{"id":212342,"date":"2020-11-06T06:31:36","date_gmt":"2020-11-05T22:31:36","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=212342"},"modified":"2020-11-05T20:31:46","modified_gmt":"2020-11-05T12:31:46","slug":"%e5%8d%97%e6%b4%8b%e7%90%86%e5%b7%a5angew%ef%bc%9a%e7%94%a8%e4%ba%8e%e6%b7%b1%e5%b1%82%e6%b4%bb%e4%bd%93%e6%88%90%e5%83%8f%e7%9a%84%e9%95%bf%e6%b3%a2%e9%95%bf%e8%bf%91%e7%ba%a2%e5%a4%96%e5%8c%96","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=212342","title":{"rendered":"\u5357\u6d0b\u7406\u5de5Angew\uff1a\u7528\u4e8e\u6df1\u5c42\u6d3b\u4f53\u6210\u50cf\u7684\u957f\u6ce2\u957f\u8fd1\u7ea2\u5916\u5316\u5b66\u53d1\u5149\u63a2\u9488"},"content":{"rendered":"

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\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

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\"\"<\/p>\n

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\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\u56fe\u4e09\u3001\u9176\u54cd\u5e94\u6210\u50cf<\/strong><\/p>\n

\"\"<\/p>\n

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\"\"<\/p>\n

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\u3010\u7ed3\u8bba\u5c55\u671b\u3011<\/strong><\/p>\n

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\u6587\u732e\u94fe\u63a5\uff1aMolecular Chemiluminescent Probes with a Record Long Near-infrared Turn-on Wavelength for In vivo Imaging<\/a> (Angew. Chem. Int. Ed<\/em>, 2020<\/strong>, DOI: 10.1002\/anie.202013531)<\/p>\n

\u56e2\u961f\u7b80\u4ecb\uff1a<\/strong><\/p>\n

\u6d66\u4f83\u88d4\uff0c\u73b0\u4efb\u65b0\u52a0\u5761\u5357\u6d0b\u7406\u5de5\u5927\u5b66\u5316\u5b66\u4e0e\u751f\u7269\u533b\u5b66\u5de5\u7a0b\u5b66\u9662\u526f\u6559\u6388\uff1b2011\u5e74\u4e8e\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u83b7\u5f97\u535a\u58eb\u5b66\u4f4d\uff0c\u540c\u5e74\u4f5c\u4e3a\u535a\u58eb\u540e\u52a0\u5165\u65af\u5766\u798f\u5927\u5b66\u4ece\u4e8b\u5206\u5b50\u5f71\u50cf\u5b66\u7814\u7a76\uff0c2015\u5e746\u6708\u4ee5\u526f\u6559\u6388\u53d7\u8058\u4e8e\u5357\u6d0b\u7406\u5de5\u5927\u5b66\u3002<\/p>\n

\u8fd1\u5e74\u6765\uff0c\u6d66\u4f83\u88d4\u6559\u6388\u8bfe\u9898\u7ec4\u4e3b\u8981\u63a2\u7d22\u6709\u673a\u6750\u6599\u5728\u751f\u7269\u533b\u5b66\u5149\u5b50\u5b66\u4e2d\u5e94\u7528\u3002\u76ee\u524d\u4e3b\u8981(i)\u9488\u5bf9\u4e34\u5e8a\u9700\u6c42\u5f00\u53d1\u667a\u80fd\u54cd\u5e94\u578b\u6d3b\u4f53\u8367\u5149\u3001\u81ea\u53d1\u5149\u53ca\u5149\u58f0\u6210\u50cf\u5206\u5b50\u63a2\u9488\u7528\u4e8e\u65e9\u671f\u75be\u75c5\u8bca\u65ad;(ii) \u9488\u5bf9\u57fa\u7840\u751f\u7269\u533b\u5b66\u5f00\u53d1\u57fa\u4e8e\u534a\u5bfc\u4f53\u805a\u5408\u7269(SPN\uff1asemiconducting polymer nanoparticles)\u7684\u7eb3\u7c73\u5149\u5b50\u8f6c\u6362\u5668\u7528\u4e8e\u5728\u5206\u5b50\u5c42\u9762\u8c03\u63a7\u5e76\u4e86\u89e3\u751f\u7269\u8fc7\u7a0b\uff1b(iii)\u7814\u7a76\u6709\u673a\u5149\u5b66\u6750\u6599\u5728\u80bf\u7624\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u3002\u76ee\u524d\uff0c\u8be5\u8bfe\u9898\u7ec4\u5df2\u5728\u764c\u75c7\u8bca\u7597\u3001\u76ae\u80a4\u75c5\u68c0\u6d4b\u4e0e\u836f\u7269\u6bd2\u6027\u7b5b\u9009\u4e2d\u53d6\u5f97\u521d\u6b65\u8fdb\u5c55\u3002\u4f8b\u5982\uff0c\u57282017\u5e74\u8be5\u8bfe\u9898\u7ec4\u9996\u6b21\u5f00\u521b\u4e86\u57fa\u4e8e\u53ef\u964d\u89e3\u6709\u673a\u9ad8\u5206\u5b50\u7eb3\u7c73\u9897\u7c92\u7684\u5206\u5b50\u4f59\u8f89\u6210\u50cf(MAI: molecular afterglow imaging)\uff0c\u5e76\u63a2\u7d22\u4e86\u5176\u5728\u75be\u75c5\u7684\u65e9\u671f\u8bca\u65ad\u548c\u6cbb\u7597\u65b9\u9762\u7684\u6f5c\u5728\u5e94\u7528\u3002\u8be5\u7814\u7a76\u6210\u679c\u53d1\u8868\u4e8e\u56fd\u9645\u9876\u7ea7\u671f\u520aNature Biotechnology\u3002\u57282019\u5e74\u8be5\u8bfe\u9898\u7ec4\u8bbe\u8ba1\u4e86\u4e00\u79cd\u5177\u6709\u9ad8\u6548\u7684\u80be\u6e05\u9664\u6548\u7387\u7684\u5206\u5b50\u80be\u810f\u63a2\u9488(MRPs: molecular renal probes)\u7528\u4e8e\u5bf9\u836f\u7269\u6027\u6025\u6027\u80be\u635f\u4f24(AKI: acute kidney injury)\u7684\u4f53\u5185\u5149\u5b66\u6210\u50cf\u3002\u8be5\u63a2\u9488\u7684\u8fd1\u7ea2\u5916\u8367\u5149\u6216\u8005\u5316\u5b66\u53d1\u5149\u4fe1\u53f7\u53ef\u4ee5\u88abAKI\u7684\u524d\u671f\u751f\u7269\u6807\u8bb0\u7269\u7279\u5f02\u6027\u5730\u6fc0\u6d3b\uff0c\u4f7f\u5f97\u8be5\u63a2\u9488\u53ef\u4ee5\u5bf9\u5b9e\u9a8c\u5c0f\u9f20\u80be\u810f\u5185\u591a\u4e2a\u5206\u5b50\u4e8b\u4ef6\u8fdb\u884c\u7eb5\u5411\u6210\u50cf\u3002\u8be5\u7814\u7a76\u6210\u679c\u53d1\u8868\u4e8e\u56fd\u9645\u9876\u7ea7\u671f\u520aNature Materials\u3002\u53e6\u5916\uff0c\u91c7\u7528\u8fd1\u7ea2\u5916\u8367\u5149\u548c\u5149\u58f0\u7b49\u6210\u50cf\u6280\u672f\uff0c\u8be5\u7ec4\u5b9e\u73b0\u4e86\u76ae\u80a4\u75c5\u3001\u809d\u635f\u4f24\u4ee5\u53ca\u80bf\u7624\u7b49\u75be\u75c5\u53d1\u5c55\u8fc7\u7a0b\u4e2d\u76f8\u5173\u751f\u7269\u6807\u8bb0\u7269\u7684\u6d3b\u4f53\u68c0\u6d4b\uff0c\u4e3a\u75be\u75c5\u7684\u65e9\u671f\u8bca\u65ad\u63d0\u4f9b\u4e86\u6709\u7528\u4fe1\u606f\u3002\u8be5\u56e2\u961f\u7814\u7a76\u65b9\u5411\u4e5f\u6d89\u53ca\u667a\u80fd\u54cd\u5e94\u578b\u7eb3\u7c73\u533b\u836f\uff0c\u5149\u70ed\u8c03\u63a7\u79bb\u5b50\u901a\u9053\u3001\u57fa\u56e0\u8868\u8fbe\u548c\u86cb\u767d\u6d3b\u6027\u7b49\u76f8\u5173\u7814\u7a76\u3002\u81ea2015\u5e746\u6708\u6210\u7acb\u81f3\u4eca\uff0c\u8be5\u56e2\u961f\u5df2\u5728\u56fd\u9645\u4e3b\u6d41\u671f\u520a\u4e0a\u53d1\u8868\u9ad8\u6c34\u5e73\u6587\u7ae080\u591a\u7bc7\uff08\u5305\u62ecNature Materials, Nature Biotechnology, Nature Communications, Chemical Society Reviews, Accounts of Chemical Research, Journal of the American Chemical Society, Angewandte Chemie International Edition, Advanced Materials, Nano Letters, ACS Nano\u7b49\uff09\u3002\u81f3\u4eca\uff0c\u6d66\u4f83\u88d4\u6559\u6388\u7d2f\u8ba1\u53d1\u8868\u9ad8\u6863\u6b21\u6587\u7ae0160\u591a\u7bc7\uff0cSCI H-index = 65\u3002\u76ee\u524d\uff0c\u6d66\u4f83\u88d4\u535a\u58eb\u62c5\u4efbACS Applied Polymer Materials \u548cBiomaterials Research\u526f\u4e3b\u7f16\uff0cNano Research\u671f\u520aYoung Star\u4e3b\u7f16\uff0cAdvanced Functional Materials, Small, Bioconjugate Chemistry, ACS Applied Bio Materials, Advanced Biosystems\u548cChemNanoMat\u7b49\u671f\u520a\u7f16\u59d4\u3002<\/p>\n

\u8bfe\u9898\u7ec4\u4e3b\u9875\uff1a<\/strong>https:\/\/personal.ntu.edu.sg\/kypu\/index.html<\/a><\/p>\n

\u8fd1\u671f\u4ee3\u8868\u6027\u5de5\u4f5c\uff1a<\/strong><\/p>\n

    \n
  1. Cheng Xu, Kanyi Pu. Second near-infrared photothermal materials for combinational nanotheranostics. Chemical Society Reviews<\/em>, 2020, 49, accepted.<\/li>\n
  2. Qianxi Dang, Yuyan Jiang, Jinfeng Wang, Jiaqiang Wang, Qunhua Zhang, Mingkang Zhang, Simeng Luo, Yujun Xie, Kanyi Pu, Qianqian Li, Zhen Li. Room-temperature phosphorescence resonance energy transfer for construction of near-infrared afterglow imaging agents. Advanced Materials<\/em>, 2020, 32, DOI: 10.1002\/adma.202006752.<\/li>\n
  3. Xu Zhen, Kanyi Pu, Xiqun Jiang. Photoacoustic imaging and photothermal therapy of semiconducting polymer nanoparticles: signal amplification and second near-infrared construction. Small<\/em>, 2020.<\/li>\n
  4. Jingsheng Huang, Jiaguo Huang, Penghui Cheng, Yuyan Jiang, Kanyi Pu. Near-infrared chemiluminescent reporters for in vivo imaging of reactive oxygen and nitrogen species in kidneys. Advanced Functional Materials<\/em>,<\/span> 2020, 30, 2003628\u00a0.<\/li>\n<\/ol>\n

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