{"id":241502,"date":"2022-08-27T06:29:38","date_gmt":"2022-08-26T22:29:38","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=241502"},"modified":"2022-08-26T18:29:43","modified_gmt":"2022-08-26T10:29:43","slug":"%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e6%96%b0%e7%ad%96%e7%95%a5%ef%bc%81nat-commun%ef%bc%9a%e6%97%a0%e6%9c%ba%e7%ba%b3%e7%b1%b3%e7%89%87%e9%80%9a%e8%bf%87%e8%b0%83%e8%8a%82%e5%85%8d%e7%96%ab%e5%85%b1","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=241502","title":{"rendered":"\u514d\u75ab\u6cbb\u7597\u65b0\u7b56\u7565\uff01Nat. Commun\uff1a\u65e0\u673a\u7eb3\u7c73\u7247\u901a\u8fc7\u8c03\u8282\u514d\u75ab\u5171\u523a\u6fc0\u9014\u5f84\u4fc3\u8fdb\u9488\u5bf9\u533b\u7597\u690d\u5165\u7269\u611f\u67d3\u7684\u4f53\u6db2\u514d\u75ab"},"content":{"rendered":"<p><strong>lwb<\/strong><\/p>\n<p><strong>01<\/strong><strong>\u3001\u5bfc\u8bfb<\/strong><\/p>\n<p>\u533b\u5b66\u690d\u5165\u7269\u5df2\u7ecf\u5f7b\u5e95\u6539\u53d8\u4e86\u533b\u5b66\uff0c\u4f46\u5b83\u4eec\u6b63\u9762\u4e34\u5fae\u751f\u7269\u751f\u7269\u819c\u5f62\u6210\u98ce\u9669\u7684\u5a01\u80c1\u3002\u751f\u7269\u819c\u5185\u5e87\u62a4\u7684\u5165\u4fb5\u75c5\u539f\u4f53\u5177\u6709\u9ad8\u5ea6\u8010\u836f\u6027\uff0c\u4f1a\u5bfc\u81f4\u6301\u7eed\u5fae\u751f\u7269\u611f\u67d3\uff0c\u4e25\u91cd\u5f71\u54cd\u516c\u5171\u536b\u751f\u5b89\u5168\u3002\u751f\u7269\u819c\u5fae\u73af\u5883\u4f1a\u4f7f\u5f97\u5bbf\u4e3b\u514d\u75ab\u7ec6\u80de\u5411\u6297\u708e\u8868\u578b\u6781\u5316\u3002\u8fd1\u5e74\u6765\uff0c\u9776\u5411\u8c03\u63a7\u5bbf\u4e3b\u514d\u75ab\u9632\u5fa1\u6210\u4e3a\u6297\u83cc\u540e\u6297\u751f\u7269\u819c\u7b56\u7565\u7684\u524d\u6cbf\u7814\u7a76\u65b9\u5411\u3002<\/p>\n<p>\u5728\u514d\u75ab\u8c03\u8282\u7b56\u7565\u4e0a\uff0c\u672a\u6765\u611f\u67d3\u6027\u514d\u75ab\u6cbb\u7597\u53ef\u80fd\u901a\u8fc7\u8bf1\u5bfc\u9776\u5411\u4e2d\u548c\u6297\u4f53\u548c\u5bf9\u751f\u7269\u819c\u7684\u6301\u4e45\u8bb0\u5fc6\u53cd\u5e94\u6765\u50ac\u5316\u3002\u4f46\u5728\u8bbe\u8ba1\u5178\u578b\u751f\u7269\u819c\u6e05\u9664\u7684\u9002\u5e94\u6027\u514d\u75ab\u8c03\u8282\u7b56\u7565\u65f6\u5b58\u5728\u4e00\u4e9b\u969c\u788d\uff1a<\/p>\n<ul>\n<li>\u751f\u7269\u819c\u4e2d\u7684\u7ec6\u83cc\u76f8\u5173\u6297\u539f\uff08BAA\uff09\u514d\u75ab\u539f\u6027\u5dee\u5c06\u5bfc\u81f4\u6297\u539f\u5448\u9012\u4e0d\u8db3\u548c\u968f\u540e\u7684T\u7ec6\u80de\u542f\u52a8\u548c\u6fc0\u6d3b\u3002<\/li>\n<li>\u901a\u8fc7\u6a21\u62df\u514d\u75ab\u51b7\u5fae\u73af\u5883\uff0c\u4f1a\u5f62\u6210\u514d\u75ab\u6291\u5236\u7684\u751f\u6001\u4f4d\uff0c\u5305\u62ec\u6297\u539f\u5448\u9012\u7ec6\u80de\uff08APC\uff09\u8017\u5c3d\u3001T\u7ec6\u80de\u542f\u52a8\u65e0\u6548\u3001\u6297\u4f53\u53cd\u5e94\u51cf\u5f31\u7b49\u3002<\/li>\n<li>\u611f\u67d3\u6027\u751f\u7269\u819c\u4f1a\u5f15\u8d77\u514d\u75ab\u6291\u5236\u7ec6\u80de\uff08\u8c03\u8282\u6027T\u7ec6\u80de\uff09\u7684\u5f02\u5e38\u6fc0\u6d3b\uff0c\u9650\u5236\u4e86\u53c2\u4e0e\u751f\u7269\u819c\u6cbb\u7597\u6d3b\u6027\u6297\u4f53\u7684\u6570\u91cf\u3002<\/li>\n<\/ul>\n<p>\u73b0\u5982\u4eca\uff0c\u7eb3\u7c73\u6280\u672f\u5e94\u7528\u4e8e\u514d\u75ab\u6cbb\u7597\u8fdb\u6b65\u663e\u8457\uff0c\u5b83\u5177\u6709\u5185\u5728\u7684\u514d\u75ab\u8c03\u8282\u529f\u80fd\u3001\u4f18\u5316\u7684\u6297\u539f\u5448\u9012\u3001\u6301\u7eed\u7684\u514d\u75ab\u53cd\u5e94\u8bf1\u5bfc\u7b49\u4f18\u70b9\u3002\u76ee\u524d\uff0c\u542b\u9530(Mn)\u3001\u7852(Se)\u6216\u78f7(P)\u7684\u65e0\u673a\u7eb3\u7c73\u6750\u6599\u662f\u6f5c\u5728\u7684\u514d\u75ab\u523a\u6fc0\u5019\u9009\u6750\u6599\u3002\u4e8c\u7ef4\u786b\u4ee3\u78f7\u9178\u9530MnPSe<sub>3<\/sub>\u7eb3\u7c73\u7247\uff08MPS NS\uff09\u6750\u6599\u4f5c\u4e3a\u6cbb\u7597\u690d\u5165\u7269\u611f\u67d3\u7684\u65e0\u673a\u514d\u75ab\u523a\u6fc0\u5242\u6709\u5f85\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u3002<\/p>\n<p><strong>02<\/strong><strong>\u3001\u6210\u679c\u63a0\u5f71<\/strong><\/p>\n<p>\u5728\u6b64\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u4e0a\u6d77\u7845\u9178\u76d0\u7814\u7a76\u6240\u6797\u701a\u526f\u7814\u7a76\u5458\u3001\u65bd\u5251\u6797\u9662\u58eb\u56e2\u961f\u8054\u5408\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u9644\u5c5e\u7b2c\u516d\u4eba\u6c11\u533b\u9662\u9aa8\u79d1\u4e3b\u4efb\u533b\u5e08\u5f20\u5148\u9f99\u6559\u6388\u8fdb\u884c\u4e86\u6297\u751f\u7269\u819c\u611f\u67d3\u7684\u7814\u7a76\u3002\u7814\u7a76\u8bc1\u660e\u7528\u805a\u4e59\u70ef\u5421\u54af\u70f7\u916e\uff08PVP\uff09\u4fee\u9970\u7684\u4e8c\u7ef4\u786b\u4ee3\u78f7\u9178\u9530MnPSe<sub>3 <\/sub>\uff08MPS\uff09\u7eb3\u7c73\u7247\u80fd\u591f\u901a\u8fc7\u8c03\u8282\u611f\u67d3\u6027\u5fae\u73af\u5883\uff08IME\uff09\u4e2d\u7684\u6297\u539f\u5448\u9012\u548c\u5171\u523a\u6fc0\u5206\u5b50\u8868\u8fbe\u5728\u5916\u79d1\u690d\u5165\u7269\u611f\u67d3\u7684\u5c0f\u9f20\u6a21\u578b\u4e2d\u89e6\u53d1\u5f3a\u7684\u6297\u83cc\u751f\u7269\u819c\u4f53\u6db2\u514d\u75ab\u3002\u4ece\u673a\u7406\u4e0a\u8bb2\uff0cPVP\u4fee\u9970\u7684MPS\uff08MPS-PVP\uff09\u901a\u8fc7\u4ea7\u751f\u6d3b\u6027\u6c27\u5316\u7269\u8d28\u7834\u574f\u751f\u7269\u819c\u7684\u7ed3\u6784\uff0c\u4ece\u800c\u5bfc\u81f4\u6297\u539f\u66b4\u9732\uff0c\u540c\u65f6\u6539\u53d8\u514d\u75ab\u6291\u5236\u4fe1\u53f7\uff08IL4I1\u548cCD206\uff09\u548c\u5171\u6fc0\u6d3b\u4fe1\u53f7\uff08CD40\u3001CD80\u548cCD69\uff09\u7684\u5e73\u8861\u3002\u8fd9\u5bfc\u81f4\u6269\u589e\u7684APC\u542f\u52a8\u548c\u6297\u539f\u5448\u9012\uff0c\u5bfc\u81f4\u751f\u7269\u819c\u7279\u5f02\u6027\u4f53\u6db2\u514d\u75ab\u548c\u8bb0\u5fc6\u53cd\u5e94\u3002\u8be5\u7814\u7a76\u8bc1\u660e\u4e86\u672f\u524d\u4f7f\u7528MPS-PVP\u7684\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u53ef\u4ee5\u6210\u529f\u51cf\u8f7b\u79fb\u9664\u53d7\u611f\u67d3\u690d\u5165\u7269\u540e\u6b8b\u7559\u548c\u590d\u53d1\u7684\u611f\u67d3\u98ce\u9669\uff0c\u8be5\u7814\u7a76\u63d0\u4f9b\u4e86\u4e00\u79cd\u66ff\u4ee3\u6297\u751f\u7d20\u6cbb\u7597\u751f\u7269\u819c\u611f\u67d3\u7684\u65b9\u6cd5\u3002<\/p>\n<p>\u76f8\u5173\u7814\u7a76\u6210\u679c\u4ee5\u201c<strong><em>Inorganic nanosheets facilitate humoral immunity against medical implant infections by modulating immune co-stimulatory\u00a0<\/em><\/strong><strong><em>pathways<\/em><\/strong>\u201d\u4e3a\u9898\u53d1\u8868\u5728<strong><em>Nature Communications<\/em><\/strong>\u4e0a\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241503\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72471-4.png\" alt=\"\" width=\"692\" height=\"269\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72471-4.png 692w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72471-4-300x117.png 300w\" sizes=\"(max-width: 692px) 100vw, 692px\" \/><\/p>\n<p><strong>03<\/strong><strong>\u3001\u6838\u5fc3\u521b\u65b0\u70b9<\/strong><\/p>\n<p>1\u3001\u7814\u7a76\u7528\u805a\u4e59\u70ef\u5421\u54af\u70f7\u916e(PVP)\u4fee\u9970\u7684MPS\u7eb3\u7c73\u7247\u6750\u6599\u80fd\u591f\u5728\u5916\u79d1\u690d\u5165\u7269\u611f\u67d3\u7684\u5c0f\u9f20\u6a21\u578b\u4e2d\u89e6\u53d1\u5f3a\u5927\u7684\u6297\u83cc\u751f\u7269\u819c\u4f53\u6db2\u514d\u75ab\u3002<\/p>\n<p>2\u3001MPS-PVP\u8fd8\u80fd\u4fc3\u8fdb\u7ec6\u83cc\u7279\u5f02\u6027\u7684\u6297\u4f53\u53cd\u5e94\uff0c\u4ece\u800c\u9632\u6b62\u672f\u540e\u611f\u67d3\u590d\u53d1\uff0c\u8be5\u7814\u7a76\u63d0\u4f9b\u4e86\u4e00\u79cd\u66ff\u4ee3\u6297\u751f\u7d20\u6cbb\u7597\u751f\u7269\u819c\u611f\u67d3\u7684\u524d\u6cbf\u65b9\u6cd5\u3002<\/p>\n<p><strong>04<\/strong><strong>\u3001\u6570\u636e\u6982\u89c8<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241504\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72472-5.png\" alt=\"\" width=\"820\" height=\"732\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72472-5.png 820w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72472-5-300x268.png 300w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72472-5-768x686.png 768w\" sizes=\"(max-width: 820px) 100vw, 820px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>1 <\/strong><strong>\u514d\u75ab\u523a\u6fc0\u6027<\/strong><strong>MPS-PVP<\/strong><strong>\u7528\u4e8e\u8bf1\u5bfc\u6297\u751f\u7269\u819c\u4f53\u6db2\u514d\u75ab\u548c\u5b9e\u73b0\u672f\u524d\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u7684\u793a\u610f\u56fe<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241505\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72473-5.png\" alt=\"\" width=\"888\" height=\"1137\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72473-5.png 888w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72473-5-234x300.png 234w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72473-5-768x983.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72473-5-800x1024.png 800w\" sizes=\"(max-width: 888px) 100vw, 888px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>2 MPS<\/strong><strong>\u7684\u5236\u5907\u548c\u8868\u5f81<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p>\uff08a\uff09 MPS\u5408\u6210\u53ca\u5176\u5206\u5b50\u7ed3\u6784\u793a\u610f\u56fe\uff1b<\/p>\n<p>\uff08b\uff09 \u5757\u72b6MPS\u7684SEM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08c\uff09 MPS NSs\u7684TEM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08d\uff09 \u5757\u72b6MPS\u548cMPS NSs\u7684\u62c9\u66fc\u5149\u8c31\uff1b<\/p>\n<p>\uff08e\uff09 MPS NSs\u7684\u5143\u7d20\u6620\u5c04\uff1b<\/p>\n<p>\uff08f\uff09 MPS NSs\u7684\u5178\u578bAFM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08g\uff09 MPS NSs\u7684\u539a\u5ea6\u5206\u5e03\u5206\u6790\uff1b<\/p>\n<p>\uff08h\uff09 MPS NSs\u7684\u6a2a\u5411\u5c3a\u5bf8\u5206\u5e03\u5206\u6790\uff1b<\/p>\n<p>\uff08i\uff09 \u4e0d\u540cpH\u6761\u4ef6\u4e0bMPS-NSs\u50ac\u5316\u6c27\u5316DPBF\uff1b<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241506\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72474-4.png\" alt=\"\" width=\"1008\" height=\"1061\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72474-4.png 1008w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72474-4-285x300.png 285w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72474-4-768x808.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72474-4-973x1024.png 973w\" sizes=\"(max-width: 1008px) 100vw, 1008px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>3 MPS-PVP<\/strong><strong>\u5229\u7528\u751f\u7269\u819c\u4f5c\u4e3a\u5185\u6e90\u6027\u6297\u539f\u6c89\u79ef<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p>\uff08a\uff09 \u751f\u7269\u819c\u7684\u4e09\u7ef4\u5171\u7126\u663e\u5fae\u7167\u7247\uff1b<\/p>\n<p>\uff08b\uff09 \u751f\u7269\u819c\u751f\u7269\u91cf\u7684\u5b9a\u91cf\u5206\u6790\uff1b<\/p>\n<p>\uff08c\uff09 \u751f\u7269\u819c\u7684SEM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08d\uff0cf\uff09 \u63d0\u53d6\u751f\u7269\u819c\u4e0aSyto9\/PI\u67d3\u8272\u7684\u4ee3\u8868\u6027\u6d41\u5f0f\u7ec6\u80de\u672f\u56fe\u548c\u5b9a\u91cf\u5206\u6790\uff1b<\/p>\n<p>\uff08e\uff0cg\uff09 DCFH-DA\u67d3\u8272\u751f\u7269\u819c\u7684\u6d41\u5f0f\u7ec6\u80de\u672f\u5206\u6790\u68c0\u6d4b\u6d3b\u6027\u6c27\uff1b<\/p>\n<p>\uff08h\uff09 MPS-PVP\u589e\u5f3a\u751f\u7269\u819c\u6297\u539f\u8868\u8fbe\u7684\u793a\u610f\u56fe\uff1b<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241507\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72475-5.png\" alt=\"\" width=\"1141\" height=\"1415\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72475-5.png 1141w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72475-5-242x300.png 242w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72475-5-768x952.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72475-5-826x1024.png 826w\" sizes=\"(max-width: 1141px) 100vw, 1141px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>4 MPS-PVP<\/strong><strong>\u6fc0\u6d3b<\/strong><strong>RAW264.7<\/strong><strong>\u5de8\u566c\u7ec6\u80de\u4e2d\u7684\u5171\u523a\u6fc0\u9014\u5f84<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p>\uff08a\uff09 \u706b\u5c71\u56fe\u663e\u793a\u4e86\u4e0d\u540c\u7ec4\u4e2d\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\uff1b<\/p>\n<p>\uff08b\uff09 KEGG\u5bcc\u96c6\u5206\u6790\u63ed\u793a\u4e86MPS-PVP\u8c03\u8282\u7684\u524d20\u4e2a\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\u7684\u751f\u7269\u8fc7\u7a0b\uff1b<\/p>\n<p>\uff08c\uff09 MPS-PVP\u5904\u7406\u540e\u5de8\u566c\u7ec6\u80de\u4ee3\u8868\u6027\u514d\u75ab\u4fe1\u53f7\u901a\u8def\u7684\u57fa\u56e0\u96c6\u5bcc\u96c6\u5206\u6790\uff1b<\/p>\n<p>\uff08d\uff09 \u663e\u793aMPS-PVP\u5904\u7406\u540eDEG\u7684\u70ed\u56fe\uff1b<\/p>\n<p>\uff08e\uff09 \u5de8\u566c\u7ec6\u80de\u4e2d\u4e0e\u7ec6\u80de\u7c98\u9644\u5206\u5b50\u76f8\u5173\u57fa\u56e0\u7684\u57fa\u56e0-\u57fa\u56e0\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\uff1b<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241508\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72476-2.png\" alt=\"\" width=\"1060\" height=\"1145\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72476-2.png 1060w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72476-2-278x300.png 278w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72476-2-768x830.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72476-2-948x1024.png 948w\" sizes=\"(max-width: 1060px) 100vw, 1060px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>5 <\/strong><strong>\u514d\u75ab\u523a\u6fc0\u6027<\/strong><strong>MPS-PVP<\/strong><strong>\u4fc3\u8fdb<\/strong><strong>RAW264.7<\/strong><strong>\u5de8\u566c\u7ec6\u80de\u7684\u6297\u539f\u5904\u7406\u548c\u5448\u9012<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p>\uff08a\uff09 RAW264.7\u5de8\u566c\u7ec6\u80de\u7684iNOS\uff08\u7eff\u8272\uff09\u3001CD206\uff08\u7ea2\u8272\uff09\u548cDAPI\uff08\u84dd\u8272\uff09\u514d\u75ab\u8367\u5149\u67d3\u8272\uff1b<\/p>\n<p>\uff08b\uff0cc\uff09 \u6d41\u5f0f\u7ec6\u80de\u672f\u5206\u6790\u663e\u793a\u4e0d\u540c\u5904\u7406\u540eRAW264.7\u5de8\u566c\u7ec6\u80de\u4e2dCCR7\uff08M1\u6807\u8bb0\uff09\u548cCD206\uff08M2\u6807\u8bb0\uff09\u8868\u8fbe\u7684\u53d8\u5316\uff1b<\/p>\n<p>\uff08d\uff09 \u6307\u5b9a\u5904\u7406\u540eRAW264.7\u5de8\u566c\u7ec6\u80de\u4e0a\u6e05\u6db2\u4e2dTNF\u03b1\u3001IL1\u03b2\u3001IL6\u548cIL12\u7684\u6d53\u5ea6\uff1b<\/p>\n<p>\uff08e\uff09 \u8367\u5149\u67d3\u8272\u663e\u793aRAW264.7\u5de8\u566c\u7ec6\u80de\uff08\u7ea2\u8272\uff09\u548c\u7ec6\u83cc\uff08\u7eff\u8272\uff09\u63a5\u79cd\u540e60\u5206\u949f\u7684\u7ec6\u83cc\u541e\u566c\u4f5c\u7528\uff1b<\/p>\n<p>\uff08f\uff0cg\uff09 \u5177\u6709\u4ee3\u8868\u6027\u7684\u6d41\u5f0f\u7ec6\u80de\u672f\u56fe\uff08f\uff09\u548c\u5b9a\u91cf\uff08g\uff09\u663e\u793a\u4e86RAW264.7\u5de8\u566c\u7ec6\u80de\u5bf9\u7ec6\u83cc\u7684\u541e\u566c\u6e05\u9664\u7387\uff1b<\/p>\n<p>\uff08h\uff09 \u7ef4\u6301\u5de8\u566c\u7ec6\u80de\u4fc3\u708e\u8868\u578b\u7684MPS-PVP\u793a\u610f\u56fe\uff1b<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241509\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72477-1.png\" alt=\"\" width=\"1121\" height=\"1401\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72477-1.png 1121w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72477-1-240x300.png 240w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72477-1-768x960.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72477-1-819x1024.png 819w\" sizes=\"(max-width: 1121px) 100vw, 1121px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>6 <\/strong><strong>\u514d\u75ab\u523a\u6fc0\u6027<\/strong><strong>MPS-PVP<\/strong><strong>\u5141\u8bb8\u4f9d\u8d56\u4e8e\u4f53\u6db2\u514d\u75ab\u7684\u751f\u7269\u819c\u63a7\u5236<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p>\uff08a\uff09 \u201c\u539f\u4f4d\u201d\u690d\u5165MRSA\u611f\u67d3\u6a21\u578b\u7684\u5236\u5907\u548cMPS-PVP\u6cbb\u7597\u65b9\u6848\uff1b<\/p>\n<p>\uff08b\uff0cc\uff09 \u6307\u793a\u6cbb\u7597\u540e\u53d7\u611f\u67d3\u5c0f\u9f20\u7684\u4e2a\u4f53\u611f\u67d3\u9762\u79ef\u751f\u957f\u66f2\u7ebf\u548c\u4ee3\u8868\u6027\u7167\u7247\uff08b\uff09\u548c\u5e73\u5747\u611f\u67d3\u9762\u79ef\u589e\u957f\u66f2\u7ebf\uff08c\uff09\uff1b<\/p>\n<p>\uff08d\uff0ce\uff09 \u611f\u67d3\u5c0f\u9f20\u63d0\u53d6\u7684\u690d\u5165\u7269\uff08d\uff09\u548c\u690d\u5165\u7269\u5468\u56f4\u7ec4\u7ec7\uff08e\uff09\u7684\u7ec6\u83ccCFU\u8ba1\u6570\uff1b<\/p>\n<p>\uff08f\uff09 \u4f53\u5185\u751f\u7269\u819c\u5f62\u6210\u7684\u5178\u578bSEM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08g\uff0ck\uff09M1\u8868\u578b\u5de8\u566c\u7ec6\u80de\uff08CD80<sup>+<\/sup>CD206<sup>\u2212<\/sup>\uff09\u7684\u4ee3\u8868\u6027\u6d41\u5f0f\u7ec6\u80de\u672f\u56fe\uff0c\u901a\u8fc7\u5728\u89e3\u5256\u7684IDLNs\u4e2d\u5bf9CD11b<sup>+<\/sup>F4\/80<sup>+<\/sup>\u7ec6\u80de\uff08g\uff09\u3001\u6210\u719fDCs\uff08CD80<sup>+<\/sup>CD86<sup>+<\/sup>\uff09\u548cCD11c<sup>+ <\/sup>MHC-II<sup>+<\/sup>\u7ec6\u80de\uff08h\uff09\u3001CD4<sup>+ <\/sup>T\u7ec6\u80de\uff08CD4<sup>+<\/sup>\uff09\u3001CD3<sup>+<\/sup>T\u7ec6\u80de\uff08i\uff09\u3001\u6d46\u6bcd\u7ec6\u80de\uff08CD138<sup>+<\/sup>CD19<sup>+<\/sup>\uff09\u548c\u6d46\u7ec6\u80de\uff08CD138<sup>+<\/sup>CD19<sup>\u2212<\/sup>) \u95e8\u63a7\uff0c\u5bf9CD45<sup>+<\/sup>\u7ec6\u80de\uff08j\uff09\u548cT<sub>reg<\/sub>s\uff08Foxp3<sup>+<\/sup>\uff09\u3001CD3<sup>+<\/sup>CD4<sup>+ <\/sup>T\u7ec6\u80de\uff08k\uff09\u540e\u95e8\u63a7\uff1b<\/p>\n<p>\uff08l\uff09 g\u2013k\u4e2d\u76f8\u5e94\u514d\u75ab\u7ec6\u80de\u7fa4\u7684\u5b9a\u91cf\u5206\u6790\uff1b<\/p>\n<p>\uff08m\uff09 \u611f\u67d3\u7ec4\u7ec7\u4e2d\u7ec6\u80de\u56e0\u5b50\u7684\u8868\u8fbe\u8c31\uff1b<\/p>\n<p>\uff08n\uff09 \u4e0d\u540c\u5904\u7406\u7684\u5c0f\u9f20\u8840\u6e05\u6297\u4f53\u6c34\u5e73\uff1b<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-241510\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72478.png\" alt=\"\" width=\"1068\" height=\"1300\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72478.png 1068w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72478-246x300.png 246w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72478-768x935.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/08\/\u56fe\u72478-841x1024.png 841w\" sizes=\"(max-width: 1068px) 100vw, 1068px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>7 <\/strong><strong>\u672f\u524d\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u4e3a\u9884\u9632\u611f\u67d3\u590d\u53d1\u63d0\u4f9b\u4e86\u957f\u671f\u4f53\u6db2\u514d\u75ab\u4fdd\u62a4<\/strong> <strong>\u00a9 2022 The Author(s)<\/strong><\/p>\n<p>\uff08a\uff09 \u9884\u9632\u672f\u540eMRSA\u611f\u67d3\u590d\u53d1\u7684\u672f\u524d\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u793a\u610f\u56fe\uff1b<\/p>\n<p>\uff08b\uff09 \u5904\u7406\u540e\u5c0f\u9f20\u7684\u4e2a\u4f53\u611f\u67d3\u9762\u79ef\u751f\u957f\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08c\uff09 \u5904\u7406\u540e\u5c0f\u9f20\u7684\u5e73\u5747\u611f\u67d3\u9762\u79ef\u751f\u957f\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08d\uff09 \u672f\u524d\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u6a21\u578b\u4e2d\u63d0\u53d6\u690d\u5165\u7269\u7684\u7ec6\u83ccCFU\u8ba1\u6570\uff1b<\/p>\n<p>\uff08e\uff09 \u672f\u524d\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u6a21\u578b\u4e2d\u690d\u5165\u7269\u5468\u56f4\u7ec4\u7ec7\u7684\u7ec6\u83ccCFU\u8ba1\u6570\uff1b<\/p>\n<p>\uff08f\uff09 \u5904\u7406\u540e\u5c0f\u9f20\u7684\u4ee3\u8868\u6027\u7167\u7247\uff1b<\/p>\n<p>\uff08g\uff09 \u611f\u67d3\u533a\u57df\u7ec4\u7ec7HE\u67d3\u8272\u7684\u4ee3\u8868\u6027\u56fe\u50cf\uff1b<\/p>\n<p>\uff08h\uff09 \u4f7f\u7528Giemsa\u67d3\u8272\u5206\u6790\u7ec6\u83cc\u751f\u7269\u91cf\u7684\u7ec4\u7ec7\u5207\u7247\u7684\u4ee3\u8868\u6027\u56fe\u50cf\uff1b<\/p>\n<p>\uff08i\uff09 \u901a\u8fc7\u5bf9B220<sup>+<\/sup>\u7ec6\u80de\u95e8\u63a7\u7684\u8bb0\u5fc6B\u7ec6\u80de\u7684\u4ee3\u8868\u6027\u6d41\u52a8\u70b9\u56fe\uff1b<\/p>\n<p>\uff08j\uff09 \u901a\u8fc7\u5bf9B220+\u7ec6\u80de\u95e8\u63a7\u7684\u8bb0\u5fc6B\u7ec6\u80de\u7684\u7edf\u8ba1\u5206\u6790\uff1b<\/p>\n<p>\uff08k\uff09 CD80<sup>+<\/sup>B<sub>mem<\/sub>\u7684\u4ee3\u8868\u6027\u6d41\u70b9\u56fe\uff1b<\/p>\n<p>\uff08l\uff09 CD80<sup>+<\/sup>Bmem\u7684\u7edf\u8ba1\u5206\u6790\uff1b<\/p>\n<p>\uff08m\uff09 \u8840\u6e05\u4e2dIL1\u03b2\u7ec6\u80de\u56e0\u5b50\u7684\u6c34\u5e73\uff1b<\/p>\n<p>\uff08n\uff09 \u4e0d\u540c\u4eba\u7fa4\u8840\u6e05IgG\u6297\u4f53\u6c34\u5e73\uff1b<\/p>\n<p><strong>05<\/strong><strong>\u3001\u6210\u679c\u542f\u793a<\/strong><\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u8be5\u7814\u7a76\u5408\u6210\u4e86\u4e00\u79cd2D\u65e0\u673aMPS\u7eb3\u7c73\u7247\uff0c\u5e76\u7814\u7a76\u4e86\u5176\u5728\u6cbb\u7597\u690d\u5165\u7269\u611f\u67d3\u65f6\u523a\u6fc0\u6297\u83cc\u751f\u7269\u819c\u4f53\u6db2\u514d\u75ab\u7684\u6f5c\u529b\uff0cMPS\u7eb3\u7c73\u7247\u7531Mn\u3001Se\u548cP\u5143\u7d20\u7ec4\u6210\uff0c\u8fd9\u4e9b\u5143\u7d20\u90fd\u5728\u514d\u75ab\u6d3b\u6027\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002\u91c7\u7528\u805a\u4e59\u70ef\u5421\u54af\u70f7\u916e\uff08PVP\uff09\u8fdb\u4e00\u6b65\u4fee\u9970MPS\u7eb3\u7c73\u7247\uff0c\u968f\u540e\u6784\u5efa\u4e86MRSA\u690d\u5165\u7269\u611f\u67d3\u7684\u5c0f\u9f20\u6a21\u578b\uff0c\u8bc4\u4ef7\u4e86MPS-PVP\u5728\u5176\u4f53\u5185\u7684\u6297\u83cc\u548c\u514d\u75ab\u8c03\u8282\u4f5c\u7528\u3002\u539f\u4f4d\u690d\u5165\u7269\u611f\u67d3\u6a21\u578b\u663e\u793a\uff0c\u6ce8\u5c04MPS-PVP\u540e\uff0c\u4f53\u6db2\u514d\u75ab\u6fc0\u6d3b\u548c\u6297\u751f\u7269\u819c\u6548\u679c\u826f\u597d\u3002IDLN\u4e2dAPC\u3001T\u7ec6\u80de\u548c\u8840\u6d46B\u7ec6\u80de\u7684\u8868\u578b\u8f6c\u53d8\u4ee5\u53ca\u8840\u6db2\u4e2d\u7684\u7ec6\u80de\u56e0\u5b50\u548c\u6297\u4f53\u6c34\u5e73\u8bc1\u660e\u4e86MPS\u5728\u4f53\u5185\u5177\u6709\u663e\u8457\u7684\u514d\u75ab\u523a\u6fc0\u4f5c\u7528\u3002\u603b\u7684\u6765\u8bf4\uff0c\u8fd9\u79cd\u65e0\u673a\u514d\u75ab\u523a\u6fc0\u5e73\u53f0\u63d0\u4f9b\u4e86\u6bd4\u5e38\u89c4\u6297\u751f\u7d20\u6cbb\u7597\u66f4\u5168\u9762\u7684\u4f53\u6db2\u514d\u75ab\u6fc0\u6d3b\u548c\u66f4\u5f3a\u7684\u751f\u7269\u819c\u6e05\u9664\u6548\u679c\u3002\u8fd9\u9879\u7814\u7a76\u5c06\u6fc0\u52b1\u5728\u5b9e\u65bd\u8fd9\u79cd\u65b0\u578b\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\u4e4b\u524d\uff0c\u5728\u8bbe\u8ba1\u5177\u6709\u514d\u75ab\u523a\u6fc0\u6548\u5e94\u7684\u7eb3\u7c73\u6750\u6599\u65b9\u9762\u7ee7\u7eed\u521b\u65b0\u3002<\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5\uff1a<\/strong><strong>Inorganic nanosheets facilitate humoral immunity against medical implant infections by modulating immune co-stimulatory pathways<\/strong><strong>\uff0c<\/strong><strong>2022<\/strong><strong>\uff0c<\/strong><strong>https:\/\/doi.org\/10.1038\/s41467-022-32405-x<\/strong><strong>\uff09<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>lwb 01\u3001\u5bfc\u8bfb 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