{"id":244298,"date":"2022-11-26T06:06:08","date_gmt":"2022-11-25T22:06:08","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=244298"},"modified":"2022-11-25T22:06:54","modified_gmt":"2022-11-25T14:06:54","slug":"nat-commun-%e9%80%9a%e8%bf%87%e5%be%ae%e9%92%88%e8%87%aa%e4%be%9b%e7%94%b5%e7%bb%8f%e7%9a%ae%e7%94%b5%e5%88%ba%e6%bf%80%e6%94%b9%e5%96%84%e8%a1%a8%e7%9a%ae%e7%94%9f%e9%95%bf%e5%9b%a0%e5%ad%90","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=244298","title":{"rendered":"Nat. 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style=\"text-align: center;\"><strong>\u4e8c\u3001\u3010\u6210\u679c\u63a0\u5f71\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c\u4e2d\u79d1\u9662\u5317\u4eac\u7eb3\u7c73\u80fd\u6e90\u4e0e\u7cfb\u7edf\u7814\u7a76\u6240\u674e\u821f\u7814\u7a76\u5458\u3001\u7f57\u8043\u7814\u7a76\u5458\u4e0e\u7b2c\u4e09\u519b\u533b\u5927\u5b66\u897f\u5357\u533b\u9662\u5f20\u5bb6\u5e73\u4e3b\u4efb\u7b49\u4eba\u901a\u8fc7\u96c6\u6210\u6ed1\u52a8\u5f0f\u6469\u64e6\u7eb3\u7c73\u53d1\u7535\u673a\uff08sf-TENG\uff09\u548c\u4e24\u6bb5\u5f0f\u5fae\u9488\u91ca\u836f\u8d34\u7247\uff08CMNP\uff09\uff0c\u5f00\u53d1\u4e86\u57fa\u4e8e\u5fae\u9488\u7684\u81ea\u4f9b\u7535\u7ecf\u76ae\u7535\u523a\u6fc0\u7cfb\u7edf\uff08mn-STESS\uff09\uff0c\u5728\u591a\u4e2a\u5c42\u9762\u6539\u5584\u4e86EGF\u5728\u7528\u4e8e\u4f24\u53e3\u6108\u5408\u65f6\u7684\u836f\u6548\u3002CMNP\u53ef\u7a7f\u900f\u89d2\u8d28\u5c42\uff0c\u5e76\u6301\u7eed\u91ca\u653eEGF\u8fbe24 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stimulation\u201d\u4e3a\u9898\u53d1\u8868\u4e8e\u56fd\u9645\u77e5\u540d\u671f\u520a\u300a<em>Nature Communications<\/em>\u300b\u4e0a\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-244299\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/0-10.png\" alt=\"\" width=\"1085\" height=\"584\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/0-10.png 1085w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/0-10-300x161.png 300w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/0-10-768x413.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/0-10-1024x551.png 1024w\" sizes=\"(max-width: 1085px) 100vw, 1085px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u4e09\u3001\u3010\u6838\u5fc3\u521b\u65b0\u70b9\u3011<\/strong><\/p>\n<p>1\u3001mn-STESS\u5229\u7528\u5fae\u9488\u523a\u7a7f\u89d2\u8d28\u5c42\uff0c\u5e76\u5c06EGF\u6301\u7eed\u9012\u9001\u81f3\u771f\u76ae\u5c42\u4e2d\uff0c\u6539\u5584\u4e86\u836f\u7269\u7684\u6e17\u900f\u6027\uff1b<\/p>\n<p>2\u3001mn-STESS\u4e2d\u6574\u5408\u7684sf-TENG\u5c06\u624b\u6307\u6ed1\u52a8\u7684\u673a\u68b0\u80fd\u8f6c\u5316\u4e3a\u7535\u80fd\uff0c\u5e76\u901a\u8fc7\u5bfc\u7535\u5fae\u9488\u65bd\u52a0\u7ecf\u76ae\u7535\u523a\u6fc0\u3002mn-STESS\u65bd\u52a0\u7684\u7535\u523a\u6fc0\u53ef\u4ee5\u4f5c\u4e3aEGF\u7684\u201c\u8f85\u52a9\u5242\u201d\uff1a\u4e0d\u4ec5\u6291\u5236\u4e86GSH\u5bf9EGF\u7684\u8fd8\u539f\uff1b\u540c\u65f6\u4e0a\u8c03\u4e86\u8868\u76ae\u7ec6\u80de\u4e2dEGFR\u7684\u8868\u8fbe\uff0c\u6210\u529f\u7684\u6539\u5584\u4e86\u53d7\u4f53\u8131\u654f\u95ee\u9898\u3002<\/p>\n<p>3\u3001\u8be5\u5de5\u4f5c\u8bc1\u660e\u4e86\u201c\u7535\u8f85\u52a9\u5242\u201d\u5728\u6539\u5584\u836f\u7269\u836f\u6548\u65b9\u9762\u5177\u6709\u5de8\u5927\u7684\u5e94\u7528\u524d\u666f\uff0c\u4e3a\u4f20\u7edf\u836f\u7269\u521b\u9020\u4e86\u5168\u65b0\u7684\u8054\u5408\u6cbb\u7597\u7b56\u7565\u3002<\/p>\n<p 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height=\"1631\" srcset=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/3-20.png 1271w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/3-20-234x300.png 234w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/3-20-768x986.png 768w, http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2022\/11\/3-20-798x1024.png 798w\" sizes=\"(max-width: 1271px) 100vw, 1271px\" \/><\/p>\n<p style=\"text-align: center;\">\u56fe3. mn-STESS\u4f53\u5916\u548c\u4f53\u5185\u7ed9\u836f<\/p>\n<p>(a)\u57fa\u4e8e\u4e0d\u540c\u8f7d\u836f\u6750\u6599\u7684MNP\u91ca\u653eEGF\u7684\u793a\u610f\u56fe\uff1a(i) cGel MNs\uff1b(ii) CMNP\u548cmn-STESS\u4e2d\u7684cGel-cHA MNs\uff1b(iii) CMNP (NS)\u548cmn-STESS (ES)\u7ec4\u4e2dEGF\u548cGSH\u5206\u5b50\u7684\u8fd0\u52a8\u3002(b)\u5177\u6709\u4e0d\u540c\u4ea4\u8054\u5ea6\u7684cGel 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