{"id":237766,"date":"2022-05-29T06:45:04","date_gmt":"2022-05-28T22:45:04","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=237766"},"modified":"2022-05-28T21:13:11","modified_gmt":"2022-05-28T13:13:11","slug":"%e5%b7%b2%e5%ae%a1%e7%94%b5%e5%82%ac%e5%8c%96%e4%b8%ad%e9%97%b4%e6%b0%a2%e5%8c%96%e7%89%a9%e5%8a%a9%e5%8a%9b%e7%94%9f%e7%89%a9%e5%82%ac%e5%8c%96nadh%e5%86%8d%e7%94%9f","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=237766","title":{"rendered":"\u7535\u50ac\u5316\u4e2d\u95f4\u6c22\u5316\u7269\u52a9\u529b\u751f\u7269\u50ac\u5316NADH\u518d\u751f"},"content":{"rendered":"

\u4e00\u3001\u5bfc\u8bfb<\/strong><\/p>\n

\u7edd\u5927\u591a\u6570 (90%) \u7684\u6c27\u5316\u8fd8\u539f\u9176\u4f9d\u8d56\u4e8e\u751f\u7269\u80fd\u91cf\u8f7d\u4f53\u70df\u9170\u80fa\u817a\u560c\u5464\u4e8c\u6838\u82f7\u9178 (NAD) \u53ca\u5176\u8fd8\u539f\u7684\u6c22\u5316\u5f62\u5f0f (NADH)\uff0c\u6216\u5b83\u4eec\u7684\u78f7\u9178\u5316\u5f62\u5f0f (NADP(H))\uff0c\u4f5c\u4e3a\u8f85\u52a9\u56e0\u5b50\u3002NADH\u662f\u751f\u547d\u4f53\u4e2d\u91cd\u8981\u7684\u8f85\u9176\uff0c\u662f\u751f\u547d\u4f53\u4e2d\u91cd\u8981\u7684\u6c22\u6e90\uff0c\u5bf9\u4eba\u4f53\u5185\u7684\u4e0a\u5343\u79cd\u751f\u7406\u4ee3\u8c22\u53cd\u5e94\u8d77\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u3002NADH\u662f\u4eba\u4f53\u5185\u539f\u672c\u5c31\u542b\u6709\u7684\u7269\u8d28\uff0c\u4e5f\u662f\u81ea\u7136\u754c\u552f\u4e00\u4e00\u79cd\u53ef\u4ee5\u4e0e\u4eba\u4f53\u7ec6\u80de\u5b8c\u5168\u878d\u5408\u7684\u7269\u8d28\uff0c\u968f\u7740\u4eba\u4f53\u8870\u8001\u7ec6\u80de\u6570\u91cf\u8d8a\u6765\u8d8a\u591a\uff0cNADH\u8fdb\u5165\u4eba\u4f53\u5185\u53ef\u4ee5\u5f88\u5feb\u6210\u4e3a\u7ec6\u80de\u7684\u4e00\u90e8\u5206\u8f6c\u5316\u4e3aNAD+\uff0c\u5feb\u901f\u53ca\u65f6\u4e3a\u7ec6\u80de\u63d0\u4f9b\u80fd\u91cf\uff0c\u4fee\u590d\u53d7\u635f\u75c5\u53d8\u7ec6\u80de\uff0c\u4f7f\u7ec6\u80de\u5feb\u901f\u6062\u590d\u6d3b\u529b\u3002\u80fd\u591f\u6ee1\u8db3\u4e0d\u540c\u9002\u7528\u4eba\u7fa4\u7684\u4e0d\u540c\u9700\u6c42\uff0c\u56e0\u6b64\u6025\u9700\u5f00\u53d1\u4e00\u79cd\u6210\u672c\u4f4e\u3001\u6027\u80fd\u7a33\u5b9a\u7684NADH\u518d\u751f\u6280\u672f\u3002<\/p>\n

\u4e8c\u3001\u6210\u679c\u63a0\u5f71<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u963f\u535c\u675c\u62c9\u56fd\u738b\u79d1\u6280\u5927\u5b66 (KAUST)\u7269\u7406\u79d1\u5b66\u4e0e\u5de5\u7a0b\u90e8\uff0cKAUST \u50ac\u5316\u4e2d\u5fc3\uff0c\u62a5\u9053\u4e86\u4e00\u79cd\u7535\u50ac\u5316\u4e2d\u95f4\u6c22\u5316\u7269\u52a9\u529b\u751f\u7269\u50ac\u5316NADH\u518d\u751f\u7684\u65b9\u6cd5\u3002\u60f3\u8981\u5f97\u5230\u8fd8\u539f\u5f62\u6001\u7684NADH\u9700\u8981\u907f\u514d\u5355\u7535\u5b50\u8f6c\u79fb\uff0c\u5355\u7535\u5b50\u8f6c\u79fb\u901a\u5e38\u4f1a\u5f62\u6210\u4e0d\u5177\u6709\u751f\u7269\u6d3b\u6027\u7684NAD\u4e8c\u805a\u4f53\u62161,2-\u548c1,6-\u4e8c\u6c22\u5421\u5576\u4ea7\u7269\uff0c\u60f3\u8981\u907f\u514d\u5355\u7535\u5b50\u8f6c\u79fb\u5e76\u80fd\u591f\u76f4\u63a5\u8fdb\u884c\u6c22\u5316\u7269\u8f6c\u79fb\uff0c\u9700\u8981\u5177\u6709\u5f3a\u6c22\u5316\u7269\u5f62\u6210\u80fd\u7684\u91d1\u5c5e\uff08\u4f8b\u5982\u949b\uff0c\u5df2\u88ab\u8bc1\u660e\u53ef\u4ee5\u6700\u5927\u9650\u5ea6\u51cf\u5c11\u5355\u7535\u5b50\u8f6c\u79fb\uff09\uff0c\u800c\u94bc\u548c\u949b\u4e00\u6837\uff0c\u5177\u6709\u5f88\u5927\u7684\u91d1\u5c5e\u6c22\u5316\u7269\u952e\u5f3a\u5ea6\u3002\u7531\u4e8e\u91d1\u5c5e\u94bc\u7684\u5f3a\u6c22\u7ed3\u5408\u80fd\uff0c\u53cd\u800c\u6709\u5229\u4e8e\u7c7b\u786b\u9187\u673a\u5236\u3002\u901a\u8fc7\u7535\u50ac\u5316\u53cd\u5e94\uff0c \u53ef\u4ee5\u5728\u94bc\u7684\u6d3b\u6027\u4f4d\u70b9\u4e0a\u5f62\u6210H2<\/sub>\u4e2d\u95f4\u4f53\u3002\u6b64\u5916\uff0c\u5728\u7535\u50ac\u5316\u6790\u6c22\u53cd\u5e94\uff08HER\uff09\u8fc7\u7a0b\u4e2d a-MoSx<\/sub> \u7684\u7535\u5316\u5b66\u6ef4\u5b9a\u8868\u660e\u5b58\u5728\u53cc\u7535\u5b50\u6c22\u5316\u7269\u4e2d\u95f4\u4f53\u3002\u540c\u65f6\u901a\u8fc7EPR\u68c0\u6d4b\u624b\u6bb5\uff0c\u9a8c\u8bc1NADH\u7684\u5f62\u6210\u8fc7\u7a0b\u3002\u91d1\u5c5e\u6c22\u5316\u7269\u4e2d\u95f4\u4f53\u5728\u94bc\u57fa\u50ac\u5316\u5242\u4e2d\u7684\u53c2\u4e0e\u4f7fHER\u5177\u6709\u9ad8\u7684\u50ac\u5316\u6d3b\u6027\uff0c\u540c\u65f6\u4e5f\u4e3a\u7535\u5316\u5b66\u50ac\u5316\u5242\u6c22\u5316\u7269\u8f6c\u79fb\u52a9\u529b\u8fd8\u539f\u5f62\u6001\u7684NADH\u518d\u751f\u63d0\u4f9b\u4e86\u65b0\u7684\u53cd\u5e94\u8bbe\u8ba1\u673a\u7406\u3002\u672c\u6587\u7b2c\u4e00\u4f5c\u8005\u4e3aJeremy A. Bau\uff0c\u7814\u7a76\u6210\u679c\u4ee5\u9898\u4e3a\u201cMo3+<\/sup> hydride as the common origin of H2<\/sub> evolution and selective NADH regeneration in molybdenum sulfide electrocatalysts<\/strong>\u201d\uff0c\u53d1\u8868\u5728\u56fd\u9645\u8457\u540d\u671f\u520aNature Catalysis<\/em><\/strong>\u4e0a\u3002<\/p>\n

\"\"<\/p>\n

\u4e09\u3001\u6570\u636e\u6982\u89c8<\/strong><\/p>\n

\u56fe<\/strong>1\u00a0<\/strong>\u6790\u6c22\u8fc7\u7a0b\u4e2d\u7684\u786b\u5316\u94bc\u6a21\u578b\u00a0<\/strong>\u00a9 2022 Springer Nature<\/span><\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>2\u00a0<\/strong>\u4f7f\u7528<\/strong>EPR<\/strong>\u68c0\u6d4b\u548c\u7535\u5316\u5b66\u6d4b\u8bd5\u5206\u6790<\/strong>a-Mosx<\/sub><\/strong>\u4e2d<\/strong>Mo3+<\/sup> <\/strong>\u6c22\u5316\u7269\u00a0<\/strong>\u00a9 2022 Springer Nature<\/span><\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>3\u00a0<\/strong>\u00a0a-Mosx<\/sub><\/strong>\u8fd8\u539f<\/strong>NMN<\/strong>\u7684\u7535\u5316\u5b66\u548c\u5438\u6536\u7279\u6027\u5206\u6790\u56fe\u00a0<\/strong>\u00a9 2022 Springer Nature<\/span><\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>4\u00a0<\/strong>\u00a0NMN <\/strong>\u8fd8\u539f\u4e3a<\/strong>1,4-<\/strong>\u4e8c\u6c22\u5421\u5576\u884d\u751f\u7269\u5206\u6790\u56fe\u00a0<\/strong>\u00a9 2022 Springer Nature<\/span><\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>5\u00a0<\/strong>Mo3+<\/sup><\/strong>\u6c22\u5316\u7269\u5728<\/strong>HER<\/strong>\u548c\u751f\u7269\u50ac\u5316\u4e24\u79cd\u53cd\u5e94\u4e2d\u7684\u5f62\u6210\u56fe<\/strong>\u00a0\u00a9 2022 Springer Nature<\/span><\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>6.<\/strong>\u7535\u50ac\u5316<\/strong> NADH <\/strong>\u518d\u751f\u5e94\u7528\u4e8e\u751f\u7269\u50ac\u5316\u00a0<\/strong>\u00a9 2022 Springer Nature<\/span><\/p>\n

\"\"<\/p>\n

\u56db\u3001\u6210\u679c\u542f\u793a<\/strong><\/p>\n

\u786b\u5316\u94bc\u5728\u7535\u50ac\u5316\u53cd\u5e94\u8fc7\u7a0b\u4e2d\uff0c\u7531\u4e8e\u5728\u6c34\u6eb6\u6db2\u4e2d\u5728\u9634\u6781\u7535\u4f4d\u4e0b\u5f62\u6210 Mo3+<\/sup> \u6c22\u5316\u7269\u6d3b\u6027\u7269\u8d28\u3002\u91d1\u5c5e\u6c22\u5316\u7269\u4f5c\u4e3a\u751f\u7269\u50ac\u5316\u548c\u7535\u50ac\u5316\u4e24\u79cd\u53cd\u5e94\u4e2d\u7684\u4e3b\u8981\u53cd\u5e94\u4e2d\u95f4\u4f53\uff0c\u5f62\u6210\u6c22\u5316\u7269\u7684\u786b\u5316\u94bc\u662f\u7528\u4e8e NADH \u518d\u751f\u7684\u4f4e\u7ecf\u6d4e\u4e14\u826f\u597d\u9009\u62e9\u6027\u7684\u7535\u50ac\u5316\u5242\uff0c\u4ee5\u53ca\u9ad8\u50ac\u5316\u6d3b\u6027\u7684 HER \u50ac\u5316\u5242\u3002\u94bc\u662f\u4e00\u79cd\u5177\u6709\u9ad8\u50ac\u5316\u6d3b\u6027\u7684\u975e\u8d35\u91d1\u5c5e HER \u50ac\u5316\u5242\uff0c\u672c\u7814\u7a76\u4e3a\u8fdb\u4e00\u6b65\u8bbe\u8ba1\u548c\u63a2\u7d22\u94bc\u57fa\u4f5c\u4e3a HER \u50ac\u5316\u5242\u3002\u540c\u65f6\uff0c\u4e5f\u5c06\u786b\u5316\u94bc\u7535\u50ac\u5316\u5242\u5728\u6392\u9664\u5355\u7535\u5b50\u8f6c\u79fb\u7684\u60c5\u51b5\u4e0b\u5f62\u6210\u548c\u8f6c\u79fb\u6c22\u5316\u7269\uff0c\u52a9\u529b\u751f\u7269\u50ac\u5316\u5e94\u7528\u5f00\u8f9f\u4e86\u4e00\u6761\u5177\u6709\u6210\u672c\u6548\u76ca\u7684\u9014\u5f84\uff0c\u4e3a\u7535\u50ac\u5316\u5242\u8bbe\u8ba1\u914d\u5408\u5176\u4ed6\u53cd\u5e94\u673a\u5236\u6307\u660e\u4e86\u65b9\u5411\u3002<\/p>\n

\u53c2\u8003\u6587\u732e\uff1aBau, J.A., Emwas, AH., Nikolaienko, P. et al. Mo3+ hydride as the common origin of H2<\/sub> evolution and selective NADH regeneration in molybdenum sulfide electrocatalysts. Nat Catal<\/em> (2022). https:\/\/doi.org\/10.1038\/s41929-022-00781-8<\/a><\/p>\n

\u672c\u6587\u7531\u91d1\u7235\u4f9b\u7a3f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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