{"id":272139,"date":"2026-06-10T08:37:00","date_gmt":"2026-06-10T00:37:00","guid":{"rendered":"http:\/\/www.cailiaoniu.com\/?p=272139"},"modified":"2026-06-09T20:41:30","modified_gmt":"2026-06-09T12:41:30","slug":"%e7%87%95%e5%b1%b1%e5%a4%a7%e5%ad%a6%e9%ab%98%e5%a4%a7%e5%a8%81%e6%95%99%e6%8e%88biomaterials%ef%bc%9a%e5%8e%8b%e7%94%b5%e5%82%ac%e5%8c%96%e7%ba%b3%e7%b1%b3%e6%8d%a2%e8%83%bd%e5%99%a8%e9%80%9a","status":"publish","type":"post","link":"http:\/\/www.cailiaoniu.com\/?p=272139","title":{"rendered":"\u71d5\u5c71\u5927\u5b66\u9ad8\u5927\u5a01\u6559\u6388Biomaterials\uff1a\u538b\u7535\u50ac\u5316\u7eb3\u7c73\u6362\u80fd\u5668\u901a\u8fc7\u539f\u4f4d\u4ea7\u751f\u8fc7\u6c27\u4e9a\u785d\u9178\u76d0\u91cd\u5851\u80bf\u7624\u514d\u75ab\u4ee3\u8c22"},"content":{"rendered":"\n<p>01\u5bfc\u8bfb<\/p>\n\n\n\n<p>\u4e73\u817a\u764c\u4e2d\u81f4\u5bc6\u7684\u7ec6\u80de\u5916\u57fa\u8d28\uff08ECM\uff09\u548c\u57fa\u8d28\u7ec6\u80de\u6784\u6210\u4e86\u4e00\u4e2a\u5f3a\u5927\u7684\u7269\u7406\u548c\u514d\u75ab\u6291\u5236\u5c4f\u969c\uff0c\u6709\u52a9\u4e8e\u514d\u75ab\u9003\u907f\u548c\u80bf\u7624\u8fdb\u5c55\u3002\u5728\u8fd9\u79cd\u7ed3\u7f14\u7ec4\u7ec7\u589e\u751f\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff0c\u764c\u75c7\u76f8\u5173\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08CAFs\uff09\u8fc7\u5ea6\u8868\u8fbe\u5432\u54da\u80fa2,3-\u4e8c\u6c27\u5408\u9176-1\uff08IDO-1\uff09\uff0c\u8fd9\u79cd\u9176\u80fd\u6fc0\u6d3b\u8272\u6c28\u9178-\u72ac\u5c3f\u6c28\u9178\u4ee3\u8c22\u9014\u5f84\uff0c\u8bf1\u5bfcT\u7ec6\u80de\u8870\u7aed\u548c\u514d\u75ab\u8010\u53d7\u3002\u56e0\u6b64\uff0c\u8c03\u8282CAFs\u4e2d\u7684\u8272\u6c28\u9178\u4ee3\u8c22\u662f\u589e\u5f3a\u6297\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u4e00\u79cd\u6709\u524d\u9014\u7684\u7b56\u7565\u3002<\/p>\n\n\n\n<p>02\u6210\u679c\u63a0\u5f71<\/p>\n\n\n\n<p><strong>\u71d5\u5c71\u5927\u5b66\u9ad8\u5927\u5a01\u6559\u6388\u56e2\u961f<\/strong>\u5f00\u53d1\u4e86\u4e00\u79cd\u57fa\u4e8e\u8fbe\u6c99\u66ff\u5c3c\u8d1f\u8f7dNb<sub>2<\/sub>GeTe<sub>4<\/sub>\uff08NGT\uff09\u7eb3\u7c73\u7247\u7684CAF\u9776\u5411\u7eb3\u7c73\u836f\u7269\u7cfb\u7edf\uff0c\u7528\u4e8e\u8d85\u58f0\u4ecb\u5bfc\u7684\u514d\u75ab\u4ee3\u8c22\u8c03\u8282\u3002\u5728\u4f4e\u5f3a\u5ea6\u8d85\u58f0\u4e0b\uff0cNGT\u8868\u73b0\u51fa\u9ad8\u6548\u7684\u538b\u7535\u50ac\u5316\u7535\u8377\u5206\u79bb\uff0c\u6709\u6548\u5206\u79bb\u7535\u5b50-\u7a7a\u7a74\u5bf9\uff0c\u4ece\u800c\u5f15\u53d1\u8d85\u6c27\u9634\u79bb\u5b50\uff08\u22c5O<sub>2<\/sub><sup>&#8211;<\/sup>\uff09\u7684\u751f\u6210\u3002\u8fd9\u4e9b\u6d3b\u6027\u7269\u8d28\u4f1a\u8fc5\u901f\u4e0e\u7ec6\u80de\u5185\u7684\u4e00\u6c27\u5316\u6c2e\u53cd\u5e94\uff0c\u5f62\u6210\u8fc7\u6c27\u5316\u4e9a\u785d\u9178\u76d0\uff08ONOO\uff09\uff0c\u4ece\u800c\u8bf1\u5bfcIDO-1\u7684\u7279\u5b9a\u4f4d\u70b9\u916a\u6c28\u9178\u785d\u5316\u3002\u8fd9\u4e00\u8fc7\u7a0b\u4f1a\u4e0d\u53ef\u9006\u5730\u4f7fIDO-1\u5931\u6d3b\uff0c\u4ece\u800c\u7834\u574f\u8272\u6c28\u9178-\u72ac\u5c3f\u6c28\u9178\u514d\u75ab\u6291\u5236\u8f74\u3002\u540c\u65f6\uff0c\u8fbe\u6c99\u66ff\u5c3c\u7684\u63a7\u91ca\u6291\u5236\u4e86CAF\u4ecb\u5bfc\u7684\u7ea4\u7ef4\u5316\uff0c\u7834\u574f\u4e86\u57fa\u8d28\u5c4f\u969c\uff0c\u964d\u4f4e\u4e86\u80bf\u7624\u7684\u786c\u5ea6\uff0c\u4fc3\u8fdb\u4e86\u7ec6\u80de\u6bd2\u6027T\u6dcb\u5df4\u7ec6\u80de\u7684\u6d78\u6da6\u3002\u8fd9\u9879\u7814\u7a76\u5efa\u7acb\u4e86\u4e00\u79cd\u7cbe\u786e\u7684\u538b\u7535\u50ac\u5316\u9a71\u52a8\u7b56\u7565\uff0c\u7528\u4e8e\u91cd\u7f16\u7a0b\u7ea4\u7ef4\u5316\u6076\u6027\u80bf\u7624\u5fae\u73af\u5883\uff0c\u4e3a\u5f00\u53d1\u4e8c\u7ef4\u7eb3\u7c73\u6750\u6599\u7528\u4e8e\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u63d0\u4f9b\u4e86\u4e00\u6761\u524d\u666f\u5e7f\u9614\u7684\u9014\u5f84\u3002<\/p>\n\n\n\n<p>\u76f8\u5173\u8bba\u6587\u4ee5\u9898\u4e3a\u201cPiezocatalytic 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class=\"wp-image-272140\"\/><\/figure>\n\n\n\n<p><a><\/a>03\u521b\u65b0\u4e4b\u5904<\/p>\n\n\n\n<p><strong>\u539f\u4f4d\u751f\u6210ONOO\u207b<\/strong>\uff1a\u4f4e\u5f3a\u5ea6\u8d85\u58f0\u4e0b\u538b\u7535\u50ac\u5316\u751f\u6210\u8fc7\u6c27\u4e9a\u785d\u9178\u76d0\uff0c\u7a81\u7834ROS\u534a\u8870\u671f\u74f6\u9888\u3002<\/p>\n\n\n\n<p><strong>IDO-1\u4e0d\u53ef\u9006\u785d\u5316<\/strong>\uff1a\u901a\u8fc7\u916a\u6c28\u9178\u4f4d\u70b9\u7279\u5f02\u6027\u785d\u5316\u4f7fIDO-1\u6c38\u4e45\u5931\u6d3b\uff0c\u963b\u65ad\u514d\u75ab\u6291\u5236\u4ee3\u8c22\u3002<\/p>\n\n\n\n<p><strong>\u4e34\u5e8a\u8d85\u58f0\u91cd\u7f16\u7a0b<\/strong>\uff1a\u5728\u5b89\u5168\u8d85\u58f0\u53c2\u6570\u4e0b\u540c\u6b65\u5b9e\u73b0\u4ee3\u8c22\u9006\u8f6c\u4e0e\u57fa\u8d28\u6b63\u5e38\u5316\uff0c\u6291\u5236\u7387\u8fbe86%\u3002<\/p>\n\n\n\n<p>04\u6570\u636e\u6982\u89c8<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"530\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/ce6e2814f207c93-3.png\" alt=\"\" class=\"wp-image-272141\"\/><\/figure>\n\n\n\n<p><strong>\u56fe1\u3001<\/strong><strong>\u4eff\u751f NGT\/DAS@C \u5236\u9020\u793a\u610f\u56fe\u3001\u538b\u7535\u9a71\u52a8 IDO-1 \u785d\u5316\u539f\u7406\u4ee5\u53ca\u514d\u75ab\u4ee3\u8c22\u91cd\u7f16\u7a0b\u548c\u57fa\u8d28\u6b63\u5e38\u5316\u7684\u534f\u540c\u673a\u5236<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"539\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/7f88dbbcaa77a1d-3.png\" alt=\"\" class=\"wp-image-272142\"\/><\/figure>\n\n\n\n<p><strong>\u56fe2\u3001<\/strong><strong>NGT\/DAS@C\u7684\u5236\u5907\u548c\u8868\u5f81<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"491\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/4e9a0ba2491dfde-2.png\" alt=\"\" class=\"wp-image-272143\"\/><\/figure>\n\n\n\n<p><strong>\u56fe3\u3001<\/strong><strong>Nb<\/strong><strong><sub><strong><sub>2<\/sub><\/strong><\/sub><\/strong><strong>GeTe<\/strong><strong><sub><strong><sub>4<\/sub><\/strong><\/sub><\/strong><strong>\u7684\u538b\u7535\u548c\u7535\u5b50\u7279\u6027<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"597\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/b14210e1ee30421-2.png\" alt=\"\" class=\"wp-image-272144\"\/><\/figure>\n\n\n\n<p><strong>\u56fe4\u3001<\/strong><strong>\u4f53\u5916\u7eb3\u7c73\u836f\u7269\u8c03\u8282CAF\u7684\u6b63\u5e38\u5316<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"564\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/de5bcf7d8eaea98-2.png\" alt=\"\" class=\"wp-image-272145\"\/><\/figure>\n\n\n\n<p>\u56fe5\u3001\u4f53\u5916\u8bd5\u9a8c\u6291\u5236IDO-1\u7684\u8868\u8fbe\uff0c\u589e\u5f3aT\u7ec6\u80de\u7684\u6bd2\u6027<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"567\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/aa3023e0288002c-2.png\" alt=\"\" class=\"wp-image-272146\"\/><\/figure>\n\n\n\n<p><strong>\u56fe6\u3001<\/strong><strong>\u6291\u5236IDO-1\u4ecb\u5bfc\u7684\u8272\u6c28\u9178\u4ee3\u8c22\uff0c\u964d\u4f4e\u4f53\u5185\u80bf\u7624\u57fa\u8d28\u7684\u786c\u5ea6<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"550\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/e2f457ec632c1f6-1.png\" alt=\"\" class=\"wp-image-272147\"\/><\/figure>\n\n\n\n<p><strong>\u56fe7\u3001\u4f53\u5185<\/strong><strong>\u514d\u75ab\u6548\u5e94<\/strong><strong>\u6fc0\u6d3b<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"550\" height=\"562\" src=\"http:\/\/www.cailiaoniu.com\/wp-content\/uploads\/2026\/06\/bf2e94a56e16c6a-1.png\" alt=\"\" class=\"wp-image-272148\"\/><\/figure>\n\n\n\n<p><strong>\u56fe8\u3001<\/strong><strong>\u4f53\u5185\u6297\u80bf\u7624\u7597\u6548\u548c\u751f\u7269\u5b89\u5168\u6027\u8bc4\u4f30<\/strong><strong><\/strong><\/p>\n\n\n\n<p>05\u7ed3\u8bba<\/p>\n\n\n\n<p>\u6211\u4eec\u5f00\u53d1\u7684\u57fa\u4e8eNb<sub>2<\/sub>GeTe<sub>4<\/sub>\u7eb3\u7c73\u7247\u7684\u4f4e\u5f3a\u5ea6\u8d85\u58f0\uff08LIUS\uff09\u54cd\u5e94\u538b\u7535\u7eb3\u7c73\u6362\u80fd\u5668\uff0c\u80fd\u5728\u80bf\u7624\u57fa\u8d28\u5185\u8fdb\u884c\u50ac\u5316\u4ee3\u8c22\u5e72\u9884\u3002\u5728\u4f4e\u5f3a\u5ea6\u8d85\u58f0\u6fc0\u6d3b\u65f6\uff0cNb<sub>2<\/sub>GeTe<sub>4<\/sub>\u4f1a\u4ea7\u751f\u5f3a\u5927\u7684\u538b\u7535\u52bf\uff0c\u63a8\u52a8\u6d3b\u6027ONOO<sup>&#8211;<\/sup>\u7269\u79cd\u7684\u5f62\u6210\uff0c\u5bfc\u81f4\u7279\u5b9a\u4f4d\u70b9\u7684\u785d\u5316\u548c\u6291\u5236\u764c\u75c7\u76f8\u5173\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08CAFs\uff09\u4e2d\u7684IDO-1\u3002\u8fd9\u4e00\u8fc7\u7a0b\u6709\u6548\u5730\u91cd\u65b0\u5f15\u5bfc\u4e86\u8272\u6c28\u9178\u4ee3\u8c22\uff0c\u51cf\u8f7b\u4e86CAF\u4ecb\u5bfc\u7684\u514d\u75ab\u6291\u5236\uff0c\u5e76\u6062\u590d\u4e86\u4f53\u5185\u7684\u6297\u80bf\u7624\u514d\u75ab\u6fc0\u6d3b\u3002\u7535\u5b50\u7ed3\u6784\u5206\u6790\u8868\u660e\uff0cNb<sub>2<\/sub>GeTe<sub>4<\/sub>\u7684\u8d85\u7a84\u5e26\u9699\u548c\u9ad8\u8f7d\u6d41\u5b50\u8fc1\u79fb\u7387\u6709\u52a9\u4e8e\u5728\u8f7b\u5fae\u673a\u68b0\u523a\u6fc0\u4e0b\u9ad8\u6548\u6fc0\u53d1\u548c\u5206\u79bb\u7535\u8377\uff0c\u4ece\u800c\u5728\u4e34\u5e8a\u76f8\u5173\u7684LIUS\u6761\u4ef6\u4e0b\u5b9e\u73b0\u5f3a\u5927\u7684\u538b\u7535\u50ac\u5316\u6d3b\u6027\u3002\u9664\u4e86\u8bc1\u660e Nb<sub>2<\/sub>GeTe<sub>4<\/sub>\u662f\u4e00\u79cd\u5f88\u6709\u524d\u666f\u7684\u7528\u4e8e\u514d\u75ab\u8c03\u8282\u7684\u538b\u7535\u7eb3\u7c73\u50ac\u5316\u5242\u4e4b\u5916\uff0c\u8fd9\u9879\u5de5\u4f5c\u8fd8\u5efa\u7acb\u4e86\u4e00\u4e2a\u6982\u5ff5\u6846\u67b6\uff0c\u5176\u4e2d\u673a\u68b0\u6fc0\u6d3b\u7684\u7eb3\u7c73\u6362\u80fd\u5668\u53ef\u9009\u62e9\u6027\u5730\u91cd\u65b0\u89c4\u5212\u57fa\u8d28\u4ee3\u8c22\uff0c\u800c\u4e0d\u662f\u7834\u574f\u6027\u5730\u6d88\u9664\u57fa\u8d28\u6210\u5206\u3002\u8fd9\u79cd\u7b56\u7565\u51f8\u663e\u4e86\u538b\u7535\u50ac\u5316\u4f5c\u4e3a\u80bf\u7624\u5fae\u73af\u5883\u91cd\u5851\u7684\u53ef\u63a7\u65b9\u6cd5\u7684\u6f5c\u529b\uff0c\u5e76\u53ef\u80fd\u6fc0\u53d1\u673a\u68b0\u9a71\u52a8\u7684\u7eb3\u7c73\u50ac\u5316\u5728\u514d\u75ab\u7597\u6cd5\u548c\u76f8\u5173\u751f\u7269\u533b\u5b66\u9886\u57df\u7684\u66f4\u5e7f\u6cdb\u5e94\u7528\u3002<\/p>\n\n\n\n<p>06\u8bba\u6587\u4fe1\u606f<\/p>\n\n\n\n<p>Zhang Jinhui, Yan Junxin, Ye Kun, Fu Yang, Dong Zhechen, Zhang Xuwu, He Yuchu, Liu Yingdan, Yan Xiyun, Xue Weili, Tu Wenkang, Gao Dawei. Piezocatalytic nanotransducers rewire tumor immunometabolism via in situ peroxynitrite generation. Biomaterials, 2026, 335: 124353. DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.biomaterials.2026.124353\"><u>10.1016\/j.biomaterials.2026.124353<\/u><\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/authors.elsevier.com\/a\/1nDU9WWN15xL1\">https:\/\/authors.elsevier.com\/a\/1nDU9WWN15xL1<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>01\u5bfc\u8bfb \u4e73\u817a\u764c\u4e2d\u81f4\u5bc6\u7684\u7ec6\u80de\u5916\u57fa\u8d28\uff08ECM\uff09\u548c\u57fa\u8d28\u7ec6\u80de\u6784\u6210\u4e86\u4e00\u4e2a\u5f3a\u5927\u7684\u7269\u7406\u548c\u514d\u75ab\u6291\u5236\u5c4f\u969c\uff0c\u6709\u52a9\u4e8e\u514d\u75ab\u9003\u907f\u548c\u80bf\u7624\u8fdb\u5c55\u3002\u5728\u8fd9\u79cd\u7ed3\u7f14\u7ec4\u7ec7\u589e\u751f\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff0c\u764c\u75c7\u76f8\u5173\u6210\u7ea4&#8230;<\/p>\n","protected":false},"author":31345,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-272139","post","type-post","status-publish","format-standard","hentry","category-keji"],"_links":{"self":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/272139"}],"collection":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/users\/31345"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=272139"}],"version-history":[{"count":1,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/272139\/revisions"}],"predecessor-version":[{"id":272149,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=\/wp\/v2\/posts\/272139\/revisions\/272149"}],"wp:attachment":[{"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=272139"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=272139"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.cailiaoniu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=272139"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}