{"id":207855,"date":"2020-08-23T06:50:32","date_gmt":"2020-08-22T22:50:32","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=207855"},"modified":"2020-08-22T17:50:51","modified_gmt":"2020-08-22T09:50:51","slug":"%e5%94%90%e6%9c%ac%e5%bf%a0%e9%99%a2%e5%a3%ab%e5%9b%a2%e9%98%9fadv-mater-%ef%bc%9a%e8%81%9a%e9%9b%86%e8%af%b1%e5%af%bc%e5%8f%91%e5%85%89%e6%9d%90%e6%96%99%e4%b8%8e%e4%ba%8c%e7%bb%b4%e9%bb%91%e7%a3%b7","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=207855","title":{"rendered":"\u5510\u672c\u5fe0\u9662\u58eb\u56e2\u961fAdv. Mater.\uff1a\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\u6750\u6599\u4e0e\u4e8c\u7ef4\u9ed1\u78f7\u7eb3\u7c73\u7247\u7ed3\u5408\u5b9e\u73b0\u80bf\u7624\u7684\u591a\u6a21\u6001\u8bca\u7597"},"content":{"rendered":"

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\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/b><\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u5510\u672c\u5fe0\u9662\u58eb\u56e2\u961f<\/b><\/strong>\u9996\u6b21\u8bbe\u8ba1\u4e86\u4e00\u79cd\u7ed3\u5408AIE PS\u548cBP\u7eb3\u7c73\u7247\u7684\u65b0\u578b\u591a\u529f\u80fd\u6cbb\u7597\u8bca\u65ad\u7eb3\u7c73\u5e73\u53f0\u3002\u901a\u8fc7\u9759\u7535\u4f5c\u7528\u5728BP\u7eb3\u7c73\u7247\u8868\u9762\u6d82\u4e0a\u4e00\u5c42\u6c34\u6eb6\u6027\u5e26\u6b63\u7535\u8377\u7684AIE PS\uff08NH2<\/sub>-PEG-TTPy\uff09\uff0c\u4ece\u800c\u5236\u5907\u51fa\u4e86\u7eb3\u7c73\u5e73\u53f0BP@PEG-TTPy\u3002\u8fd9\u4e00\u7b56\u7565\u4e0d\u4ec5\u63d0\u9ad8\u4e86BP\u7eb3\u7c73\u7247\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u751f\u7406\u7a33\u5b9a\u6027\uff0c\u800c\u4e14\u8d4b\u4e88\u4e86\u8be5\u6cbb\u7597\u6027\u7eb3\u7c73\u5e73\u53f0\u5728\u8fd1\u7ea2\u5916\u533a\u57df\u7684\u5f3a\u8367\u5149\u53d1\u5c04\u548cPDT\u80fd\u529b\u3002\u4f53\u5916\u548c\u4f53\u5185\u8bc4\u4f30\u5747\u663e\u793a\uff0c\u591a\u529f\u80fdBP@PEG-TTPy\u5728\u8fd1\u7ea2\u5916FLI-PTI\u53cc\u6210\u50cf\u5f15\u5bfc\u7684PDT – PTT\u534f\u540c\u5149\u7597\u7684\u764c\u75c7\u6cbb\u7597\u5b66\u4e2d\u8868\u73b0\u826f\u597d\u3002\u8be5\u6210\u679c\u4ee5\u9898\u4e3a\u201c<\/b><\/strong>Aggregation-Induced Emission Luminogens Married to 2D Black Phosphorus Nanosheets for Highly Efficient Multimodal Theranostics<\/b><\/strong>\u201d<\/b><\/strong>\u53d1\u8868\u5728\u4e86Adv. Mater.<\/b><\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/b><\/strong><\/p>\n

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A\uff09\u6837\u54c1\u7684Zeta\u7535\u4f4d\u3002<\/p>\n

B-E\uff09BP@PEG-TTPy\u7684XPS\u5149\u8c31\uff1a\u603b\u8c31\u3001P 2p\u3001C 1s\u548cN 1s\u5149\u8c31\u3002<\/p>\n

F-H\uff09BP@PEG-TTPy\u7684F\uff09TEM\u3001G\uff09AFM\u56fe\u50cf\u548cH\uff09\u62c9\u66fc\u5149\u8c31\u3002<\/p>\n

I\uff09\u6837\u54c1\u7684\u7d2b\u5916-\u53ef\u89c1-\u8fd1\u7ea2\u5916\u5149\u8c31\u3002\uff08I\uff09\u4e2d\u7684\u63d2\u56fe\uff1ai-iii\uff09\u4ee5\u4e0b\u7167\u7247\uff1ai\uff09BP\u7eb3\u7c73\u7247\uff0cii\uff09NH2<\/sub>-PEG-TTPy\u548ciii\uff09BP@PEG-TTPy\u3002<\/p>\n

J\uff09\u6837\u54c1\u7684\u8367\u5149\u5149\u8c31\u3002\u6d53\u5ea6\uff1aNH2<\/sub>-PEG-TTPy\uff084 mg mL-1<\/sup>\uff09\uff0cBP@PEG-TTPy-1\uff0850\u03bcgmL-1 BP NSs\uff0c4 mg mL-1 NH2<\/sub>-PEG-TTPy\uff09\uff0cBP@PEG-TTPy \uff08100 \u00b5g mL-1<\/sup>\u7684BP\u7eb3\u7c73\u7247\uff0c4 mg mL-1<\/sup>\u7684NH2<\/sub>-PEG-TTPy\uff09\u548cBP\u7eb3\u7c73\u7247\uff08100 \u00b5g mL-1<\/sup>\uff09\u3002\u6fc0\u53d1\u6ce2\u957f\uff1a488nm\u3002<\/p>\n

K\uff09\u5728808 nm NIR\u6fc0\u5149\u7167\u5c04\u4e0b\uff0c\u4e0d\u540cBP\u6d53\u5ea6\u4e0bPBS\u4e2dBP@PEG-TTPy\u7684\u5149\u70ed\u52a0\u70ed\u66f2\u7ebf\u3002<\/p>\n

L\uff09\u7528808 nm NIR\u6fc0\u5149\u5728\u4e94\u4e2a\u5f00\/\u5173\u7167\u5c04\u5468\u671f\u4e2dBP@PEG-TTPy\u5728PBS\u4e2d\u7684\u5149\u70ed\u7a33\u5b9a\u6027\u3002<\/p>\n

\u56fe<\/b><\/strong>3<\/b><\/strong>\u00a0<\/b><\/strong>4T1\u7ec6\u80de\u4e2d\u7684\u7ec6\u80de\u5185ROS\u4ea7\u751f\"\"<\/p>\n

A\uff09\u4ee5DCFH-DA\u4f5c\u4e3a\u6307\u793a\u5242\uff0c\u5728\u767d\u5149\u548c808 nm NIR\u6fc0\u5149\u7167\u5c04\u4e0b\u4ea7\u751fROS\u3002<\/p>\n

B\uff09DCFH-DA\u68c0\u6d4b4T1\u7ec6\u80de\u4e2d\u7684\u7ec6\u80de\u5185ROS\u4ea7\u751f\u3002\u6838\u7528Hoechst 33342\u67d3\u8272\u3002<\/p>\n

C\uff09\u5728\u6709\u6216\u6ca1\u6709\u767d\u5149\uff0824 mW cm-2<\/sup>\uff09\u548c808808 nm\u8fd1\u7ea2\u5916\u6fc0\u5149\uff081 W cm-2<\/sup>\uff09\u7167\u5c0410\u5206\u949f\u60c5\u51b5\u4e0b\uff0c\u5728\u4e0d\u540c\u7684BP\u548cNH2<\/sub>-PEG-TTPy\u5904\u74064T1\u7ec6\u80de\u540e\u7684\u76f8\u5bf9\u5b58\u6d3b\u7387\u3002* P <0.05\uff0c** P <0.01\u548c*** P <0.001\u3002<\/p>\n

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E\uff0cF\uff09\u5728\u7528BP@PEG-TTPy\u548cMitoTracker Green\u914d\u8272\u540e\uff0c\u767d\u5149\u548c808 nm\u8fd1\u7ea2\u5916\u6fc0\u5149\u7167\u5c04\u524d\uff08E\uff09\u548c\uff08F\uff095\u5206\u949f\u540e\u7ebf\u7c92\u4f53\u5f62\u6001\u7684\u53d8\u5316\u3002<\/p>\n

G\uff09BP@PEG-TTPy\u7684\u7ec6\u80de\u5185\u9012\u9001\u9014\u5f84\u548c\u534f\u540c\u6297\u80bf\u7624\u6cbb\u7597\u3002<\/p>\n

\u56fe<\/b><\/strong>4<\/b><\/strong>\u00a0<\/b><\/strong>\u4f53\u5185\u6210\u50cf\u548c\u6297\u80bf\u7624\u4f5c\u7528\u76844T1-\u80bf\u7624\u5c0f\u9f20<\/b><\/strong>\"\"<\/p>\n

A\uff09\u6ce8\u5c04BP@PEG-TTPy\u540e\u7684\u5c0f\u9f20\u5ef6\u65f6\u8fd1\u7ea2\u5916\u8367\u5149\u68c0\u6d4b\u3002<\/p>\n

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\u3010<\/b><\/strong>\u5c0f\u7ed3<\/b><\/strong>\u3011<\/b><\/strong><\/p>\n

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\u6587\u732e\u94fe\u63a5\uff1a<\/b><\/strong>Aggregation-Induced Emission Luminogens Married to 2D Black Phosphorus Nanosheets for Highly Efficient Multimodal Theranostics<\/u><\/a>\uff08Adv. Mater.\uff0c2020\uff0cDOI:10.1002\/adma.202003382\uff09<\/p>\n

\u672c\u6587\u7531\u6728\u6587\u97ec<\/b><\/strong>\u7ffb\u8bd1\u7f16\u8f91\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com<\/u><\/a>\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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