{"id":224266,"date":"2021-07-06T06:30:02","date_gmt":"2021-07-05T22:30:02","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=224266"},"modified":"2021-07-05T14:36:01","modified_gmt":"2021-07-05T06:36:01","slug":"%e5%8d%8e%e4%b8%ad%e7%a7%91%e6%8a%80%e5%a4%a7%e5%ad%a6%e8%82%96%e5%85%88%e9%87%91%e5%9b%a2%e9%98%9facs-nano%ef%bc%9a%e7%b2%be%e7%bb%86%e8%b0%83%e6%8e%a7dna%e9%93%be%e7%bd%ae%e6%8d%a2%e5%8f%8d","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=224266","title":{"rendered":"\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u8096\u5148\u91d1\u56e2\u961fACS\u00a0Nano\uff1a\u7cbe\u7ec6\u8c03\u63a7DNA\u94fe\u7f6e\u6362\u53cd\u5e94\u548c\u6784\u5efa\u590d\u6742DNA\u7eb3\u7c73\u88c5\u7f6e\u7684\u591a\u529f\u80fdClip\u5e8f\u5217"},"content":{"rendered":"<p>DNA\u7eb3\u7c73\u6280\u672f\u662f\u7eb3\u7c73\u6280\u672f\u7684\u4e00\u4e2a\u91cd\u8981\u5206\u652f\uff0c\u57fa\u4e8e\u78b1\u57fa\u4e92\u8865\u914d\u5bf9\u7684\u9ad8\u7279\u5f02\u6027\u548c\u53ef\u7f16\u7a0b\u6027\uff0cDNA\u53ef\u4ee5\u88ab\u8bbe\u8ba1\u6210\u5177\u6709\u7279\u6b8a\u529f\u80fd\u7684\u7eb3\u7c73\u88c5\u7f6e\uff0c\u4f8b\u5982DNA 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walker\u7684\u884c\u8d70\u8def\u5f84<\/p>\n<p>\u5229\u7528Clip\u591a\u529f\u80fd\u7684\u4f18\u52bf\uff0c\u8bfe\u9898\u7ec4\u8fdb\u4e00\u6b65\u6784\u5efa\u4e86\u57fa\u4e8eClip\u5143\u4ef6\u7684DNA\u6b65\u884c\u673a\uff08DNA walker\uff09\uff0c\u5b9e\u73b0\u53ef\u63a7\u884c\u8d70\u548c\u53ef\u7f16\u7a0b\u8def\u5f84\u7684\u72ec\u7279\u529f\u80fd\u3002\u6b64\u5916\uff0c\u8bfe\u9898\u7ec4\u8fd8\u6784\u5efa\u4e86\u57fa\u4e8eClip\u5143\u4ef6\u7684 AND\/OR \u903b\u8f91\u95e8\u5e76\u96c6\u6210\u8fd9\u4e9b\u903b\u8f91\u95e8\uff0c\u5b9e\u73b0\u590d\u6742\u7684\u903b\u8f91\u7535\u8def\u3002\u67e5\u9605\u6587\u732e\u53ef\u77e5\uff0c\u8bfe\u9898\u7ec4\u6784\u5efa\u7684 DNA \u903b\u8f91\u7535\u8def\u662f\u7b2c\u4e00\u4e2a\u771f\u6b63\u610f\u4e49\u4e0a\u53ef\u4ee5\u91cd\u590d\u8ba1\u7b97\u3001\u5904\u7406\u4e0d\u540c\u8f93\u5165\u4fe1\u53f7\u7684 DNA \u7535\u8def\u3002<\/p>\n<p>\u8bfe\u9898\u7ec4\u5f00\u53d1\u7684\u65b0\u578bDNA\u94fe\u7f6e\u6362\u53cd\u5e94\u8c03\u63a7\u5143\u4ef6\u201cClip\u201d\u6210\u529f\u5730\u5bf9\u5404\u79cdDNA\u7eb3\u7c73\u673a\u5668\u8fdb\u884c\u517c\u5bb9\uff0c\u5b9e\u73b0\u591a\u79cd\u7075\u6d3b\u4e14\u590d\u6742\u7684\u529f\u80fd\uff0c\u53ef\u4ee5\u6781\u5927\u62d3\u5c55DNA\u7eb3\u7c73\u673a\u5668\u5728\u6838\u9178\u7814\u7a76\u548c\u533b\u5b66\u9886\u57df\u7684\u5e94\u7528\u3002<\/p>\n<p>\u8fd9\u4e00\u6210\u679c\u8fd1\u671f\u53d1\u8868\u5728\u300aACS Nano\u300b\u4e0a\uff0c\u6587\u7ae0\u7b2c\u4e00\u4f5c\u8005\u662f\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u5b66\u751f\u5218\u7406\u6743\uff0c\u80e1\u6e05\u6f2a\u548c\u5f20\u6e29\u51ef\u3002\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u8096\u5148\u91d1\u6559\u6388\u662f\u672c\u6587\u7684\u552f\u4e00\u901a\u8baf\u4f5c\u8005\u3002<\/p>\n<p>\u8096\u5148\u91d1\u6559\u6388\u8bfe\u9898\u7ec4\u81ea2016\u5e74\u6210\u7acb\u4ee5\u6765\uff0c\u5728\u751f\u7269\u533b\u5b66\u4ea4\u53c9\u9886\u57df\u5df2\u53d1\u8868\u591a\u7bc7\u8bba\u6587\uff0c\u5efa\u7acb\u4e86\u575a\u5b9e\u4e30\u539a\u7684\u7406\u8bba\u548c\u6280\u672f\u57fa\u7840\u3002\u8096\u5148\u91d1\u6559\u6388\u672c\u3001\u7855\u3001\u535a\u5747\u6bd5\u4e1a\u4e8e\u5317\u4eac\u5927\u5b66\uff0c\u76ee\u524d\u4e3b\u6301\u4e86\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9752\u5e74\u9879\u76ee\u3001\u9762\u4e0a\u9879\u76ee\uff0c\u6e56\u5317\u7701\u91cd\u5927\u79d1\u6280\u653b\u5173\u5b50\u8bfe\u9898\u7b4910\u4f59\u4e2a\u9879\u76ee\uff0c\u83b7\u5f97\u4e86\u4e2d\u56fd\u65b0\u9510\u79d1\u6280\u4eba\u7269\u5353\u8d8a\u5f71\u54cd\u5956\u3001\u6b66\u6c49\u5e02\u6668\u5149\u8ba1\u5212\u3001\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u5b66\u672f\u65b0\u4eba\u5956\u7b49\u4eba\u624d\u5956\u52b1\u3002\u5165\u804c\u4e94\u5e74\u6765\uff0c\u53d1\u8868\u7b2c\u4e00\u4f5c\u8005\/\u901a\u8baf\u4f5c\u8005\u8bba\u658730\u4f59\u7bc7\uff0c\u5305\u62ecNature Communications\u3001Nucleic Acids Research\u7b49\uff0c\u603b\u5f71\u54cd\u56e0\u5b50\u8d85\u8fc7180\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-224269\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2021\/07\/\u56fe\u72473.png\" alt=\"\" width=\"600\" height=\"655\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2021\/07\/\u56fe\u72473.png 600w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2021\/07\/\u56fe\u72473-275x300.png 275w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u56fe\u4e09\u3001\u57fa\u4e8eClip\u7684\u53ef\u91cd\u590d\u8fd0\u7b97\u7684DNA\u903b\u8f91\u7535\u8def<\/p>\n<p>\u8bba\u6587\u4fe1\u606f\uff1a<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.1c01763\"><u>https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.1c01763#<\/u><\/a>\u00a0<\/p>\n<p>Liquan Liu, Qingyi Hu, Wenkai Zhang, Wenhao Li, Wei Zhang, Zhihao Ming, Longjie Li, Na Chen, Hongbo Wang, and Xianjin Xiao*. Multifunctional Clip Strand for the Regulation of DNA Strand Displacement and Construction of Complex DNA Nanodevices. <strong><em><b><i>ACS N<\/i><\/b><\/em><\/strong><strong><em><b><i>ano<\/i><\/b><\/em><\/strong><strong><em><b><i>, <\/i><\/b><\/em><\/strong>2021, 10.1021\/acsnano.1c01763.<\/p>\n<p>\u672c\u6587\u7531\u4f5c\u8005\u6295\u7a3f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DNA\u7eb3\u7c73\u6280\u672f\u662f\u7eb3\u7c73\u6280\u672f\u7684\u4e00\u4e2a\u91cd\u8981\u5206\u652f\uff0c\u57fa\u4e8e\u78b1\u57fa\u4e92\u8865\u914d\u5bf9\u7684\u9ad8\u7279\u5f02\u6027\u548c\u53ef\u7f16\u7a0b\u6027\uff0cDNA\u53ef\u4ee5\u88ab\u8bbe\u8ba1\u6210\u5177\u6709\u7279\u6b8a\u529f\u80fd\u7684\u7eb3\u7c73\u88c5\u7f6e\uff0c\u4f8b\u5982DNA \u7535\u8def\u548cDNA\u673a\u5668\u4eba\u3002\u76ee\u524d\uff0c\u8fd9&#8230;<\/p>\n","protected":false},"author":11454,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-224266","post","type-post","status-publish","format-standard","hentry","category-keji"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/224266"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/11454"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=224266"}],"version-history":[{"count":1,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/224266\/revisions"}],"predecessor-version":[{"id":224270,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/224266\/revisions\/224270"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=224266"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=224266"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=224266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}