{"id":255459,"date":"2023-10-29T06:41:15","date_gmt":"2023-10-28T22:41:15","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=255459"},"modified":"2023-10-28T22:53:50","modified_gmt":"2023-10-28T14:53:50","slug":"%e6%96%bd%e5%89%91%e6%9e%97%e9%99%a2%e5%a3%ab-%e9%80%af%e5%90%91%e9%9b%a8-%e6%9d%8e%e6%96%8c-%e8%91%a3%e6%b5%b7%e9%9d%92%e5%8d%95%e5%8e%9f%e5%ad%90%e9%93%81%e5%82%ac%e5%8c%96%e5%89%82%e6%b2%bb","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=255459","title":{"rendered":"\u65bd\u5251\u6797\u9662\u58eb\uff1a\u57fa\u4e8e\u591a\u9176\u4eff\u751f\u5b66\u7684\u5355\u539f\u5b50\u94c1\u50ac\u5316\u5242\u6cbb\u7597\u94f6\u5c51\u75c5 Nat. Commun."},"content":{"rendered":"

\u8fd1\u65e5\uff0c\u540c\u6d4e\u5927\u5b66\u65bd\u5251\u6797\u9662\u58eb\/\u902f\u5411\u96e8\u52a9\u7406\u6559\u6388\u56e2\u961f\u8054\u5408\u540c\u6d4e\u5927\u5b66\u9644\u5c5e\u76ae\u80a4\u75c5\u533b\u9662\u674e\u658c\u6559\u6388\/\u84af\u4ec2\u56e2\u961f\u548c\u8463\u6d77\u9752\u56e2\u961f\u5728Nature Communications\u53d1\u8868\u9898\u4e3a\u201cSingle-atom catalysts-based catalytic ROS clearance for efficient psoriasis treatment and relapse prevention via restoring ESR1\u201d\u7684\u7814\u7a76\u8bba\u6587\u3002\u8be5\u7814\u7a76\u63d0\u51fa\u591a\u9176\u4eff\u751f\u5b66\uff08<\/strong>Multienzyme-inspired bionics, MIB<\/strong>\uff09\uff0c<\/strong>\u5373\u540c\u65f6\u6a21\u4eff\u591a\u79cd\u5929\u7136\u9176\u6d3b\u6027\u4e2d\u5fc3\u7ed3\u6784\u7684\u8bbe\u8ba1\u7406\u5ff5\uff0c\u5f00\u53d1\u51fa\u5177\u6709\u5e7f\u8c31ROS\u6e05\u9664\u80fd\u529b\u7684\u4eff\u751f\u5355\u539f\u5b50\u94c1\u50ac\u5316\u5242\uff08FeN4<\/sub>O2<\/sub>-SACs\uff09\uff0c\u901a\u8fc7\u4e0a\u8c03ESR1\u7684\u8868\u8fbe\uff0c\u6709\u6548\u5730\u6539\u5584\u4e86\u94f6\u5c51\u75c5\u7684\u708e\u75c7\u5e76\u9632\u6b62\u5176\u590d\u53d1\uff0c\u8bc1\u660e\u4e86\u94f6\u5c51\u75c5\u50ac\u5316\u7597\u6cd5\uff08<\/strong>Psoriasis catalytic therapy, PCT<\/strong>\uff09<\/strong>\u7684\u6cbb\u7597\u601d\u8def\u3002<\/p>\n

\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

\u56fe7. \u5c0f\u9f20\u76ae\u80a4\u635f\u4f24\u7684RNA\u6d4b\u5e8f\u548c\u5173\u952e\u86cb\u767dESR1\u7684\u9274\u5b9a<\/p>\n

\"\"<\/p>\n

\u56fe8. FeN4<\/sub>O2<\/sub>-SACs\u4e0a\u8c03ESR1\u6291\u5236\u94f6\u5c51\u75c5\u7684\u590d\u53d1\u3002<\/p>\n

\u603b\u4e4b\uff0c\u591a\u9176\u4eff\u751f\u50ac\u5316\u5242FeN4<\/sub>O2<\/sub>-SACs\u4e3a\u94f6\u5c51\u75c5\u63d0\u4f9b\u4e86\u4e00\u79cd”\u5b89\u5168\u3001\u6709\u6548\u3001\u957f\u671f<\/strong>“\u7684\u50ac\u5316\u6cbb\u7597\u6a21\u5f0f\uff0c\u662f\u591a\u9176\u4eff\u751f\u5b66\u7684\u4e00\u4e2a\u5178\u578b\u5e94\u7528\u3002<\/p>\n

Xiangyu Lu, Le Kuai, Fang Huang, Jingsi Jiang, Jiankun Song, Yiqiong Liu, Si Chen, Lijie Mao, Wei Peng, Ying Luo, Yongyong Li, Haiqing Dong*, Bin Li*, and Jianlin Shi*. Single-atom catalysts-based catalytic ROS clearance for efficient psoriasis treatment and relapse prevention via restoring ESR1<\/strong>. Nature Communications [J]. 2023, 14, 6767.<\/p>\n

\u6587\u7ae0\u94fe\u63a5\uff1ahttps:\/\/www.nature.com\/articles\/s41467-023-42477-y.pdf<\/p>\n

\u539f\u6587\u94fe\u63a5\uff1a https:\/\/doi.org\/10.1038\/s41467-023-42477-y<\/p>\n","protected":false},"excerpt":{"rendered":"

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