b\u300b\u3001\u300a\u7c98\u63a5\u300b\u7b49\u671f\u520a\u7f16\u59d4\u3002\u5f20\u79cb\u79b9\u6559\u6388\u66fe\u83b7\u5168\u56fd\u5dfe\u5e3c\u5efa\u529f\u6807\u5175\u3001\u6559\u80b2\u90e8\u65b0\u4e16\u7eaa\u4f18\u79c0\u4eba\u624d\u5956\u52b1\u8ba1\u5212\u3001\u9655\u897f\u7701\u79d1\u6280\u5956\u4e00\u7b49\u5956\u3001\u4e8c\u7b49\u5956\u4e09\u9879\u3001\u9655\u897f\u7701\u9752\u5e74\u79d1\u6280\u5956\u3001\u6559\u80b2\u90e8\u970d\u82f1\u4e1c\u9752\u5e74\u6559\u6388\u6559\u5b66\u5956\u7b49\u5956\u52b1\u3002\u4e3b\u8981\u7814\u7a76\u65b9\u5411\u4e3a\u591a\u5b54\u805a\u5408\u7269\u6750\u6599\u3001\u5fae\u7eb3\u7c73\u6709\u673a\/\u65e0\u673a\u6750\u6599\u6742\u5316\u6750\u6599\uff0c\u4eff\u751f\u667a\u80fd\u4e0e\u529f\u80fd\u6027\u9ad8\u5206\u5b50\u6750\u6599\u7b49\u3002\u7814\u5236\u4e86\u591a\u79cd\u9ad8\u6548\u5206\u79bb\u7684\u591a\u5b54\u6709\u673a\u6750\u6599\u3001\u5177\u6709\u7535\u78c1\u54cd\u5e94\u6027\u7684\u5fae\u7eb3\u7c73\u9ad8\u5206\u5b50\u6742\u5316\u6750\u6599\u3001\u81ea\u4fee\u590d\u9ad8\u5206\u5b50\u590d\u5408\u6750\u6599\u3002\u8bfe\u9898\u7ec4\u8fc4\u4eca\u5df2\u5728J.Mater.Chem. A, Appl. Catal. 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